English Journal
- Galactose-based Thermosensitive Nanogels for Targeted Drug Delivery of Iodoazomycin Arabinofuranoside (IAZA) for Theranostic Management of Hypoxic Hepatocellular Carcinoma.
- Quan S1, Wang Y1, Zhou A, Kumar P, Narain R1.
- Biomacromolecules.Biomacromolecules.2015 Jul 13;16(7):1978-86. doi: 10.1021/acs.biomac.5b00576. Epub 2015 Jun 3.
- In this study, galactose-based nanogels were prepared by reversible addition-fragmentation chain transfer process to facilitate the targeted delivery of iodoazomycin arabinofuranoside (IAZA), a clinical drug for imaging solid hypoxic tumors, and evaluate its role in hypoxia-selective (radio)theranos
- PMID 25996799
- A phase Ib/II translational study of sunitinib with neoadjuvant radiotherapy in soft-tissue sarcoma.
- Lewin J1, Khamly KK1, Young RJ1, Mitchell C1, Hicks RJ2, Toner GC2, Ngan SY1, Chander S1, Powell GJ3, Herschtal A1, Te Marvelde L1, Desai J1, Choong PF3, Stacker SA4, Achen MG4, Ferris N1, Fox S1, Slavin J5, Thomas DM6.
- British journal of cancer.Br J Cancer.2014 Dec 9;111(12):2254-61. doi: 10.1038/bjc.2014.537. Epub 2014 Oct 16.
- BACKGROUND: Preoperative radiotherapy (RT) is commonly used to treat localised soft-tissue sarcomas (STS). Hypoxia is an important determinant of radioresistance. Whether antiangiogenic therapy can 'normalise' tumour vasculature, thereby improving oxygenation, remains unknown.METHODS: Two cohorts we
- PMID 25321190
Japanese Journal
- Iodine-124-labeled iodo-azomycin-galactoside imaging of tumor hypoxia in mice with serial microPET scanning
- Synthesis of 1-β-D-(5-Deoxy-5-iodoarabinofuranosyl)-2-nitroimidazole (β-IAZA) : A Novel Marker of Tissue Hypoxia
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