autotransplant

• 自家移植する

関

autograft、autologous transplantation、autotransplantation

WordNet

1. tissue that is taken from one site and grafted to another site on the same person; "skin from his thigh replaced the burned skin on his arms" (同)autoplasty

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/10/02 20:48:02」(JST)

wiki en

[Wiki en表示]

Autotransplantation
Intervention
MeSH	D014182

Autotransplantation is the transplantation of organs, tissues or even proteins from one part of the body to another in the same individual. Tissue transplanted by such "autologous" procedure is referred to as an autograft or autotransplant. It is contrasted with xenotransplantation (from other species) and allotransplantation (from other individual of same species). A common example is when a piece of bone (usually from the hip) is removed and ground into a paste when reconstructing another portion of bone.

Autologous blood donation

See also: Intraoperative blood salvage

In blood banking terminology, autologous blood donation refers to a blood donation marked for use by the donor, typically for a scheduled surgery. (Generally, the notion of "donation" does not refer to giving to one's self, though in this context it has become somewhat acceptably idiomatic.) They are commonly called "Autos" by blood bank personnel, and it is one major form of the more general concept of autotransfusion (the other being intraoperative blood salvage).

Some advantages of autologous blood donation are:

• Blood type will always match, even with a rare blood type or antibody type.
• If only autologous blood is used during surgery the risk of exposure to infectious disease such as hepatitis or HIV from blood is eliminated.
• The risk of allergic reactions is reduced.

The disadvantages are:

• Higher cost due to individualized processing, record-keeping, and management.
• In most cases, the blood is discarded if it is not used instead of being added to the general supply.
• Blood donation prior to colorectal cancer surgery seemed causative for a worse overall and colorectal cancer specific survival.

Autologous blood is not routinely tested for infectious diseases markers such as HIV antibodies. In the United States, autologous blood is tested only if it is collected in one place and shipped to another.

There is also a risk that, in an emergency or if more blood is required than has been set aside in advance, the patient could still be exposed to donor blood instead of autologous blood. Autologous donation is also not suitable for patients who are medically unable to or advised not to give blood, such as cardiac patients or small children and infants.

Bone autograft

See also: Bone grafting#Autologous bone grafting

In orthopaedic medicine, bone graft can be sourced from a patient's own bone in order to fill space and produce an osteogenic response in a bone defect. However, due to the donor-site morbidity associated with autograft, other methods such as bone allograft and bone morphogenetic proteins and synthetic graft materials are often used as alternatives. Autografts have long been considered the "Gold Standard" in Oral Surgery and Implant Dentistry because it offered the best regenerations results. Lately, the introduction of morphogen-enhanced bone graft substitutes have shown to show similar success rates and quality of regeneration; however, their price is still very high.

Autologous organ graft

Recent advances in decellularization have allowed researchers to recreate an organ using a patient's own tissue cells that are grafted on an allograft protein scaffold.

See also

• Autotransfusion - the process of returning to a patient their own blood that has been lost.
• Replantation - reattaching a severed limb or other part of the body.
• Rotationplasty - attaching the foot with ankle joint (reversed) to the femur to replace the knee.

External links

• AABB
• America's Blood Centers
• American Red Cross
• NIH
• PBS - Red Gold
• Are autologous donations cost-effective?
• BloodBook
• Autotransplantation infos

References

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

• 1. 医原性尿菅損傷の外科的修復 surgical repair of an iatrogenic ureteral injury
• 2. 慢性膵炎の治療 treatment of chronic pancreatitis
• 3. 初回および再手術の甲状腺摘除術 initial and reoperative thyroidectomy
• 4. 生殖腺毒性を有する治療または生殖腺切除術を施行した患者における不妊の予防 fertility preservation in patients undergoing gonadotoxic treatment or gonadal resection

English Journal

• Study of proliferation and 3D epidermal reconstruction from foreskin, auricular and trunk keratinocytes in children.

• Mcheik JN1, Barrault C2, Pedretti N2, Garnier J2, Juchaux F2, Levard G3, Morel F4, Bernard FX5, Lecron JC6.
• Burns : journal of the International Society for Burn Injuries.Burns.2015 Mar;41(2):352-8. doi: 10.1016/j.burns.2014.07.003. Epub 2014 Sep 16.
• OBJECTIVE: Severe burns in children are conventionally treated with split-thickness skin autografts or epidermal sheets. An alternative approach is to graft isolated keratinocytes. We evaluated foreskin and other anatomic sites as donor sources for autologous keratinocyte graft in children. We studi
• PMID 25234956

• A Crucial Role of IL-17 in Bone Resorption During Rejection of Fresh Bone Xenotransplantation in Rats.

• Sun J1, Wang X, Fu C, Wang D, Bi Z.
• Cell biochemistry and biophysics.Cell Biochem Biophys.2015 Mar;71(2):1043-9. doi: 10.1007/s12013-014-0307-8.
• Bone grafting is a very useful approach to reconstruction of skeletal defects. However, the clinical use of autografts, allografts, and synthetic products is associated with a number of problems. The use of bone xenotransplantation, on the other hand, is associated with strong immune response, and t
• PMID 25331672

• Current wound healing procedures and potential care.

• Dreifke MB1, Jayasuriya AA2, Jayasuriya AC3.
• Materials science & engineering. C, Materials for biological applications.Mater Sci Eng C Mater Biol Appl.2015 Mar 1;48C:651-662. doi: 10.1016/j.msec.2014.12.068. Epub 2014 Dec 19.
• In this review, we describe current and future potential wound healing treatments for acute and chronic wounds. The current wound healing approaches are based on autografts, allografts, and cultured epithelial autografts, and wound dressings based on biocompatible and biodegradable polymers. The Foo
• PMID 25579968

Japanese Journal

• 症例報告 歯根未完成歯の自家歯牙移植--歯の銀行の役割

• 河田 俊嗣,加来 真人,小跡 弘幸 [他]
• 広島大学歯学雑誌 42(2), 180-184, 2010-12
• NAID 40018838830

• Non-cryopreserved unmanipulated hematopoietic peripheral blood stem cell autotransplant program: long-term results

• RUIZ-ARGUELLES GJ.
• Arch Med Res. 30, 380-384, 1999
• NAID 30008736315

• Intra-operative radiation therapy in autotransplant for neuroblastoma

• MUGISHIMA H,IWATA M,OKABE I,TANAKA Y,HARADA K
• Acta paediatrica Japonica 37(1), 122-124, 1995-02-01
• NAID 10010502436

Related Links

• Autotransplantation - Wikipedia, the free encyclopedia

Tissue transplanted by such "autologous" procedure is referred to as an autograft or autotransplant. It is contrasted with xenotransplantation (from other species) and allotransplantation (from other individual of same species). A common ...

• Autotransplant - Medical Definition and More from Merriam-Webster

Definition of autotransplant from Merriam-Webster's Medical Dictionary with examples and pronunciations.

Related Pictures

---

★リンクテーブル★

リンク元	「autologous transplantation」
拡張検索	「autotransplantation」

「autologous transplantation」

　　[★]

• 自家移植

関

autograft、autotransplant、autotransplantation

「autotransplantation」

　　[★]

• 自家移植、個体内移植

関

autograft、autologous transplantation、autotransplant