Japanese Journal

Synthesis of N^3-Substituted Uridine and Related Pyrimidine Nucleosides and Their Antinociceptive Effects in Mice

, , [他], , ,
Chemical & pharmaceutical bulletin 53(3), 313-318, 2005-03-01
… Seventy eight N^3-substituted derivatives of uridine (1), thymidine (2), 2'-deoxyuridine (3), 6-azauridine (4), 2', 3'-O-isopropylideneuridine (5), and arabinofuranosyluracil (6) were synthesized and their antinociceptive effects were evaluated. … N^3-(2', 4'-Dimethoxyphenacyl)uridine (1l), N^3-(2', 4'-dimethoxyphenacyl)2'-deoxyuridine (3l), and N^3-(2', 5'-dimethoxyphenacyl)arabinofuranosyluracil (6m) possessed 93, 86, and 82% of the antinociceptive effects tested by hot plate, respectively. …
NAID 10016652649

5位置換ピリミジンヌクレオシドを含むオリゴヌクレオチドの合成とその性質

尾崎広明,〓原正靖,澤井宏明
有機合成化学協会誌 : JOURNAL OF Synthetic Organic Chemistry JAPAN 62(12), 1238-1248, 2004-12-01
… 5-Substituted 2 '-deoxyuridine derivatives and 5-substituted arabinofuranosyluracil derivatives were synthesized from 2, 2 '-anhydro-5-methoxycarbonylmethyluridine, which was synthesized from arabinoaminooxazoline and dimethyl α-bromomethylfumarate. …
NAID 10014119789

Pharmacokinetics of the thymidine analog 2'-fluoro-5-methyl-1-beta-D-arabinofuranosyluracil (FMAU) in tumor-bearing rats

BADING JR
Nucl Med Biol 31, 407-418, 2004
NAID 30003369521

Related Pictures

bromvinyl 1β d arabinofuranosyluracil 5 e Arabinofuranosyluracil -13C www β-D- arabinofuranosyluracil Figure US20060009401A1-20060112-C00001 β-l- arabinofuranosyluracil Bystander effect of purine nucleoside