ピリミジン塩基のない、脱ピリミジン塩基の
English Journal
- Structure-based virtual screening toward the discovery of novel inhibitors of the DNA repair activity of the human apurinic/apyrimidinic endonuclease 1.
- Guerreiro PS1, Estácio SG2, Antunes F3, Fernandes AS1,4, Pinheiro PF1,5, Costa JG1,4, Castro M1, Miranda JP1, Guedes RC6, Oliveira NG7.
- Chemical biology & drug design.Chem Biol Drug Des.2016 Dec;88(6):915-925. doi: 10.1111/cbdd.12826. Epub 2016 Sep 16.
- The DNA repair activity of human apurinic/apyrimidinic endonuclease 1 (APE1) has been recognized as a promising target for the development of small-molecule inhibitors to be used in combination with anticancer agents. In an attempt to identify novel inhibitors of APE1, we present a structure-based v
- PMID 27450574
- The major Arabidopsis thaliana apurinic/apyrimidinic endonuclease, ARP is involved in the plant nucleotide incision repair pathway.
- Akishev Z1, Taipakova S1, Joldybayeva B1, Zutterling C2, Smekenov I1, Ishchenko AA2, Zharkov DO3, Bissenbaev AK4, Saparbaev M5.
- DNA repair.DNA Repair (Amst).2016 Dec;48:30-42. doi: 10.1016/j.dnarep.2016.10.009. Epub 2016 Oct 29.
- Apurinic/apyrimidinic (AP) endonucleases are important DNA repair enzymes involved in two overlapping pathways: DNA glycosylase-initiated base excision (BER) and AP endonuclease-initiated nucleotide incision repair (NIR). In the BER pathway, AP endonucleases cleave DNA at AP sites and 3'-blocking mo
- PMID 27836324
- Systematic identification of synthetic lethal mutations with reduced-genome Escherichia coli: synthetic genetic interactions among yoaA, xthA and holC related to survival from MMS exposure.
- Watanabe K1, Tominaga K, Kitamura M, Kato JI.
- Genes & genetic systems.Genes Genet Syst.2016 Nov 26;91(3):183-188. Epub 2016 May 2.
- Reduced-genome Escherichia coli strains lacking up to 38.9% of the parental chromosome have been constructed by combining large-scale chromosome deletion mutations. Functionally redundant genes involved in essential processes can be systematically identified using these reduced-genome strains. One l
- PMID 27150717
Japanese Journal
- Formation of the Nitrative DNA Lesion 8-Nitroguanine is Associated with Asbestos Contents in Human Lung Tissues: A Pilot Study
- Hiraku Yusuke,Sakai Kiyoshi,Shibata Eiji,Kamijima Michihiro,Hisanaga Naomi,Ma Ning,Kawanishi Shosuke,Murata Mariko
- Journal of Occupational Health 56(3), 186-196, 2014
- … Results: In subjects without mesothelioma, staining intensities of 8-nitroG and apurinic/apyrimidinic endonuclease 1 (APE1) were significantly correlated with total asbestos and amphibole contents (p<0.05), but not with chrysotile content. …
- NAID 130004447649
- Apurinic/apyrimidinic endonuclease-1 (APE-1) is overexpressed via the activation of NF-κB-p65 in MCP-1-positive esophageal squamous cell carcinoma tissue
- Song Junmin,Futagami Seiji,Nagoya Hiroyuki,Kawagoe Tetsuro,Yamawaki Hiroshi,Kodaka Yasuhiro,Tatsuguchi Atsushi,Gudis Katya,Wakabayashi Taiga,Yonezawa Masaoki,Shimpuku Mayumi,Watarai Yasuhiko,Iwakiri Katsuhiko,Hoshihara Yoshio,Makino Hiroshi,Miyashita Masao,Tsuchiya Shinichi,Li Yan,E. Crowe Sheila,Sakamoto Choitsu
- Journal of Clinical Biochemistry and Nutrition 52(2), 112-119, 2013
- … Apurinic/apyrimidinic endonuclease-1 (APE-1), a key enzyme responsible for DNA base excision repair (BER), has been linked to cancer chemoradiosensitivity. …
- NAID 130004466710
- Effects of High-Pressure Carbonation on Intracellular ATP and NADH Levels and DNA Damage in <I>Escherichia coli</I> Cells
- KLANGPETCH WANNAPORN,NOMA SEIJI,IGURA NORIYUKI,SHIMODA MITSUYA
- Biocontrol Science 18(4), 199-203, 2013
- … coli</I>, intracellular ATP, and intracellular NADH, and increased the number of apurinic/apyrimidinic sites. …
- NAID 130003385900
Related Links
- Definition of Apyrimidinic with photos and pictures, translations, sample usage, and additional links for more information. ... ¹ Source: wiktionary.com Apyrimidinic Pictures Click the following link to bring up a new window with an ...
- Acronym Finder: AP stands for Apyrimidinic. This definition appears very rarely ... Subsequent digestion with uracil N-glycosylase, which releases uracil from both single-stranded and double-stranded DNA and thus creates apyrimidinic ...
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★リンクテーブル★
| リンク元 | 「脱ピリミジン塩基」「ピリミジン塩基のない」 |
| 拡張検索 | 「apurinic-apyrimidinic DNA lyase」「apurinic-apyrimidinic endonuclease」「apyrimidinic endonuclease」 |
「脱ピリミジン塩基」
「ピリミジン塩基のない」
- 英
- apyrimidinic
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- 脱ピリミジン塩基