抗緑膿菌ペニシリン
WordNet
- any of various antibiotics obtained from Penicillium molds (or produced synthetically) and used in the treatment of various infections and diseases
PrepTutorEJDIC
- ペニシリン(坑生物質の一種)
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/07/30 09:36:44」(JST)
[Wiki en表示]
The extended-spectrum penicillins are a group of antibiotics that have the widest antibacterial spectrum of all penicillins.[1] Some sources identify them with antipseudomonal penicillins,[2] others consider these types to be distinct.[3] This group includes the carboxypenicillins and the ureidopenicillins. Aminopenicillins, in contrast, do not have activity against Pseudomonas species, as their positively charged amino group does not hinder degradation by bacterially produced beta-lactamases.[4]
Products
- Ureidopenicillins
- Azlocillin
- Mezlocillin
- Piperacillin
- Carboxypenicillins
- Ticarcillin (generally in the combination ticarcillin/clavulanic acid)
- Carbenicillin
- Mecillinam
See also
- Pseudomonas aeruginosa#Treatment
References
- ^ Comprehensive Pharmacy Review, Leon Shargel, 6th edition, p917
- ^ Elsevier's Integrated Review Pharmacology, By Mark Kester, Kelly Dowhower Karpa, Kent E. Vrana, subclassification of penicillins section
- ^ edited by Michelle A. Clark, Richard A. Harvey, Richard Finkel, Jose A. Rey, Karen Whalen, p383
- ^ Golan, David E. Principles of Pharmacology (2 ed.). Lippincott Williams & Wilkins. p. 610. ISBN 1608312704.
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Antibacterials: cell envelope antibiotics (J01C-J01D)
|
|
| Intracellular |
- Inhibit peptidoglycan subunit synthesis and transport: NAM synthesis inhibition (Fosfomycin)
- DADAL/AR inhibitors (Cycloserine)
- bactoprenol inhibitors (Bacitracin)
|
|
| Glycopeptide |
- Inhibit PG chain elongation: Vancomycin# (Oritavancin
- Telavancin)
- Teicoplanin (Dalbavancin)
- Ramoplanin
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β-lactams/
(inhibit PBP
cross-links) |
|
|
| Other |
- polymyxins/detergent
- depolarizing
- Hydrolyze NAM-NAG
- Gramicidin
- Isoniazid
- Teixobactin
|
|
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
|
UpToDate Contents
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English Journal
- Ability to develop Pseudomonas aeruginosa clinical infections according to the prior rectal colonization status: a prospective observational study.
- Gómez-Zorrilla S1, Camoez M2, Tubau F2, Cañizares R3, Periche E3, Dominguez MA2, Ariza J1, Peña C4.
- Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2015 Jun 15. pii: AAC.04636-14. [Epub ahead of print]
- The potential role of Pseudomonas aeruginosa (PA) intestinal colonization in subsequent development of infections has not been deeply investigated. The aims of this study were to assess the role of PA intestinal colonization as predictor of subsequent infection and to investigate risk factors associ
- PMID 26077248
- Stenotrophomonas maltophilia: Complicating treatment of ESBL UTI.
- Kumar S1, Bandyopadhyay M1, Chatterjee M1, Banerjee P1, Poddar S1, Banerjee D1.
- Advanced biomedical research.Adv Biomed Res.2015 Feb 11;4:36. doi: 10.4103/2277-9175.151241. eCollection 2015.
- Stenotrophomonas maltophilia (S. maltophilia) is a gram-negative bacillus emerging as an opportunistic, nosocomial pathogen associated with a high mortality rate. The organism has been shown to survive several biocides used in the hospital setting. Hospital water sources can serve as a reservoir for
- PMID 25789262
- Antibiotic self-stewardship: trainee-led structured antibiotic time-outs to improve antimicrobial use.
- Lee TC, Frenette C, Jayaraman D, Green L, Pilote L.
- Annals of internal medicine.Ann Intern Med.2014 Nov 18;161(10 Suppl):S53-8. doi: 10.7326/M13-3016.
- BACKGROUND: Antibiotic use is an important quality improvement target. Nearly 50% of antibiotic use is unnecessary or inappropriate. To combat overuse, the Centers for Disease Control and Prevention (CDC) proposed "time-outs" to reevaluate antibiotics.OBJECTIVE: To optimize antibiotic use through tr
- PMID 25402404
Japanese Journal
- 感染防止対策加算連携施設間における抗菌薬使用量サーベイランスの評価
- 血液培養から分離されたメチシリン耐性ブドウ球菌について 菌の疫学的特徴とβ‐ラクタム系薬によるペニシリン結合蛋白‐２′の誘導:菌の疫学的特徴とβ-ラクタム系薬によるペニシリン結合蛋白-2'の誘導
- Azthreonam (SQ26, 776) の抗菌力, β-lactamase安定性および補体と白血球との協力的殺菌作用
Related Links
- Antipseudomonal penicillins are antimicrobial agents, which are used to treat pseudomonal infections. They have the activity of penicillins and aminopenicillins, and additional activity against Pseudomonas, Enterococcus ...
- Pseudomonas infection can be treated with a combination of an antipseudomonal beta-lactam (eg, penicillin or cephalosporin) and an aminoglycoside. Carbapenems (eg, imipenem, meropenem) with antipseudomonal quinolones ...
★リンクテーブル★
[★]
- 英
- antipseudomonal penicillins
- 関
- 緑膿菌、ペニシリン系抗菌薬