- n.
- (プロテアーゼ阻害薬の総称) アンチプロテアーゼ
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- 1. 安定した慢性閉塞性肺疾患（COPD）のマネージメント management of stable chronic obstructive pulmonary disease
- 2. 嚢胞性線維症：遺伝学と病因 cystic fibrosis genetics and pathogenesis
- 3. 急性膵炎の発症機序 pathogenesis of acute pancreatitis
- 4. 嚢胞性線維症：肺疾患の臨床症状 cystic fibrosis clinical manifestations of pulmonary disease
English Journal
- Design, virtual screening and docking study of novel NS3 inhibitors by targeting protein-protein interacting sites of dengue virus - a novel approach.
- Parida P, Yadav RN, Sarma K, Nainwal LM1.
- Current pharmaceutical biotechnology.Curr Pharm Biotechnol.2014 Nov;14(11):995-1008.
- Currently dengue is a serious disease which has become a global burden in the last decade. Unfortunately, there are no effective drugs and vaccines against this disease. DENV non-structural protein (NS) 3, which is viral protease which is a potential target for antiviral therapy. Targeting this we p
- PMID 24372240
- Autophagy inhibitors promoted aristolochic acid I induced renal tubular epithelial cell apoptosis via mitochondrial pathway but alleviated nonapoptotic cell death in mouse acute aritolochic acid nephropathy model.
- Zeng Y1, Li S, Wu J, Chen W, Sun H, Peng W, Yu X, Yang X.
- Apoptosis : an international journal on programmed cell death.Apoptosis.2014 Aug;19(8):1215-24. doi: 10.1007/s10495-014-0996-x.
- Aristolochic acid I (AAI) can induce renal tubular epithelial cells (RTECs) autophagy, which thereby extenuates apoptosis in vitro. In this study, we aimed to determine whether the in vitro data also apply to the AAI-induced pathologic condition in vivo. BALB/c mice were treated with AAI, autophagy
- PMID 24841932
- Substrate profiling of Finegoldia magna SufA protease, inhibitor screening and application to prevent human fibrinogen degradation and bacteria growth in vitro.
- Burchacka E1, Sieńczyk M2, Frick IM3, Wysocka M4, Lesner A4, Oleksyszyn J2.
- Biochimie.Biochimie.2014 Aug;103:137-43. doi: 10.1016/j.biochi.2014.05.006. Epub 2014 May 22.
- SufA, which belongs to the subtilisin-like serine protease family, contains a non-canonical Asp-His-Ser catalytic triad. Under in vitro conditions, SufA is capable of human fibrinogen hydrolysis leading to inhibition of fibrin network formation, thus suggesting its important role in the development
- PMID 24859537
Japanese Journal
- Attenuated induction of epithelial and leukocyte serine antiproteases elafin and secretory leukocyte protease inhibitor in Crohn's disease
- SCHMID M
- J Leukoc Biol 81, 907-915, 2007
- NAID 30024213711
- The Kallikrein-Kinin System : Current and Future Pharmacological Targets
- Moreau Marie Eve,Garbacki Nancy,Molinaro Giuseppe [他],BROWN Nancy J.,MARCEAU Francois,ADAM Albert
- Journal of pharmacological sciences 99(1), 6-38, 2005-09-20
- … The interest of the various components of this multi-protein system is explained in part by the multiplicity of its pharmacological activities, mediated not only by kinins and their receptors, but also by their precursors and their activators and the metallopeptidases and the antiproteases that limit their activities. …
- NAID 10025729940
- P10-04 Changes Detected in Plasma Antiproteases in Paraquat Poisoned Rats Using Micro Two-Dimensional Electrophoretic Analysis
- SAKAGUCHI Kazuko,KAGEYAMA Kouichi,ORITO Kensuke,SHIRAI Mitsuyuki,AKAHORI Fumiaki
- Journal of toxicological sciences 26(4), 248, 2001-10-17
- NAID 110001807005
Related Links
- TY - CHAP T1 - Antiproteases A1 - Taggart,Clifford AU - Taggart,Clifford PB - Taylor and Francis PY - 2005/4 Y1 - 2005/4 M3 - Chapter SN - 9780824723118 BT - Chronic Obstructive Pulmonary Disease Cellular and Molecular ...
- Antiproteases Sophie Réhault … show all 1 hide Download Book (6,834 KB) As a courtesy to our readers the eBook is provided DRM-free. However, please note that Springer uses effective methods and state-of-the art Close ...
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