- 関
- antihypoxia
English Journal
- Modular Synthesis of Cell-Permeating 2-Ketoglutarate Esters.
- Zengeya TT1, Kulkarni RA1, Meier JL1.
- Organic letters.Org Lett.2015 Apr 27. [Epub ahead of print]
- Cell-permeating esters of 2-ketoglutarate (2-KG) have been synthesized through a convergent sequence from two modules in two and three steps, respectively. This route provides access to a full series of mono- and disubstituted 2-KG esters, enabling us to define the effect of regioisomeric masking on
- PMID 25915096
- Antihypoxic activity of cycloprolylglycine analogs.
- Kolyasnikova KN1, Nazarova GA, Gudasheva TA, Voronina TA, Seredenin SB.
- Bulletin of experimental biology and medicine.Bull Exp Biol Med.2015 Feb;158(4):458-60. doi: 10.1007/s10517-015-2784-1. Epub 2015 Feb 24.
- We studied antihypoxic activity of analogs of endogenous cyclic dipeptide cycloprolylglycine in a mouse model of normobaric hypoxia with hypercapnia and found that antixypoxic effect depends on the structure of the substance. It was shown that different pharmacophores are responsible for the antihyp
- PMID 25708325
- Purification of polysaccharides from Cordyceps militaris and their anti‑hypoxic effect.
- Dong Y1, Hu S1, Liu C1, Meng Q1, Song J1, Lu J1, Cheng Y1, Gao C1, Liu Y1, Wang D1, Teng L1.
- Molecular medicine reports.Mol Med Rep.2015 Feb;11(2):1312-7. doi: 10.3892/mmr.2014.2786. Epub 2014 Oct 27.
- Acute mountain sickness, one of the most common altitude diseases, causes lung and brain injury. The present study aimed to investigate the anti‑hypoxic effect of purified polysaccharides extracted from Cordyceps militaris. The aqueous extract of Cordyceps militaris was purified progressively th
- PMID 25351532
Japanese Journal
- Effects of antihypoxic and neuroprotective drug, lubeluzole, on repolarization phase of canine heart assessed by monophasic action potential recording
- Studies on Cognitive Enhancing Agents. III・ Antiamnestic and Antihypoxic Activities of a Series of 1-Bicycloaryl-2-(ω-aminoalkoxy)ethanols
- 小野 哲,山藤 哲夫,茶木 久晃,森田 肇,藤堂 洋三,岡田 直美,前川 睦子,北村 和則,田井 賢,成田 弘和
- Chemical & pharmaceutical bulletin 43(9), 1492-1496, 1995-09-15
- … 2-(2-Aminoethoxy)-1-hydroxyethyl derivatives of bicyclic arenes) naphthalene, thianaphthene, benzofuran, and indole) were prepared and screened for antiamnestic (AA) and antihypoxic (AH) activities which were evaluated by measuring the reversing potency in electroconvulsion-induced amnesia and the protective effect against hypoxia, respectively, in mice. …
- NAID 110003631691
- Studies on Cognitive Enhancing Agents. II. Antiamnestic and Antihypoxic Activities of 1-Aryl-2-(2-aminoethoxy)ethanols
- 小野 哲,山藤 哲夫,茶木 久晃,森田 肇,藤堂 洋三,前川 睦子,北村 和則,田井 賢,成田 弘和
- Chemical & pharmaceutical bulletin 43(9), 1488-1491, 1995-09-15
- … A series of 2-(2-aminoethoxy)-1-phenylethanols having a variety of N- and phenyl-substitution patterns as well as 5- and 6-membered heteroaryl counterparts of our prototype compound 1 (2-(2-dimethylaminoethoxy)-1-phenylethanol) have been prepared and evaluated for antiamnestic and antihypoxic activities. …
- NAID 110003631690
Related Links
- ANTIHYPOXIC AGENT This invention refers to a pharmaceutical agent for the treatment of diseases related to hypoxic and ischaemic disturbances of cerebral functions, such as: acute and chronic impairment of cerebral ...
- New thienyldihydropyridines were synthesized according to Hantzsch's method. The antihypoxic activity of these compounds was compared with that of three reference phenyldihydropyridines by means of the skin conductance ...
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- 関
- antihypoxic
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- 英
- antihypoxia、antihypoxic