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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/06/01 08:27:45」(JST)
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Amphotropism or amphotropic indicates that a pathogen like a virus or a bacterium has a wide host range and can infect more than one species or cell culture line.
See also
- Tropism, a list of tropisms
- Ecotropism, indicating a narrow host range
English Journal
- C3H strain of mouse mammary tumour virus, like GR strain, infects human mammary epithelial cells, albeit less efficiently than murine mammary epithelial cells.
- Konstantoulas CJ1, Indik S1.
- The Journal of general virology.J Gen Virol.2015 Mar;96(Pt 3):650-62. doi: 10.1099/jgv.0.000006. Epub 2014 Dec 9.
- Mouse mammary tumour virus (MMTV) is a member of the genus Betaretrovirus, infects rodent cells and uses mouse tranferrin receptor 1 for cell entry. Several MMTV strains have been shown to productively infect, in addition to murine cells, various heterologous cell lines including those of human orig
- PMID 25491421
- A sorting signal suppresses IFITM1 restriction of viral entry.
- Li K1, Jia R2, Li M1, Zheng YM1, Miao C1, Yao Y2, Ji HL3, Geng Y2, Qiao W2, Albritton LM4, Liang C5, Liu SL6.
- The Journal of biological chemistry.J Biol Chem.2015 Feb 13;290(7):4248-59. doi: 10.1074/jbc.M114.630780. Epub 2014 Dec 19.
- The interferon-induced transmembrane proteins (IFITMs) broadly inhibit virus infections, particularly at the viral entry level. However, despite this shared ability to inhibit fusion, IFITMs differ in the potency and breadth of viruses restricted, an anomaly that is not fully understood. Here, we sh
- PMID 25527505
- Intravenous administration of retroviral replicating vector, Toca 511, demonstrates therapeutic efficacy in orthotopic immune-competent mouse glioma model.
- Huang TT1, Parab S, Burnett R, Diago O, Ostertag D, Hofman FM, Espinoza FL, Martin B, Ibañez CE, Kasahara N, Gruber HE, Pertschuk D, Jolly DJ, Robbins JM.
- Human gene therapy.Hum Gene Ther.2015 Feb;26(2):82-93. doi: 10.1089/hum.2014.100. Epub 2015 Jan 19.
- Toca 511 (vocimagene amiretrorepvec), a nonlytic, amphotropic retroviral replicating vector (RRV), encodes and delivers a functionally optimized yeast cytosine deaminase (CD) gene to tumors. In orthotopic glioma models treated with Toca 511 and 5-fluorocytosine (5-FC) the CD enzyme within infected c
- PMID 25419577
Japanese Journal
- Infection of XC Cells by MLVs and Ebola Virus Is Endosome-Dependent but Acidification-Independent.
- Kamiyama Haruka,Kakoki Katsura,Yoshii Hiroaki,Iwao Masatomo,Igawa Tsukasa,Sakai Hideki,Hayashi Hideki,Matsuyama Toshifumi,Yamamoto Naoki,Kubo Yoshinao
- PLoS One 6(10), e26180, 2011-10-12
- … Inhibitors of endosome acidification or cathepsin proteases attenuated infections mediated by envelope proteins of xenotropic murine leukemia virus-related virus (XMRV) and Ebola virus, as well as ecotropic, amphotropic, polytropic, and xenotropic murine leukemia viruses (MLVs), indicating that infections by these viruses occur through acidic endosomes and require cathepsin proteases in the susceptible cells such as TE671 cells. …
- NAID 120003477574
- Color Tunable Novel Amphotropic Liquid Crystalline Acrylate End-capped with a Cholesteryl Group
- HSIEH Feng-Min,FANG Hau,LIU Jui-Hsiang
- Chemistry letters 39(5), 485-487, 2010-05-05
- NAID 10027180448
Related Links
- の細胞にも感染性を示す両指向性(amphotropic)のレト ロウイルスが分離されることがあるが,このタイプのウイ ルスはその遺伝子塩基配列の点でも生物活性の点でも,内 在性polytropicウイルスや組換え型MCFウイルスとは全
- a virus usually associated with retroviruses that may not produce disease in its natural host but does replicate in tissue culture cells of host species ... amphotropic virus A virus that recognises receptors and replicates in ...
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- 英
- amphotropic
- 関
- アンホトロピック、両種指向性
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- 英
- amphotropic
- 関
- アンホトロピック、広宿主性
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- 英
- amphotropic
- 関
- 広宿主性、両種指向性