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a fibrous amphibole; used for making fireproof articles; inhaling fibers can cause asbestosis or lung cancer

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1. 石綿肺症 asbestosis
2. 悪性中皮腫の疫学 epidemiology of malignant mesothelioma
3. 悪性腹膜中皮腫：疫学、危険因子、臨床所見、診断、および病期分類 malignant peritoneal mesothelioma epidemiology risk factors clinical presentation diagnosis and staging
4. 肺癌における喫煙およびその他の危険因子 cigarette smoking and other risk factors for lung cancer
5. 胸水中の好酸球増加 pleural fluid eosinophilia

Evaluation of anti-nuclear antibodies and kidney pathology in Lewis rats following exposure to Libby amphibole asbestos.

Salazar KD, Copeland CB, Wood CE, Schmid JE, Luebke RW.SourceToxicity Pathways Branch, Integrated Risk Information System Division, National Center for Environmental Assessment, Office of Research and Development, US Environmental Protection Agency (USEPA) , Washington, DC , USA.
Journal of immunotoxicology.J Immunotoxicol.2012 Dec 21. [Epub ahead of print]
Abstract The prevalence of anti-nuclear antibodies (ANA) and self-reported systemic autoimmune diseases were increased in residents of Libby, MT, as was the incidence of ANA in Lewis rats exposed to Libby amphibole (LA) asbestos. However, rats induced to develop rheumatoid arthritis (RA) did not d
PMID 23256773

Distinct affinity of nuclear proteins to the surface of chrysotile and crocidolite.

Kubo Y, Takenaka H, Nagai H, Toyokuni S.SourceDepartment of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.
Journal of clinical biochemistry and nutrition.J Clin Biochem Nutr.2012 Nov;51(3):221-6. doi: 10.3164/jcbn.12-39. Epub 2012 Sep 5.
The inhalation of asbestos is a risk factor for the development of malignant mesothelioma and lung cancer. Based on the broad surface area of asbestos fibers and their ability to enter the cytoplasm and nuclei of cells, it was hypothesized that proteins that adsorb onto the fiber surface play a role
PMID 23170051

Jiang L, Akatsuka S, Nagai H, Chew SH, Ohara H, Okazaki Y, Yamashita Y, Yoshikawa Y, Yasui H, Ikuta K, Sasaki K, Kohgo Y, Hirano S, Shinohara Y, Kohyama N, Takahashi T, Toyokuni S.SourceDepartment of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.
The Journal of pathology.J Pathol.2012 Nov;228(3):366-77. doi: 10.1002/path.4075. Epub 2012 Aug 2.
Exposure to asbestos is a risk for malignant mesothelioma (MM) in humans. Among the commercially used types of asbestos (chrysotile, crocidolite, and amosite), the carcinogenicity of chrysotile is not fully appreciated. Here, we show that all three asbestos types similarly induced MM in the rat peri
PMID 22864872