出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/12/03 21:27:36」(JST)
| Colitis | |
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A micrograph demonstrating cryptitis, a microscopic correlate of colitis. H&E stain.
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| Classification and external resources | |
| Specialty | Gastroenterology |
| ICD-10 | K50 - K52 |
| ICD-9-CM | 556.9 |
| OMIM | 191390 |
| DiseasesDB | 31340 |
| MedlinePlus | 001125 |
| eMedicine | ped/435 |
| MeSH | C06.405.205.265 |
Colitis (pl. colitides) refers to an inflammation of the colon.
Colitis may be acute and self-limited or chronic, i.e. persistent, and broadly fits into the category of digestive diseases.
In a medical context, the label colitis (without qualification) is used if:
The signs and symptoms of colitis are quite variable and dependent on the cause of the given colitis and factors that modify its course and severity.
Symptoms of colitis may include: abdominal pain, recurring diarrhea, pus or blood in stools, urgency, bloating, fatigue, loss of appetite, vomiting, and unexplained weight loss.[1][2]
More severe symptoms may include: shortness of breath, a fast or irregular heartbeat, and fever.[1][2]
Other less non-specific symptoms that may accompany colitis include: arthritis; mouth ulcers; painful, red and swollen skin; and irritated, red eyes.[1][2]
Signs seen on colonoscopy include: colonic mucosal erythema (redness of the inner surface of the colon), ulcers, and bleeding.[medical citation needed]
Symptoms suggestive of colitis are worked-up by obtaining the medical history, a physical examination and laboratory tests (CBC, electrolytes, stool culture and sensitivity, stool ova and parasites et cetera). Additional tests may include medical imaging (e.g. abdominal computed tomography, abdominal X-rays) and an examination with a camera inserted into the rectum (sigmoidoscopy, colonoscopy).
There are many types of colitis. They are usually classified by the cause.
Types of colitis include:
A well-known subtype of infectious colitis is Clostridium difficile colitis,[3] which is informally abbreviated as "c diff colitis". It classically forms pseudomembranes and is often referred to as pseudomembranous colitis, which is its (non-specific) histomorphologic description.
Enterohemorrhagic colitis may be caused by Shiga toxin in Shigella dysenteriae or Shigatoxigenic group of Escherichia coli (STEC), which includes serotype O157:H7 and other enterohemorrhagic E. coli.[4]
Parasitic infections, like those caused by Entamoeba histolytica, can also cause colitis.
Indeterminate colitis is the classification for colitis that has features of both Crohn's disease and ulcerative colitis.[5] Indeterminate colitis' behaviour is usually closer to ulcerative colitis than Crohn's disease.[6]
Atypical colitis is a phrase that is occasionally used by physicians for a colitis that does not conform to criteria for accepted types of colitis. It is not an accepted diagnosis per se and, as such, a colitis that cannot be definitively classified.
Some people may be admitted into the hospital following the colonoscopy depending on results. It is sometimes necessary to get the patient started on a steroid to speed up the healing of the colon. It may also be necessary to get the patient hydrated from the fluid loss and iron replaced from the loss of blood. Beyond a hospital stay, the patient will be put on a daily medication which they will continuously take since this is a chronic yet manageable condition. The medication can be an anti-inflammatory or an immunosuppressant. There are many different types of medication used and the doctor will prescribe the one they see fit. If the patient doesn't respond, new medications will be tried until there is a good fit. Moreover, several studies recently have found significant relationship between colitis and dairy allergy (including: cow milk, cow milk UHT and casein) [7] [8] [9] [10] suggesting some patients may benefit of an elimination diet.
| Wikimedia Commons has media related to Colitis. |
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| リンク元 | 「intestinal amebiasis」 |
| 関連記事 | 「amoebic」 |
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