WordNet

partial or total loss of sight without pathology of the eye; caused by disease of optic nerve or retina or brain

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/03/10 10:28:26」(JST)

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Amaurosis (Greek meaning darkening, dark, or obscure) is vision loss or weakness that occurs without an apparent lesion affecting the eye.^[1] It may result from either a medical condition or from excess acceleration, as in flight. The term is the same as the Latin gutta serena.

Types[edit]

Leber's congenital amaurosis is an inherited disease resulting in optic atrophy and secondary severe vision loss or blindness. It was first described by Theodore Leber in the 19th century.

Amaurosis fugax (Latin: fugax meaning fleeting) is a temporary loss of vision in one eye caused by decreased blood flow (ischemia) to the retina. It may also be caused by embolization from atherosclerotic plaques in the ipsilateral (same side) internal carotid artery. It is a type of transient ischaemic attack (TIA). Those experiencing amaurosis usually experience complete symptom resolution within a few minutes. In a small minority of those who experience amaurosis, stroke or permanent vision loss results. Diabetes, hypertension and smoking are factors known to increase the risks of suffering this condition. It also can be the result of surgical repair to the mitral valve, when very small emboli may break away from the site of the repair, while the patient's tissue grows to cover the plastic annuloplasty band.

Quinidine toxicity can lead to cinchonism and also to quinine amaurosis.

In Animals[edit]

This condition can also occur in ruminants suffering from a vitamin B₁ (thiamine) deficiency due to thiamine-related cerebrocortical necrosis (CCN).

Management[edit]

Those experiencing amaurosis are usually advised to consult a physician immediately as any form of vision loss, even if temporary, is a symptom that may indicate the presence of a serious ocular or systemic problem.

References[edit]

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1. 一過性黒内障（一過性単眼または両眼視力低下） amaurosis fugax transient monocular or binocular visual loss
2. 巨細胞（側頭）動脈炎の臨床症状 clinical manifestations of giant cell temporal arteritis
3. 急性持続性視力喪失が認められた成人に対するアプローチ approach to the adult with acute persistent visual loss
4. 網膜中心動脈閉塞症および網膜動脈分枝閉塞症 central and branch retinal artery occlusion
5. 網膜色素変性症：治療 retinitis pigmentosa treatment

English Journal

Impediment of selenite-induced cataract in rats by combinatorial drug laden liposomal preparation.

Huang C, Li C, Muhemaitia P.
The Libyan journal of medicine. 2019 12;14(1)1548252.
Cataract is the leading cause of blindness globally with surgery being the only form of treatment. But cataract surgery is accompanied by complications, chiefly intra-ocular infections. Hence, preventive nanoformulations may be extremely beneficial. In the present study, novel chitosan-coated liposo
PMID 30460877

Identification of hsa-mir-34a, hsa-mir-124, and hsa-mir-204 as signatures for cataract.

Wei YL, Sun H.
Journal of cellular physiology. 2019 Jul;234(7)10709-10717.
Cataract, one of the common age-related diseases that remains the leading cause of blindness worldwide. There have been studies pertaining to microRNA (miRNA) effects on cataract pathogenesis. However, the results were different from each other due to the influence of sequencing platform, sample sel
PMID 30478927

Twins and neurodevelopmental outcomes: the effect of IVF, fetal growth restriction, and preterm birth.

Briana DD, Malamitsi-Puchner A.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 2019 Jul;32(13)2256-2261.
This invited review aimed at presenting the evidence concerning neurodevelopmental outcomes, particularly cerebral palsy (CP), motor disability, cognitive impairment, mental retardation, any major disability, blindness and deafness in cases of twins, conceived after in vitro fertilization, presentin
PMID 29307249