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Lavandera JV, Fossati M, Azcurra J, Batlle A, Buzaleh AM.SourceHospital de Clinicas José de San Martin, University of Buenos Aires Centro de Investigaciones sobre Porfirinas y Porfirias (CIPYP), CONICET Argentina.
Cellular and molecular biology (Noisy-le-Grand, France).Cell Mol Biol (Noisy-le-grand).2009 Feb 16;55(1):23-8.
The N-methyl-diethyl-aspartate (NMDA) receptor has been reported to play an important role in several acute and chronic neuropathologic syndromes. 5-aminolevulinic acid (ALA) accumulates in acute porphyrias due to a deficiency in the heme biosynthetic pathway. Considering that glutamate uptake inhib
PMID 19267998

The effect of haem biosynthesis inhibitors and inducers on intestinal iron absorption and liver haem biosynthetic enzyme activities.

Laftah AH, Simpson RJ, Peters TJ, Raja KB.SourceNutrition Sciences Division, King's College London, Franklin Wilkins Building, Stamford Street, London SE1 9NH, UK.
Toxicology and applied pharmacology.Toxicol Appl Pharmacol.2008 Jun 15;229(3):273-80. doi: 10.1016/j.taap.2008.01.027. Epub 2008 Feb 7.
The relation between haem biosynthesis and intestinal iron absorption is not well understood, we therefore investigated the effect of compounds that alter haem metabolism on duodenal iron absorption. CD1 mice were treated with either an inhibitor (succinyl acetone (SA)) or stimulator (2-allyl-2-isop
PMID 18384829

Evaluation of the enantioselective antiallodynic and pharmacokinetic profile of propylisopropylacetamide, a chiral isomer of valproic acid amide.

Kaufmann D, Yagen B, Minert A, Tal M, Devor M, Bialer M.SourceDepartment of Pharmaceutics, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.
Neuropharmacology.Neuropharmacology.2008 Mar;54(4):699-707. doi: 10.1016/j.neuropharm.2007.11.020. Epub 2007 Dec 8.
Propylisopropylacetamide (PID) is a chiral CNS-active constitutional isomer of valpromide, the amide derivative of the major antiepileptic drug valproic acid (VPA). The purpose of this work was: a) To evaluate enantiospecific activity of PID on tactile allodynia in the Chung (spinal nerve ligation,
PMID 18201732

δ-aminolevulinate synthetases in the liver cytosol fraction and mitochondria of mice treated with allylisopropylacetamide and 3,5-dicarbethoxy-1,4-dihydrocollidine