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1. 造血細胞移植後の再発の予防および治療のための免疫療法 immunotherapy for the prevention and treatment of relapse following hematopoietic cell transplantation
2. 肺移植：レシピエント選定のための一般的ガイドライン lung transplantation general guidelines for recipient selection
3. 急性呼吸窮迫症候群：成人における疫学、病態生理、病理、および病因 acute respiratory distress syndrome epidemiology pathophysiology pathology and etiology in adults
4. 原発性免疫不全症のための造血細胞移植 hematopoietic cell transplantation for primary immunodeficiency
5. BおよびTリンパ球の正常な発生 normal b and t lymphocyte development

English Journal

Both positive and negative effects on immune responses by expression of a second class II MHC molecule.

Ni PP1, Wang Y1, Allen PM2.
Molecular immunology.Mol Immunol.2014 Nov;62(1):199-208. doi: 10.1016/j.molimm.2014.06.024. Epub 2014 Jul 10.
It is perplexing why vertebrates express a limited number of major histocompatibility complex (MHC) molecules when theoretically, having a greater repertoire of MHC molecules would increase the number of epitopes presented, thereby enhancing thymic selection and T cell response to pathogens. It is p
PMID 25016574

Stable mixed hematopoietic chimerism permits tolerance of vascularized composite allografts across a full major histocompatibility mismatch in swine.

Mathes DW1, Solari MG, Gazelle GS, Butler PE, Wu A, Nazzal A, Nielsen GP, Huang CA, Sachs DH, Lee WP, Randolph MA.
Transplant international : official journal of the European Society for Organ Transplantation.Transpl Int.2014 Oct;27(10):1086-96. doi: 10.1111/tri.12380. Epub 2014 Aug 28.
This study tested the hypothesis that vascularized composite allografts (VCA) could be accepted in a robust model of hematopoietic chimerism by injecting allogeneic bone marrow cells (BMC) into swine fetuses. Outbred Yorkshire sows and boars were screened to ensure the absence of the major histocomp
PMID 24963743

Autologous apoptotic cells preceding transplantation enhance survival in lethal murine graft-versus-host models.

Florek M1, Sega EI1, Leveson-Gower DB1, Baker J1, Müller AM2, Schneidawind D1, Meyer E1, Negrin RS1.
Blood.Blood.2014 Sep 11;124(11):1832-42. doi: 10.1182/blood-2014-02-555128. Epub 2014 Jul 16.
Acute graft-versus-host disease (GVHD) is induced by alloreactivity of donor T cells toward host antigens presented on antigen-presenting cells (APCs). Apoptotic cells are capable of inducing tolerance by altering APC maturation. Apoptosis can be induced by extracorporeal photopheresis (ECP). We dem
PMID 25030062

Induction of natural killer T cell-dependent alloreactivity by administration of granulocyte colony-stimulating factor after bone marrow transplantation