WordNet
- a therapist who makes suffering more endurable
English Journal
- Medical futility in the care of non-competent terminally ill patient: Nursing perspectives and responsibilities.
- Scanlon A, Murphy M.Author information La Trobe University/Austin Health Clinical School of Nursing, Faculty of Health Sciences, La Trobe University, Melbourne, Australia; Department of Neurosurgery, Austin Health, Heidelberg, Australia. Electronic address: a.scanlon@latrobe.edu.au.AbstractBACKGROUND: Debate continues on the use of medical technology to prolong life independent of the quality of the outcomes. As a consequence, acute care nurses often find themselves in situations where they are asked to carry out physician's orders, in the context of a patient's deteriorating condition, which may be at odds with professional and personal ethical standards. This can cause nurses to become distressed when struggling with the ethical dilemmas involved with medical futility.
- Australian critical care : official journal of the Confederation of Australian Critical Care Nurses.Aust Crit Care.2012 Dec 3. pii: S1036-7314(12)00150-6. doi: 10.1016/j.aucc.2012.10.003. [Epub ahead of print]
- BACKGROUND: Debate continues on the use of medical technology to prolong life independent of the quality of the outcomes. As a consequence, acute care nurses often find themselves in situations where they are asked to carry out physician's orders, in the context of a patient's deteriorating conditio
- PMID 23218919
- Arctigenin alleviates ER stress via activating AMPK.
- Gu Y, Sun XX, Ye JM, He L, Yan SS, Zhang HH, Hu LH, Yuan JY, Yu Q.Author information Department of Tumor Pharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, China.AbstractAIM: To investigate the protective effects of arctigenin (ATG), a phenylpropanoid dibenzylbutyrolactone lignan from Arctium lappa L (Compositae), against ER stress in vitro and the underlying mechanisms.
- Acta pharmacologica Sinica.Acta Pharmacol Sin.2012 Jul;33(7):941-52. doi: 10.1038/aps.2012.60. Epub 2012 Jun 18.
- AIM: To investigate the protective effects of arctigenin (ATG), a phenylpropanoid dibenzylbutyrolactone lignan from Arctium lappa L (Compositae), against ER stress in vitro and the underlying mechanisms.METHODS: A cell-based screening assay for ER stress regulators was established. Cell viability wa
- PMID 22705729
- Mitochondrial ('mild') uncoupling and ROS production: physiologically relevant or not?
- Shabalina IG, Nedergaard J.Author information The Wenner-Gren Institute, The Arrhenius Laboratories F3, Stockholm University, SE-106 91 Stockholm, Sweden. irina.shabalina@wgi.su.seAbstractDuring the last decade, the possibility that 'mild' uncoupling could be protective against oxidative damage by diminishing ROS (reactive oxygen species) production has attracted much interest. In the present paper, we briefly examine the evidence for this possibility. It is only ROS production from succinate under reverse electron-flow conditions that is sensitive to membrane potential fluctuations, and so only this type of ROS production could be affected; however, the conditions under which succinate-supported ROS production is observed include succinate concentrations that are supraphysiological. Any decrease in membrane potential, even 'mild uncoupling', must necessarily lead to large increases in respiration, i.e. it must be markedly thermogenic. Mitochondria within cells are normally ATP-producing and thus already have a diminished membrane potential, and treatment of cells, organs or animals with small amounts of artificial uncoupler does not seem to have beneficial effects that are explainable via reduced ROS production. Although it has been suggested that members of the uncoupling protein family (UCP1, UCP2 and UCP3) may mediate a mild uncoupling, present evidence does not unequivocally support such an effect, e.g. the absence of the truly uncoupling protein UCP1 is not associated with increased oxidative damage. Thus present evidence does not support mild uncoupling as a physiologically relevant alleviator of oxidative damage.
- Biochemical Society transactions.Biochem Soc Trans.2011 Oct;39(5):1305-9. doi: 10.1042/BST0391305.
- During the last decade, the possibility that 'mild' uncoupling could be protective against oxidative damage by diminishing ROS (reactive oxygen species) production has attracted much interest. In the present paper, we briefly examine the evidence for this possibility. It is only ROS production from
- PMID 21936806
Japanese Journal
- Functional Characterization of Arabidopsis Calreticulin1a : A Key Alleviator of Endoplasmic Reticulum Stress
- Christensen Anna,Svensson Karin,Persson Staffan [他],JUNG Joanna,MICHALAK Marek,WIDELL Susanne,SOMMARIN Marianne
- Plant and cell physiology 49(6), 912-924, 2008-06-01
- NAID 10027331794
- 緩和滲炭における材的諸性について
- 熊野御堂 晋
- 熊野工業高等専門学校紀要 1, 7-12, 1972-12-20
- … Therefore, the author conducted an investigation seeking out some preventive methods, using Fe-Si alloys as an alleviator under various conditions of experiments, results of which are summarised as follows; …
- NAID 110004814178
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- Photography does not merely pander to the gratification of earthly vanity, but is an alleviator of human misery.
- alleviatorとは。意味や和訳。[名]1 軽減者；緩和物，緩和剤.2 （水管などの）水撃緩和装置. - goo英和辞書は14万項目以上を収録し、発音、音声、慣用句、例文が分かる英和辞書です。
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