WordNet

turn basic and less acidic; "the solution alkalized" (同)alkalise, alkalify, basify

English Journal

Development, optimization, and characterization of a novel tea tree oil nanogel using response surface methodology.

Sinha P1, Srivastava S1, Mishra N1, Singh DK2, Luqman S2, Chanda D2, Yadav NP1.
Drug development and industrial pharmacy.Drug Dev Ind Pharm.2016 Feb 15:1-12. [Epub ahead of print]
Purpose To develop and optimize nanoemulsion (NE)-based emulgel (EG) formulation as a potential vehicle for topical delivery of tea tree oil (TTO). Methodology Central composite design was adopted for optimizing the processing conditions for NE preparation by high energy emulsification method viz. s
PMID 26821208

Investigation of the combined effect of MgO and PEG on the release profile of mefenamic acid prepared via hot-melt extrusion techniques.

Alshehri SM1, Tiwari RV1, Alsulays BB2, Ashour EA1, Alshetaili AS2, Almutairy B1, Park JB3, Morott J1, Sandhu B4, Majumdar S1, Repka MA1,5.
Pharmaceutical development and technology.Pharm Dev Technol.2016 Jan 29:1-14. [Epub ahead of print]
This study aimed to investigate the combined effect of magnesium oxide (MgO) as an alkalizer and polyethylene glycol (PEG) as a plasticizer and wetting agent in the presence of Kollidon® 12 PF and 17 PF polymer carriers on the release profile of mefenamic acid (MA), which was prepared via hot-melt
PMID 26821841

Enhanced dissolution and oral bioavailability of valsartan solid dispersions prepared by a freeze-drying technique using hydrophilic polymers.

Xu WJ1, Xie HJ2, Cao QR1, Shi LL1, Cao Y1, Zhu XY1, Cui JH1.
Drug delivery.Drug Deliv.2016 Jan;23(1):41-8. doi: 10.3109/10717544.2014.903012. Epub 2015 Sep 4.
This study aimed to improve the dissolution rate and oral bioavailability of valsartan (VAL), a poorly soluble drug using solid dispersions (SDs). The SDs were prepared by a freeze-drying technique with polyethylene glycol 6000 (PEG6000) and hydroxypropylmethylcellulose (HPMC 100KV) as hydrophilic p
PMID 24735247