WordNet

use recreational drugs (同)do drugs
administer a drug to; "They drugged the kidnapped tourist" (同)dose
a substance that is used as a medicine or narcotic
relating to or containing an alkali; having a pH greater than 7; "alkaline soils derived from chalk or limestone" (同)alkalic
a mixture of soluble salts found in arid soils and some bodies of water; detrimental to agriculture

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FLLL12 induces apoptosis in lung cancer cells through a p53/p73-independent but death receptor 5-dependent pathway.

Haque A1, Rahman MA1, Fuchs JR2, Chen ZG1, Khuri FR1, Shin DM1, Amin AR3.
Cancer letters.Cancer Lett.2015 Jul 28;363(2):166-75. doi: 10.1016/j.canlet.2015.04.017. Epub 2015 Apr 24.
Unlike chemotherapy drugs, the safety of natural compounds such as curcumin has been well established. However, the potential use of curcumin in cancer has been compromised by its low bioavailability, limited tissue distribution and rapid biotransformation leading to low in vivo efficacy. To circumv
PMID 25917567

Absence of Liver Toxicity in Perampanel-Treated Subjects: Pooled results from partial seizure phase III perampanel clinical studies.

Laurenza A1, Yang H2, Williams B3, Zhou S4, Ferry J5.
Epilepsy research.Epilepsy Res.2015 Jul;113:76-85. doi: 10.1016/j.eplepsyres.2015.03.005. Epub 2015 Mar 20.
OBJECTIVE: The liver plays a major role in the metabolism and elimination of many antiepileptic drugs (AEDs), including perampanel. Some of the metabolites identified for perampanel are likely formed via reactive intermediates, which have the potential to covalently bind to protein and cause idiosyn
PMID 25986193

Utilizing a high-throughput microfluidic platform to study hypoxia-driven mesenchymal-mode cell migration.

Zhang Y1, Wen J, Zhou L, Qin L.
Integrative biology : quantitative biosciences from nano to macro.Integr Biol (Camb).2015 Jun 8;7(6):672-80. doi: 10.1039/c5ib00059a. Epub 2015 May 12.
Hypoxia is a critical microenvironment in tumor pathogenesis. There is a close relationship between hypoxia, tumor metastasis and poor prognosis. Hypoxia has been shown to induce epithelial-mesenchymal transition and high levels of lactic acid production, through which cancer cells gain migratory ca
PMID 25965948