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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/08/06 11:11:57」(JST)
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Algestone acetophenide
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Identifiers |
CAS Registry Number
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24356-94-3 N |
ChEBI |
CHEBI:49327 Y |
ChemSpider |
4447595 Y |
InChI
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InChI=1S/C29H36O4/c1-18(30)29-25(32-28(4,33-29)19-8-6-5-7-9-19)17-24-22-11-10-20-16-21(31)12-14-26(20,2)23(22)13-15-27(24,29)3/h5-9,16,22-25H,10-15,17H2,1-4H3/t22-,23+,24+,25-,26+,27+,28-,29-/m1/s1 Y
Key: AHBKIEXBQNRDNL-FVCOMRFXSA-N Y
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InChI=1/C29H36O4/c1-18(30)29-25(32-28(4,33-29)19-8-6-5-7-9-19)17-24-22-11-10-20-16-21(31)12-14-26(20,2)23(22)13-15-27(24,29)3/h5-9,16,22-25H,10-15,17H2,1-4H3/t22-,23+,24+,25-,26+,27+,28-,29-/m1/s1
Key: AHBKIEXBQNRDNL-FVCOMRFXBW
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Jmol-3D images |
Image |
PubChem |
5284538 |
SMILES
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O=C(C)[C@]25O[C@@](O[C@@H]5C[C@H]1[C@H]4[C@H](CC[C@@]12C)[C@@]3(/C(=C\C(=O)CC3)CC4)C)(c6ccccc6)C
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Properties |
Chemical formula
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C29H36O4 |
Molar mass |
448.59 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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N verify (what is: Y/N?) |
Infobox references |
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Algestone acetophenide is a pregnane steroid. It is the ketal formed between Algestone and acetophenone.
References
- Algestone acetophenide at www.reference.md.
Progestogenics
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Receptor
(ligands) |
PR
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Agonists
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Mixed (SPRMs)
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- Asoprisnil
- Asoprisnil ecamate
- Gestrinone
- J1042
- LG-120,838
- Telapristone; Antagonistic: Mifepristone
- Org-31710
- Org-33628
- Ulipristal acetate
- ZK-137,316
- ZK-230,211
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Antagonists
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- 3α-Hydroxytibolone
- 3β-Hydroxytibolone
- Aglepristone
- BAY-1002670
- Lilopristone
- Lonaprisan
- Onapristone
- Toripristone
- Vilaprisan
- ZM-150,271
- ZM-172,406
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Enzyme |
Modulators
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- 20,22-desmolase, 17α-hydroxylase/17,20-lyase, 3β-HSD, and 21-hydroxylase) (see also Steroid hormone metabolism modulators)
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Others |
Precursors/prohormones
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- Cholesterol
- 22R-Hydroxycholesterol
- 20α,22R-Dihydroxycholesterol
- Pregnenolone
- Pregnenolone sulfate
- 17-Hydroxypregnenolone
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Indirect
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- Antigonadotropins (e.g., estrogens, progestogens, prolactin)
- GnRH agonists (e,g, GnRH, leuprorelin)
- GnRH antagonists (e.g., cetrorelix)
- Gonadotropins (e.g., FSH, hCG, LH)
- Kisspeptin
- Plasma proteins (ABP, albumin, SHBG)
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See also: Androgenics • Estrogenics • Glucocorticoids • Mineralocorticoids
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English Journal
- Comparison of two regimens of a monthly injectable contraceptive containing dihydroxyprogesterone acetophenide and estradiol enanthate.
- Coutinho EM1, Spinola P, Athayde C, Noronha CF, de Melo NR, Cabral ZA, Almeida JA, da Silva BL, Neto JS, Rumi DO.
- Contraception.Contraception.2006 Mar;73(3):249-52. Epub 2005 Oct 20.
- INTRODUCTION: This study compared two regimens of a monthly injectable contraceptive containing dihydroxyprogesterone acetophenide 150 mg and estradiol enanthate 10 mg (Perlutan) over 12 cycles of use.METHODS: Three hundred sixty-five adolescents were randomized into two groups. The patients in Grou
- PMID 16472564
- Efficacy, acceptability, and clinical effects of a low-dose injectable contraceptive combination of dihydroxyprogesterone acetophenide and estradiol enanthate.
- Coutinho EM1, Spinola P, Tomaz G, Morais K, Nassar de Souza R, Sabino Pinho Neto J, de Barros Leal W, Bomfim Hippolito S, D'Aurea Abranches A.
- Contraception.Contraception.2000 Apr;61(4):277-80.
- A total of 1,904 women, aged 15-38, used an injectable contraceptive combination of 90 mg dihydroxyprogesterone acetophenide with 6 mg estradiol enanthate, given once during each menstrual cycle between the 7th and 10th day, and preferably on the 8th day of the cycle, for a total of 17,576 cycles. O
- PMID 10899484
- Vaginal bleeding patterns in users of Perlutal, a once-a-month injectable contraceptive consisting of 10 mg estradiol enanthate combined with 150 mg dihydroxyprogesterone acetophenide. A trial of 5462 woman-months.
- Martínez GH1, Castañeda A, Correa JE.
- Contraception.Contraception.1998 Jul;58(1):21-7.
- Perlutal (other names: Topasel, Perlutan) is a once-a-month injectable contraceptive that contains 10 mg estradiol enanthate and 150 mg dihydroxyprogesterone acetophenide. A prospective trial was conducted in 216 women in Medellín, Colombia, over five years (5,462 woman-months) to establish the rat
- PMID 9743892
★リンクテーブル★
[★]
- 英
- algestone acetophenide