WordNet

action that makes a problem or a disease (or its symptoms) worse; "the aggravation of her condition resulted from lack of care" (同)exacerbation
unfriendly behavior that causes anger or resentment (同)irritation, provocation
an exasperated feeling of annoyance (同)exasperation
become worse or disintegrate; "His mind deteriorated"
process of changing to an inferior state (同)decline in quality, declension, worsening
a symptom of reduced quality or strength (同)impairment
the act of making something more noticeable than usual; "the dance involved a deliberate exaggeration of his awkwardness"
making to seem more important than it really is (同)overstatement, magnification
make worse; "This drug aggravates the pain" (同)aggravate, exacerbate, exasperate
grow worse; "Conditions in the slum worsened" (同)decline

PrepTutorEJDIC

悪化,深刻化 / 〈C〉《話》腹立ちの原因
…‘を'悪化させる;…‘の'品質などを低下させる / 〈人格・品質・価値などが〉悪化する,低下する
…‘を'『誇張する』,大げさに言う(考える) / 誇張する,大げさに言う
(価値・質などの)低下,悪化
〈U〉誇張,過大視 / 〈C〉誇張した表現,大げさな言い方
…‘を'いっそう悪化させる / いっそう悪化する

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/04/27 13:26:53」(JST)

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1. 全身性硬化症（強皮症）と妊娠 systemic sclerosis scleroderma and pregnancy
2. リウマチ状態に対する鍼治療 acupuncture for rheumatic conditions
3. 慢性腎臓病における代謝性アシドーシスの病因、影響、および治療 pathogenesis consequences and treatment of metabolic acidosis in chronic kidney disease
4. 冠動脈疾患および脳血管疾患における心理社会的因子 psychosocial factors in coronary and cerebral vascular disease
5. 成人における肘痛の評価 evaluation of elbow pain in adults

English Journal

Factors associated with disability and impact of tension-type headache: findings of the Korean headache survey.

Kim BS1, Chung CS, Chu MK, Chung YK, Lee CB, Kim JM.
The journal of headache and pain.J Headache Pain.2015 Dec;16:524. doi: 10.1186/s10194-015-0524-6. Epub 2015 May 4.
BACKGROUND: Although mostly mild in symptom severity, tension-type headache (TTH) can cause disability. However, factors associated with disability of TTH have been rarely reported. This study sought to assess the factors associated with TTH-related disability and impact.METHODS: We analyzed data fo
PMID 25943683

Development of animal model for Bisphosphonates-related osteonecrosis of the jaw (BRONJ).

Jang HW1, Kim JW2, Cha IH3.
Maxillofacial plastic and reconstructive surgery.Maxillofac Plast Reconstr Surg.2015 Jul 25;37(1):18. eCollection 2015.
BACKGROUND: The aim of this study is to develop a rat model of bisphosphonates-related osteonecrosis of the jaw (BRONJ) that would be verified with clinical, radiological and histological examination, and to confirm the influence of concurrent bisphosphonates and steroids use upon the occurrence and
PMID 26217648

Chronic Chagas disease with advanced cardiac complications in Japan: Case report and literature review.

Imai K1, Maeda T2, Sayama Y3, Osa M1, Mikita K1, Kurane I4, Miyahira Y5, Kawana A1, Miura S3.
Parasitology international.Parasitol Int.2015 Oct;64(5):240-2. doi: 10.1016/j.parint.2015.02.005. Epub 2015 Mar 3.
Due to the unprecedented recent increases in global migration, Chagas disease has become a global health threat and its epidemiology has drastically changed. Here we describe the first case in Japan of benznidazole treatment for chronic Chagas disease characterized by advanced cardiac complications.
PMID 25744336

Emergent cervical surgical embolectomy for extracranial internal carotid artery occlusion.

Kiyofuji S1, Inoue T, Tamura A, Saito I.
Acta neurochirurgica.Acta Neurochir (Wien).2015 Sep;157(8):1313-9. doi: 10.1007/s00701-015-2478-5. Epub 2015 Jun 23.
BACKGROUND: Acute extracranial internal carotid artery (ICA) occlusion by a huge cardiogenic embolus is rare, but can be catastrophic.METHODS: Seven patients with acute ischemic stroke due to embolic occlusion of extracranial ICA who underwent emergent cervical surgical embolectomy were retrospectiv
PMID 26095081

Japanese Journal

<研究ノート>教育入院の経験の語り --T病院に教育入院中のアトピー性皮膚炎患者へのインタビューから

いのちの未来 = The Future of Life 1, 56-74, 2016-01-15
NAID 120005694177

ウサギに認められた黒色腫の4症例

動物臨床医学 23(3), 107-110, 2016
NAID 130005125179

多発脳梗塞，脳出血を合併した僧帽弁位感染性心内膜炎に対し外科的治療により救命し得た1例

日本心臓血管外科学会雑誌 45(1), 37-40, 2016
NAID 130005124818

免疫性血小板減少症を合併した超高齢者の急性 A 型大動脈解離に対し上行弓部大動脈置換術後，基部再解離に対し再手術を施行した1例

日本心臓血管外科学会雑誌 45(1), 57-61, 2016
NAID 130005124806

「exaggerate」

　　[★]

vt.

大げさに言う、誇張する。誇大に考える、過大視する。際だたせる
(病気、状態を)悪化させる、激化させる。(器官を)肥大させる

Pulsus paradoxus may also be manifest by other conditions in which inspiration is exaggerated, including severe asthma and chronic obstructive airway disease.

Exaggerated perifollicular neovascularization with some of the new blood vessels exhibiting increased permeability.(uptodate)()

vi.

誇張した言い方をする

関: (adj.)exaggerated 誇大な、過度の。(動)異常に大きな、肥大した

関: aggravate, aggravation, deteriorate, deterioration, exacerbate, exacerbation, exaggeration, worsen

「deteriorate」

　　[★]

(de-(悪化)+ -terior(より悪く) + -ate )より一層悪くする

vi.

悪くなる、(～に)悪化する(into)。(道徳などが)低下する、堕落する。衰える

As the disease progresses and speech deteriorates communication may be helped by using computers.(病気が悪化し、発話が悪くなったとき、コンピュータの使用で会話は補助されうる)

vt.

(価値・品質など)を悪くする、悪化させる。～を悪化させる

対: (vt.)ameliorate

関: aggravate, aggravation, alter, alteration, deterioration, exacerbate, exacerbation, exaggerate, exaggeration, worsen

「deterioration」

　　[★]

n.

悪化、低下

There is even concern that rapid recovery of the platelet pool during treatment may explain subsequent deterioration in some patients's clinical course.(WCH.1559)