- 関
- aerosolize
WordNet
- in the form of ultramicroscopic solid or liquid particles dispersed or suspended in air or gas (同)aerosolised
- disperse as an aerosol; "The bacteria suspension was aerosolized" (同)aerosolise
- become dispersed as an aerosol; "the bacteria quickly aerosolised" (同)aerosolise
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/09/22 19:23:47」(JST)
[Wiki en表示]
Aerosolization is the process or act of converting some physical substance into the form of particles small and light enough to be carried on the air i.e. into an aerosol.
The term is often used in medicine to refer specifically to the production of airborne particles (e.g. tiny liquid droplets) containing infectious virus or bacteria. The infectious organism is said to be aerosolized. This can occur when an infected individual coughs,[1] sneezes[2] exhales,[3] or vomits,[4] but can also arise from flushing a toilet,[5] or disturbing dried contaminated feces.[6]
Treatment of some respiratory diseases utilize aerosolization of a liquid medication using a nebulizer, which is then breathed in for direct transport to the lungs.
In the context of chemical and biological weapons, aerosolization is a means of dispersing a chemical or biological agent in an attack. See for example "Botulinum Toxin as a Biological Weapon".[7]
References
- ^ Tang, J. W.; Settles, G. S. (2008). "Coughing and Aerosols". New England Journal of Medicine 359 (15): e19. doi:10.1056/NEJMicm072576. PMID 18843121. edit
- ^ "Microbe-laden aerosols" (PDF 217 KB). Microbiology Today (November 2005).
- ^ Johnson, G. R.; Morawska, L. (2009). "The Mechanism of Breath Aerosol Formation". Journal of Aerosol Medicine and Pulmonary Drug Delivery 22 (3): 229–237. doi:10.1089/jamp.2008.0720. PMID 19415984. edit
- ^ "Norovirus, Clinical Overview". Centers for Disease Control and Prevention (CDC).
- ^ Best, E. L.; Sandoe, J. A. T.; Wilcox, M. H. (2012). "Potential for aerosolization of Clostridium difficile after flushing toilets: The role of toilet lids in reducing environmental contamination risk". Journal of Hospital Infection 80 (1): 1–5. doi:10.1016/j.jhin.2011.08.010. PMID 22137761. edit
- ^ "Hantavirus Pulmonary Syndrome (HPS): What You Need To Know" (PDF 1.4 MB). CDC.
- ^ "Botulinum Toxin as a Biological Weapon". Center For Infectious Disease Research & Policy.
UpToDate Contents
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English Journal
- Comparison of two in vitro systems to assess cellular effects of nanoparticles-containing aerosols.
- Fröhlich E, Bonstingl G, Höfler A, Meindl C, Leitinger G, Pieber TR, Roblegg E.SourceCenter for Medical Research, and Department of Internal Medicine, Division of Endocrinology and Nuclear Medicine, Medical University of Graz, Graz, Austria. eleonore.froehlich@medunigraz.at
- Toxicology in vitro : an international journal published in association with BIBRA.Toxicol In Vitro.2013 Feb;27(1):409-17. doi: 10.1016/j.tiv.2012.08.008. Epub 2012 Aug 10.
- Inhalation treatment with nanoparticle containing aerosols appears a promising new therapeutic option but new formulations have to be assessed for efficacy and toxicity. We evaluated the utility of a VITROCELL®6 PT-CF+PARI LC SPRINT® Baby Nebulizer (PARI BOY) system compared with a conventional Mi
- PMID 22906573
- Pathology of Experimental Aerosol Zaire Ebolavirus Infection in Rhesus Macaques.
- Twenhafel NA, Mattix ME, Johnson JC, Robinson CG, Pratt WD, Cashman KA, Wahl-Jensen V, Terry C, Olinger GG, Hensley LE, Honko AN.SourceFort Detrick, MD, USA.
- Veterinary pathology.Vet Pathol.2013 Jan 18. [Epub ahead of print]
- There is limited knowledge of the pathogenesis of human ebolavirus infections and no reported human cases acquired by the aerosol route. There is a threat of ebolavirus as an aerosolized biological weapon, and this study evaluated the pathogenesis of aerosol infection in 18 rhesus macaques. Importan
- PMID 23262834
- Comprehensive Proteomics Approach in Characterizing and Quantifying Allergenic Proteins from Northern Shrimp: Toward Better Occupational Asthma Prevention.
- Abdel Rahman AM, Kamath SD, Gagné S, Lopata AL, Helleur R.SourceSamuel Lunenfeld Research Institute, Mount Sinai Hospital , Toronto, Ontario, Canada.
- Journal of proteome research.J Proteome Res.2013 Jan 17. [Epub ahead of print]
- Occupational asthma is a major chronic health dilemma among workers involved in the seafood industry. Several proteins notoriously known to cause asthma have been reported in different seafood. This work involves the application of an allergenomics strategy to study the most potent allergens of nort
- PMID 23268739
Japanese Journal
- Establishment and Clinical Applications of a Portable System for Capturing Influenza Viruses Released through Coughing
- Hatagishi Etsuko,Okamoto Michiko,Ohmiya Suguru,Yano Hisakazu,Hori Toru,Saito Wakana,Miki Hiroshi,Suzuki Yasushi,Saito Reiko,Yamamoto Taro,Shoji Makoto,Morisaki Yoshihisa,Sakata Soichiro,Nishimura Hidekazu
- PLoS ONE 9(8), e103560, 2014-08-01
- … The approximate viral recovery rate of this system was 10% in simulation experiments to collect and quantify the viral particles aerosolized by a nebulizer. …
- NAID 120005477032
- Efficacy of aerosolized liposomal amphotericin B against murine invasive pulmonary mucormycosis
- Mihara Tomo,Kakeya Hiroshi,Izumikawa Koichi,Obata Yoko,Nishino Tomoya,Takazono Takahiro,Kosai Kosuke,Morinaga Yoshitomo,Kurihara Shintaro,Nakamura Shigeki,Imamura Yoshifumi,Miyazaki Taiga,Tsukamoto Misuzu,Yamamoto Yoshihiro,Yanagihara Katsunori,Tashiro Takayoshi,Kohno Shigeru
- Journal of Infection and Chemotherapy 20(2), 104-108, 2014-02
- … We evaluated the efficacy of inhaled aerosolized L-AMB in murine invasive pulmonary mucormycosis. … Infected mice were assigned to one of the following 3 treatment groups: (i) control, (ii) treatment only (aerosolized L-AMB from day 1-5 after challenge), and (iii) prophylaxis followed by treatment (aerosolized L-AMB from day -2 to 5 before and after challenge). …
- NAID 120005477014
- Rapamycin Attenuates Pulmonary Allergic Vasculitis in Murine Model by Reducing TGF-β Production in the Lung
- Koizumi Rumi,Sasaki Nobuhito,Nakamura Yutaka,Suzuki Naomi,Sawai Takashi,Yamauchi Kohei
- Allergology International 63(3), 457-466, 2014
- … The positive controls were exposed to aerosolized OVA daily for 7 days. … The other group of mice was administered with rapamycin (1mg/kg) intraperitoneally, in parallel with daily exposure to aerosolized OVA for 7 days. …
- NAID 130004687704
Related Links
- Adj. 1. aerosolized - in the form of ultramicroscopic solid or liquid particles dispersed or suspended in air or gas. aerosolised · gaseous - existing as or having characteristics of a gas; "steam is water is the gaseous state" ...
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