WordNet
- of or derived from the cortex of the adrenal glands
- a benign epithelial tumor of glandular origin
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/05/24 10:14:41」(JST)
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Adrenocortical adenoma |
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Classification and external resources |
ICD-O |
8370/0 |
eMedicine |
radio/13 |
MeSH |
D018246 |
[edit on Wikidata]
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A adrenocortical adenoma (or adrenal cortical adenoma) is a benign tumor of the adrenal cortex.
It can present with Cushing's syndrome or primary aldosteronism.[1]
Is a well circumscribed, yellow tumour in the adrenal cortex, which is usually 2–5 cm in diameter. The color of the tumour, as with adrenal cortex as a whole, is due to the stored lipid (mainly cholesterol), from which the cortical hormones are synthesized. These tumors are frequent incidental findings at post mortem examination, and appear to have produced no significant metabolic disorder; only a very small percentage lead to Cushing's syndrome. Nevertheless, these apparently non-functioning adenomas are most often encountered in elder obese people. There is some debate that they may really represent nodules in diffuse nodular cortical hyperplasia. Very occasionally, a true adrenal cortical adenoma is associated with the clinical manifestations of Conn's syndrome, and can be shown to be excreting mineralocorticoids.
Additional images
See also
References
- ^ "Definition: adrenocortical adenoma from Online Medical Dictionary".
Glandular and epithelial neoplasms (ICD-O 8010-8589)
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Epithelium |
Papilloma/carcinoma
(8010-8139) |
- Small cell carcinoma
- Combined small cell carcinoma
- Verrucous carcinoma
- Squamous cell carcinoma
- Basal cell carcinoma
- Transitional cell carcinoma
- Inverted papilloma
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Glands |
Adenomas/
adenocarcinomas
(8140-8429) |
Gastrointestinal |
- tract: Linitis plastica
- Familial adenomatous polyposis
- pancreas
- Insulinoma
- Glucagonoma
- Gastrinoma
- VIPoma
- Somatostatinoma
- Cholangiocarcinoma
- Klatskin tumor
- Hepatocellular adenoma/Hepatocellular carcinoma
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Urogenital |
- Renal cell carcinoma
- Endometrioid tumor
- Renal oncocytoma
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Endocrine |
- Prolactinoma
- Multiple endocrine neoplasia
- Adrenocortical adenoma/Adrenocortical carcinoma
- Hurthle cell
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Other/multiple |
- Neuroendocrine tumor
- Adenoid cystic carcinoma
- Oncocytoma
- Clear cell adenocarcinoma
- Apudoma
- Cylindroma
- Papillary hidradenoma
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Adnexal and
skin appendage (8390-8429) |
- sweat gland
- Syringocystadenoma papilliferum
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Cystic, mucinous,
and serous (8440-8499) |
Cystic general |
- Cystadenoma/Cystadenocarcinoma
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Mucinous |
- Signet ring cell carcinoma
- Mucinous cystadenoma / Mucinous cystadenocarcinoma
- Mucoepidermoid carcinoma
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Serous |
- Ovarian serous cystadenoma / Pancreatic serous cystadenoma / Serous cystadenocarcinoma / Papillary serous cystadenocarcinoma
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Ductal, lobular,
and medullary (8500-8549) |
Ductal carcinoma |
- Mammary ductal carcinoma
- Pancreatic ductal carcinoma
- Comedocarcinoma
- Paget's disease of the breast / Extramammary Paget's disease
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Lobular carcinoma |
- Lobular carcinoma in situ
- Invasive lobular carcinoma
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Medullary carcinoma |
- Medullary carcinoma of the breast
- Medullary thyroid cancer
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Acinar cell (8550-8559) |
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Other |
Complex epithelial (8560-8589) |
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- See also
- Template:Epithelium and epithelial tissue
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Tumors: endocrine gland neoplasia (C73–C75/D34–D35, 193–194/226–227)
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Pancreas |
- Pancreatic cancer
- Pancreatic neuroendocrine tumor
- α: Glucagonoma
- β: Insulinoma
- δ: Somatostatinoma
- G: Gastrinoma
- VIPoma
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Pituitary |
- Pituitary adenoma: Prolactinoma
- ACTH-secreting pituitary adenoma
- GH-secreting pituitary adenoma
- Craniopharyngioma
- Pituicytoma
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Thyroid |
- Thyroid cancer (malignant): epithelial-cell carcinoma
- Papillary
- Follicular/Hurthle cell
- Parafollicular cell
- Anaplastic
- Lymphoma
- Squamous-cell carcinoma
- Benign
- Thyroid adenoma
- Struma ovarii
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Adrenal tumor |
- Cortex
- Adrenocortical adenoma
- Adrenocortical carcinoma
- Medulla
- Pheochromocytoma
- Neuroblastoma
- Paraganglioma
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Parathyroid |
- Parathyroid neoplasm
- Adenoma
- Carcinoma
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Pineal gland |
- Pinealoma
- Pinealoblastoma
- Pineocytoma
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MEN |
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UpToDate Contents
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English Journal
- Estrogen-related receptor α in normal adrenal cortex and adrenocortical tumors: Involvement in development and oncogenesis.
- Felizola SJ, Nakamura Y, Hui XG, Satoh F, Morimoto R, M McNamara K, Midorikawa S, Suzuki S, Rainey WE, Sasano H.SourceTohoku University Graduate School of Medicine, Department of Pathology, Sendai, Japan.
- Molecular and cellular endocrinology.Mol Cell Endocrinol.2013 Jan 30;365(2):207-11. doi: 10.1016/j.mce.2012.10.020. Epub 2012 Oct 30.
- AIMS: The nuclear hormone receptor estrogen-related receptor α (ERRα) regulates the activation of mitochondrial genes in various human tissues, but its role in the adrenal gland and its disorders has not been defined. Therefore, we examined ERRα expression in both normal adrenal cortex (NAC) and
- PMID 23123734
- Identification of a CpG island methylator phenotype in adrenocortical carcinomas.
- Barreau O, Assié G, Wilmot-Roussel H, Ragazzon B, Baudry C, Perlemoine K, René-Corail F, Bertagna X, Dousset B, Hamzaoui N, Tissier F, de Reynies A, Bertherat J.SourceAssistance Publique Hôpitaux de Paris, Hôpital Cochin, 75014 Paris, France. jerome.bertherat@inserm.fr.
- The Journal of clinical endocrinology and metabolism.J Clin Endocrinol Metab.2013 Jan;98(1):E174-84. doi: 10.1210/jc.2012-2993. Epub 2012 Oct 23.
- Purpose: DNA methylation is a mechanism for gene expression silencing in cancer. Limited information is available for adrenocortical tumors. Abnormal methylation at the IGF2/H19 locus is common in adrenocortical carcinomas. Our aim was to characterize the methylation in adrenocortical carcinomas at
- PMID 23093492
Japanese Journal
- A case of Cushing's syndrome due to bilateral cortisol-secreting adenomas with unilateral DHEAS oversecretion
- , , ,
- Endocrine Journal 62(3), 283-288, 2015
- … Pathological examination of the resected glands showed bilateral adrenocortical adenomas, one on the left with a diameter of 3 cm, and two on the right with diameters of 0.7 cm and 1.3 cm. … Ours is the first case of a patient with bilateral cortisol-secreting adenomas with unilateral oversecretion of dehydroepiandrosterone sulphate. …
- NAID 130005060857
- A case of Cushing's syndrome due to bilateral cortisol-secreting adenomas with unilateral DHEAS oversecretion
- , , ,
- Endocrine Journal advpub(0), 2015
- … Pathological examination of the resected glands showed bilateral adrenocortical adenomas, one on the left with a diameter of 3 cm, and two on the right with diameters of 0.7 cm and 1.3 cm. … Ours is the first case of a patient with bilateral cortisol-secreting adenomas with unilateral oversecretion of dehydroepiandrosterone sulphate. …
- NAID 130004770493
Related Links
- Most adrenocortical adenomas are non-secreting (approximately 80%). Secreting adenomas are 4-5 times more common in women than in men and the average age of onset is about 40. They can cause oversecretion syndromes ...
- A adrenocortical adenoma (or adrenal cortical adenoma) is a benign tumor of the adrenal cortex. It can present with Cushing's syndrome or primary aldosteronism. [1] Is a well circumscribed, yellow tumour in the adrenal cortex, which ...
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- 関
- adrenal cortex、adrenal cortical、adrenal cortices