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1. 不整脈原性右室心筋症：発症機序と遺伝arrhythmogenic right ventricular cardiomyopathy pathogenesis and genetics [show details]
…gene contains the response element for PPAR gamma, an adipogenic transcription factor. If the TMEM43 gene mutation causes dysregulation of an adipogenic pathway regulated by PPAR gamma, this dysregulation…
2. ユーイング肉腫ファミリーの腫瘍の疫学、病理、および分子遺伝学epidemiology pathology and molecular genetics of the ewing sarcoma family of tumors [show details]
…cells (MSC). MSCs isolated from bone marrow can differentiate into osteogenic, chondrogenic, or adipogenic lineages. Expression of the ES-specific oncoprotein EWS-FLI blocks MSC differentiation , while…
3. 思春期の重度肥満への外科的マネージメントsurgical management of severe obesity in adolescents [show details]
…bone mass in adults and is probably caused by a combination of reduced mechanical load, changes in adipogenic hormones, and nutritional deficiencies. In adolescents, reduced bone mass has been noted two years…

English Journal

Characterization of human adipose tissue-derived stem cells in vitro culture and in vivo differentiation in a temperature-sensitive chitosan/β- glycerophosphate/collagen hybrid hydrogel.

Song K1, Li L2, Yan X2, Zhang W2, Zhang Y2, Wang Y3, Liu T4.
Materials science & engineering. C, Materials for biological applications.Mater Sci Eng C Mater Biol Appl.2017 Jan 1;70(Pt 1):231-240. doi: 10.1016/j.msec.2016.08.085. Epub 2016 Aug 31.
In this study, the interaction of human adipose tissue-derived stem cells (ADSCs) with chitosan/β-glycerophosphate/collagen (C/GP/Co) hybrid hydrogel was test, followed by investigating the capability of engineered adipose tissue formation using this ADSCs seeded hydrogel. The ADSCs were harvested
PMID 27770886

Identification of suitable reference genes for quantitative gene expression analysis in rat adipose stromal cells induced to trilineage differentiation.

Santos BP1, da Costa Diesel LF2, da Silva Meirelles L3, Nardi NB4, Camassola M5.
Gene.Gene.2016 Dec 15;594(2):211-219. doi: 10.1016/j.gene.2016.09.002. Epub 2016 Sep 4.
This study was designed to (i) identify stable reference genes for the analysis of gene expression during in vitro differentiation of rat adipose stromal cells (rASCs), (ii) recommend stable genes for individual treatment conditions, and (iii) validate these genes by comparison with normalization re
PMID 27601259

Liu X1, Liu R1, Cao B1, Ye K1, Li S1, Gu Y1, Pan Z1, Ding J2.
Biomaterials.Biomaterials.2016 Dec;111:27-39. doi: 10.1016/j.biomaterials.2016.09.023. Epub 2016 Sep 30.
While various material factors have been shown to influence cell behaviors, recent studies started to pay attention to the effects of some material cues on "subcellular" geometry of cells, such as self-deformation of cell nuclei. It is particularly interesting to examine whether a self deformation h
PMID 27716524