Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/10/28 21:06:40」(JST)

English Journal

The DNA damage response kinases DNA-dependent protein kinase (DNA-PK) and ataxia telangiectasia mutated (ATM) Are stimulated by bulky adduct-containing DNA.

Kemp MG1, Lindsey-Boltz LA, Sancar A.
The Journal of biological chemistry.J Biol Chem.2011 Jun 3;286(22):19237-46. doi: 10.1074/jbc.M111.235036. Epub 2011 Apr 12.
A variety of environmental, carcinogenic, and chemotherapeutic agents form bulky lesions on DNA that activate DNA damage checkpoint signaling pathways in human cells. To identify the mechanisms by which bulky DNA adducts induce damage signaling, we developed an in vitro assay using mammalian cell nu
PMID 21487018

Comparison of clastogen-induced gene expression profiles in wild-type and DNA repair-deficient Rad54/Rad54B cells.

Mahabir AG1, Schaap MM, Pennings JL, van Benthem J, Hendriksen CF, van Steeg H.
BMC genomics.BMC Genomics.2010 Jan 12;11:24. doi: 10.1186/1471-2164-11-24.
BACKGROUND: Previously we found that Rad54/Rad54B cells are more sensitive towards mitomycin C (MMC) as compared to wild-type (WT) cells. This difference in sensitivity was absent upon exposure to other clastogens like bleomycin (BLM) and gamma-radiation. In order to get further insight into possibl
PMID 20067618

GenoMass--a computer software for automated identification of oligonucleotide DNA adducts from LC-MS analysis of DNA digests.

Liao Q1, Shen C, Vouros P.
Journal of mass spectrometry : JMS.J Mass Spectrom.2009 Apr;44(4):549-60. doi: 10.1002/jms.1532.
In the investigation of oligonucleotides, DNA and their adducts by LC-MS, a myriad of data are generated that make manual data processing quite difficult. This paper describes a 'reversed pseudo-combinatorial' approach for fragment identification and the software implementation of this approach. Com
PMID 19053159

リンク元	「アセトキシアセチルアミノフルオレン」

Acetoxyacetylaminofluorene
	IUPAC name [Acetyl(9H-fluoren-2-yl)amino] acetate
	Other names N-Acetoxy-2-acetamidofluorene; N-Acetoxy-2-acetylaminofluorene; Acetoxy AAF; Acetoxyacetamidofluorene; Acetoxyfluorenylacetamide;
Identifiers
Abbreviations	NAAAF
CAS number	6098-44-8
PubChem	22469
ChemSpider	21074
MeSH	Acetoxyacetylaminofluorene
ChEBI	CHEBI:234426
ChEMBL	CHEMBL85327
Jmol-3D images	Image 1; Image 2
	SMILES CC(=O)ON(C(C)=O)c1ccc-2c(Cc3ccccc-23)c1 CC(=O)ON(C(C)=O)C1=CC=C2C(CC3=C2C=CC=C3)=C1 ;
	InChI InChI=1S/C17H15NO3/c1-11(19)18(21-12(2)20)15-7-8-17-14(10-15)9-13-5-3-4-6-16(13)17/h3-8,10H,9H2,1-2H3 ; Key: NFOMHWALMFWNAQ-UHFFFAOYSA-N InChI=1/C17H15NO3/c1-11(19)18(21-12(2)20)15-7-8-17-14(10-15)9-13-5-3-4-6-16(13)17/h3-8,10H,9H2,1-2H3; Key: NFOMHWALMFWNAQ-UHFFFAOYAD ;
Properties
Molecular formula	C17H15NO3
Molar mass	281.31 g mol−1
log P	3.327
	Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
	(verify) (what is: /?)
	Infobox references