同: ANC

WordNet

name or recite the numbers in ascending order; "The toddler could count to 100"
the total number counted; "a blood count"
the act of counting; reciting numbers in ascending order; "the counting continued for several hours" (同)counting, numeration, enumeration, reckoning, tally
a nobleman (in various countries) having rank equal to a British earl
have faith or confidence in; "you can count on me to help you any time"; "Look to your friends for support"; "You can bet on that!"; "Depend on your family in times of crisis" (同)bet, depend, look, calculate, reckon
have weight; have import, carry weight; "It does not matter much" (同)matter, weigh
put into a group; "The academy counts several Nobel Prize winners among its members" (同)number
determine the number or amount of; "Can you count the books on your shelf?"; "Count your change" (同)number, enumerate, numerate
have a certain value or carry a certain weight; "each answer counts as three points"
include as if by counting; "I can count my colleagues in the opposition"
something that is conceived or that exists independently and not in relation to other things; something that does not depend on anything else and is beyond human control; something that is not relative; "no mortal being can influence the absolute"
perfect or complete or pure; "absolute loyalty"; "absolute silence"; "absolute truth"; "absolute alcohol"
complete and without restriction or qualification; sometimes used informally as intensifiers; "absolute freedom"; "an absolute dimwit"; "a downright lie"; "out-and-out mayhem"; "an out-and-out lie"; "a rank outsider"; "many right-down vices"; "got the job through sheer persistence"; "sheer stupidity" (同)downright, out-and-out, rank, right-down, sheer
not capable of being violated or infringed; "infrangible human rights" (同)infrangible, inviolable
expressing finality with no implication of possible change; "an absolute guarantee to respect the nations authority"
not limited by law; "an absolute monarch"
the chief phagocytic leukocyte; stains with either basic or acid dyes (同)neutrophile

PrepTutorEJDIC

(一つ一つ順に)〈数〉'を'『数える』,〈物〉'を'数え上げる《+『up』+『名,』+『名』+『up』》 / …'を'『勘定に入れる』,含める(include) / …'を'『思う』,みなす(consider) / 数を数える,計算する《+『up』》 / 数にはいる,数に含まれる / 価値がある,重大である / 〈C〉〈U〉『数えること』,『計算』 / 〈U〉総数,総計 / 〈U〉(起訴状の)訴因 / 《the~》(ボクシングで)カウント(選手がノックダウンされたときレフリーが1から10まで数えること) / 〈C〉(野救で打者の)ボールカウント / 〈U〉《話》考慮,注目(account)
(英国以外の)伯爵
『まったくの』,完全な(complete) / 『絶対的な力を持った』,絶対の / 確かな,確固とした(certain) / 無条件の,制約のない / (文法で)独立の,単独の

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/09/28 12:27:21」(JST)

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Absolute neutrophil count (ANC) is a measure of the number of neutrophil granulocytes^[1] (also known as polymorphonuclear cells, PMN's, polys, granulocytes, segmented neutrophils or segs) present in the blood. Neutrophils are a type of white blood cell that fights against infection.

The ANC is almost always part of a larger blood panel called the complete blood count. The ANC is calculated from measurements of the total number of white blood cells (WBC), usually based on the combined percentage of mature neutrophils (sometimes called "segs," or segmented cells) and bands, which are immature neutrophils.

Clinical significance

The reference range for ANC in adults varies by study, but 1500 to 8000 cells per microliter is typical. An ANC less than 500 cells/µL is defined as neutropenia and significantly increases risk of infection. Neutropenia is the condition of a low ANC, and the most common condition where an ANC would be measured is in the setting of chemotherapy for cancer.

Neutrophilia indicates an elevated count. This is also known as a "left shift" and can be indicative of:

Premature release of myeloid cells from the bone marrow.
A leukemoid reaction.

Calculation

ANC = $(\%neutrophils + \%bands)\times (WBC)\over (100)$

or

ANC = (Absolute-Polys + Absolute-Bands)

In the above, we assume that the WBC is given in cells/µL (or thousand cells/mL, i.e. K/mL) such as 8,800 cells/µL or 8,800 K/mL; if the WBC were given in K/µL (instead of cells/µL or K/mL), such as 8.8 K/µL, you would first convert to cells/µL by multiplying the WBC by 1000.

The unit of ANC is cells per microliter of blood (abbreviated cells/µL; a microliter is equal to one cubic millimeter because 1,000,000 cubic millimeters are equal to one liter).

Ranges

NCI Risk Category	ANC
0	Within normal limits
1	≥1500 - <2000/mm³
2	≥1000 - <1500/mm³
3	≥500 - <1000/mm³
4	< 500/mm³

Source: NCI CTC Toxicity scale Version 2.0 [1]

Related tests

In some cases, a ratio is reported in addition to the sum. This is known as the "I/T ratio".^[2]^[3]

References

^ Al-Gwaiz LA, Babay HH (2007). "The diagnostic value of absolute neutrophil count, band count and morphologic changes of neutrophils in predicting bacterial infections". Med Princ Pract 16 (5): 344–7. doi:10.1159/000104806. PMID 17709921.
^ Walliullah SM, Islam MN, Siddika M, Hossain MA, Chowdhury AK (January 2009). "Role of Micro-ESR and I/T Ratio in the Early Diagnosis of Neonatal Sepsis". Mymensingh Med J 18 (1): 56–61. PMID 19182751.
^ Russell GA, Smyth A, Cooke RW (July 1992). "Receiver operating characteristic curves for comparison of serial neutrophil band forms and C reactive protein in neonates at risk of infection". Arch. Dis. Child. 67 (7 Spec No): 808–12. doi:10.1136/adc.67.7_Spec_No.808. PMC 1590438. PMID 1519980.

UpToDate Contents

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English Journal

Pretreatment neutrophil/lymphocyte ratio is superior to platelet/lymphocyte ratio as a predictor of long-term mortality in breast cancer patients.

Azab B, Shah N, Radbel J, Tan P, Bhatt V, Vonfrolio S, Habeshy A, Picon A, Bloom S.SourceDepartment of Surgery, Staten Island University Hospital, 475 Seaview Avenue, Staten Island, NY, 10305, USA, basemazab5@gmail.com.
Medical oncology (Northwood, London, England).Med Oncol.2013 Mar;30(1):432. doi: 10.1007/s12032-012-0432-4. Epub 2013 Jan 3.
The aim of our study was to assess the predictive value of platelet/lymphocyte ratio (PLR) and neutrophil/lymphocyte ratio (NLR) in terms of survival in breast cancer patients. This is an observational study of 437 breast cancer patients treated between January 2004 and December 2006. Survival statu
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Ifosfamide, carboplatin, and etoposide for neuroblastoma: A high-dose salvage regimen and review of the literature.

Kushner BH, Modak S, Kramer K, Basu EM, Roberts SS, Cheung NK.SourceDepartment of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York.. kushnerb@mskcc.org.
Cancer.Cancer.2013 Feb 1;119(3):665-71. doi: 10.1002/cncr.27783. Epub 2012 Sep 5.
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Japanese Journal

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医療薬学 34(1), 73-78, 2008-01-10
… Considered together with the change in absolute neutrophil count observed, these findings suggested that the doses of CPT-11, 5-FU and L-leucovorin be adjusted to 26mg/m^2, 324mg/m^2 and 195mg/m^2 respectively and the washout period be extended. …
NAID 110006546903

当科〔昭和大学医学部血液内科〕における成人造血器腫瘍に対する非血縁者間臍帯血移植の成績

前田崇,柳沢孝次,碓井隆子,中嶋秀人詞,服部憲路,下間順子,安達大輔,斉藤文護,久武純一,川上恵一郎,中牧剛,友安茂,塩沢英輔,瀧本雅文,太田秀一
昭和医学会雑誌 65(5), 394-400, 2005
… The median time to >500/μl absolute neutrophil count was 22.6 days, and 8 patients developed grade III to IV acute GVHD. …
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