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- ウレアプラズマ・ウレアリチカム
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- Ureaplasma urealyticum、U. urealyticum
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Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/08/10 08:15:24」(JST)
[Wiki en表示]
| Ureaplasma urealyticum |
| Scientific classification |
| Kingdom: |
Bacteria |
| Division: |
Firmicutes |
| Class: |
Mollicutes |
| Order: |
Mycoplasmatales |
| Family: |
Mycoplasmataceae |
| Genus: |
Ureaplasma |
| Species: |
U. urealyticum |
| Binomial name |
Ureaplasma urealyticum
Shepard et al., 1974 |
Ureaplasma urealyticum is a bacterium belonging to the family Mycoplasmataceae. Its type strain is T960.
Contents
- 1 Clinical significance
- 2 Classification
- 3 Treatment
- 4 References
- 5 External links
Clinical significance[edit source | edit]
U. urealyticum is part of the normal genital flora of both men and women.[1] It is found in about 70% of sexually active humans.[2]
It had also been associated with a number of diseases in humans, including non-specific urethritis (NSU), infertility, chorioamnionitis, stillbirth, premature birth, and, in the perinatal period, pneumonia, bronchopulmonary dysplasia[3] and meningitis.
However, given the relatively low pathogenicity of the organism its role in some of these diseases remains contentious.
U. urealyticum has been noted as one of the infectious causes of sterile pyuria.[4]
Classification[edit source | edit]
There are six recognised Ureaplasma species, They have a GC content of 27–30%, and a genome size ranging between 0.76–1.17 Mbp, and cholesterol is required for growth. [5] A defining characteristic of the genus is that they perform urea hydrolysis.
It is now recommended that some strains originally classified as Ureaplasma urealyticum should be treated as a new species, U. parvum.
Treatment[edit source | edit]
Doxycycline is the drug of choice but Azithromycin is also used as a 5 day course rather than a single dose that would be used to treat Chlamydia;[6] streptomycin is an alternative but is less popular because it must be injected. Penicillins are ineffective — U. urealyticum does not have a cell wall,[7] which is the drug's main target.[8]
References[edit source | edit]
- ^ "Ureaplasma urealyticum- Clinical significance". Meducation.net.
- ^ "Ureaplasma urealyticum". HealthExpress.
- ^ Kafetzis DA, Skevaki CL, Skouteri V, et al (October 2004). "Maternal genital colonization with Ureaplasma urealyticum promotes preterm delivery: association of the respiratory colonization of premature infants with chronic lung disease and increased mortality". Clin. Infect. Dis. 39 (8): 1113–22. doi:10.1086/424505. PMID 15486833.
- ^ Dieter RS (2000). "Sterile pyuria: a differential diagnosis". Compr Ther 26 (3): 150–2. doi:10.1007/s12019-000-0001-1. PMID 10984817.
- ^ "Ureaplasma urealyticum- Classification". Meducation.net.
- ^ http://www.thesticlinic.com/ureaplasma-urealyticum.aspx
- ^ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128564/
- ^ http://www.elmhurst.edu/~chm/vchembook/652penicillin.html
External links[edit source | edit]
- Long Term Effects of Ureaplasma
- Ureaplasma Infection at eMedicine
- Ureaplasma Genome Projects from Genomes OnLine Database
UpToDate Contents
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English Journal
- The correlation of the lifestyle and medical conditions with the vaginal infections and production of 2-phenylethanol.
- Findri-Guštek S, Petek MJ, Sarajlija H, Mršić G, Džepina AM, Oreščanin V.SourceFindri-Guštek Ltd, Ninska 5A, Sesvete, Zagreb, Croatia.
- Archives of gynecology and obstetrics.Arch Gynecol Obstet.2012 Sep;286(3):671-82. Epub 2012 May 9.
- OBJECTIVE: The objective of this study was determination of causative factors of the genital infections and their correlation with various predictor variables. Secondary objectives included: (1) determination of the presence and the type of low molecular weight metabolites in the samples of vaginal
- PMID 22569709
- Evidence for the predominance of a single tet(M) gene sequence type in tetracycline-resistant Ureaplasma parvum and Mycoplasma hominis isolates from Tunisian patients.
- Mardassi BB, Aissani N, Moalla I, Dhahri D, Dridi A, Mlik B.SourceUnit of Mycoplasmas, Laboratory of Molecular Microbiology, Vaccinology, and Biotechnology Development, Institut Pasteur de Tunis, 13 Place Pasteur, B.P. 74, 1002 Tunis-Belvédère, Tunis, Tunisia.
- Journal of medical microbiology.J Med Microbiol.2012 Sep;61(Pt 9):1254-61. Epub 2012 May 11.
- Resistance to tetracyclines in genital mycoplasmas is due mainly to acquisition of the tet(M) determinant, which is frequently associated with conjugative transposon elements of the Tn916/Tn1545 family. The aim of the present work was to evaluate the prevalence of tet(M) in Tunisian isolates and to
- PMID 22580915
Japanese Journal
- Frequency of Chlamydia trachomatis in Ureaplasma-positive healthy women attending their first prenatal visit in a community hospital in Sapporo, Japan
- Yamazaki Tomohiro,Matsumoto Megumi,Matsuo Junji,Abe Kiyotaka,Minami Kunihiro,Yamaguchi Hiroyuki
- BMC Infectious Diseases 12(1), 82, 2012-04-02
- … [Background]Although Chlamydia trachomatis is the most commonly reported pathogen that causes urogenital infection such as urethritis or cervicitis, Ureaplasma parvum and Ureaplasma urealyticum, which are commensals in the genital tract, have also now been recognized as contributors to urogenital infection. … urealyticum is related to that of C. …
- NAID 120003945386
- 非クラミジア性非淋菌性子宮頸管炎58例の検討 : Ureaplasma urealyticum、 Mycoplasma hominis のひろがり
- 酒井 英二
- 日本性感染症学会誌 = Japanese archives of sexually transmitted diseases 20(1), 154-161, 2009-07-10
- NAID 10027048615
Related Links
- Ureaplasma urealyticum (formerly T-mycoplasma) is a genital mycoplasma which colonize the human genital tract and produce infection. The organism is sometimes referred to as “T-strain” of mycoplasma because it produces tiny ...
- Ureaplasma urealyticum can be grown on artificial culture media. The organism requires complex enriched culture media for growth, because it has limited biosynthetic abilities. Ureaplasma urealyticum grows particularly well on ...
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