WordNet

stain by smearing or daubing with a dirty substance
a thin tissue or blood sample spread on a glass slide and stained for cytologic examination and diagnosis under a microscope (同)cytologic smear, cytosmear
slanderous defamation (同)vilification, malignment
make a smudge on; soil by smudging (同)blur, smudge, smutch

PrepTutorEJDIC

(油性・粘着性のものを)…に塗る…(…で)…‘を'汚す《+『名』+『with』+『名』〈油など〉》 / (…に)〈油など〉‘を'塗りつける《+『名』〈油など〉+『on』(『over』)+『名』》 / …‘を'こすって不明瞭にする,消す / 〈人の名誉など〉‘を'傷つける,中傷する / 汚れる / かすれる,分鮮明になる / (油などの)汚れ,しみ / 中傷 / (顕微鏡で見るためスライドに塗った)塗布[標本]

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/04/16 23:58:57」(JST)

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A positive Tzanck test, showing three multinucleated giant cells ("Tzanck cells") in center.

In dermatopathology, the Tzanck test, also Tzanck smear, is scraping of an ulcer base to look for Tzanck cells. It is sometimes also called the Chickenpox skin test and the herpes skin test.

Tzanck cells (multinucleated giant cells) are found in:

Herpes simplex^[1]
Varicella and herpes zoster
Pemphigus vulgaris
Cytomegalovirus

Procedure

Unroof vesicle and scrape base w/ sterile surgical blade
Smear onto clean glass slide
Fix w/ gentle heat or air dry
Fix w/ MeOH
Stain w/ Giemsa, methylene blue or Wright’s stain
Microscopic examination using oil immersion lens. (Look for multinucleate giant cells)^[2]

Eponym

It is named after Arnault Tzanck (1886–1954), a French dermatologist.

References

^ Folkers E, Oranje AP, Duivenvoorden JN, van der Veen JP, Rijlaarsdam JU, Emsbroek JA (August 1988). "Tzanck smear in diagnosing genital herpes". Genitourinary medicine 64 (4): 249–54. PMC 1194227. PMID 3169755.
^ Pettit, Normal Microbiota of the Skin, ATSU School of Osteopathic Medicine Arizona, Lecture Slides. Jan 2013.

External links

Tzanck test - medlineplus.org.
Definition of Tzanck test - medterms.com.

This article related to pathology is a stub. You can help Wikipedia by expanding it.

UpToDate Contents

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1. 皮膚の手技 dermatologic procedures
2. 性器単純ヘルペスウイルス感染の疫学、臨床症状、および診断 epidemiology clinical manifestations and diagnosis of genital herpes simplex virus infection
3. 皮膚の水疱を有する患者に対するアプローチ approach to the patient with cutaneous blisters
4. 単純ヘルペスウイルス1型感染の臨床症状および診断 clinical manifestations and diagnosis of herpes simplex virus type 1 infection
5. 性器潰瘍患者へのアプローチ approach to the patient with genital ulcers

English Journal

Majocchi's granuloma: a symptom complex caused by fungal pathogens.

Ilkit M, Durdu M, Karakaş M.SourceDivision of Mycology, Department of Microbiology, Baş kent University Adana Hospital, Adana, Turkey. milkit@cu.edu.tr
Medical mycology : official publication of the International Society for Human and Animal Mycology.Med Mycol.2012 Jul;50(5):449-57. doi: 10.3109/13693786.2012.669503. Epub 2012 Mar 21.
Majocchi's granuloma (MG) is a well-recognized but uncommon infection of dermal and subcutaneous tissues that is caused by mold fungi. Although primarily caused by keratinophilic dermatophytes such as anthropophilic Trichophyton rubrum, species from the Aspergillus and Phoma genera have been occasio
PMID 22435879