Peroxisomes of organisms belonging to the protist group Kinetoplastea, which include trypanosomatid parasites of the genera Trypanosoma and Leishmania, are unique in playing a crucial role in glycolysis and other parts of intermediary metabolism. They sequester the majority of the glycolytic enzymes
Leucine-684: A conserved residue of an AMP-acetyl CoA synthetase (AceCS) from Leishmania donovani is involved in substrate recognition, catalysis and acetylation.
Gene.Gene.2016 Apr 15;580(2):125-33. doi: 10.1016/j.gene.2016.01.011. Epub 2016 Jan 12.
AMP-acetyl CoA synthetase (AMP-AceCS) is a key enzyme which catalyzes the activation of acetate to acetyl CoA, an important intermediate at the cross roads of various anabolic and catabolic pathways. Multiple sequence alignment of Leishmania donovani AceCS with other organisms revealed the presence
Epidemiology and infection.Epidemiol Infect.2016 Apr;144(5):1010-3. doi: 10.1017/S0950268814002234. Epub 2014 Aug 29.
Chagas disease is an important emerging disease in Texas that results in cardiomyopathy in about 30% of those infected with the parasite Trypanosoma cruzi. Between the years 2008 and 2012, about 1/6500 blood donors were T. cruzi antibody-confirmed positive. We found older persons and minority popula
Trypanosomatina information including symptoms, causes, diseases, symptoms, treatments, and other medical and health issues. ... Introduction: Trypanosomatina Description of Trypanosomatina Trypanosomatina: suborder of ...