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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/05/29 22:51:29」(JST)

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Pseudallescheria boydii is a species of fungus classified under Ascomycota.^[1] It is associated with some forms of eumycetoma^[2] and maduromycosis.^[3] The asexual form of this organism is named Scedosporium apiospermum.^[4]

This fungus killed three athletes injured in the 1997 Maccabiah Games when at the opening ceremony a bridge collapsed into the Yarkon River.

Treatment of infections with P. boydii is complicated by resistance to many standard antifungal agents that are usually used for filamentous fungi.^[5]

References [edit]

^ Pseudallescheria at the US National Library of Medicine Medical Subject Headings (MeSH)
^ "Filamentous Fungi".
^ Janda-Ulfig K, Ulfig K, Cano J, Guarro J (June 2008). "A study of the growth of Pseudallescheria boydii isolates from sewage sludge and clinical sources on tributyrin, rapeseed oil, biodiesel oil and diesel oil". Ann Agric Environ Med 15 (1): 45–9. PMID 18581978.
^ Guarro J, Kantarcioglu AS, Horré R, et al. (June 2006). "Scedosporium apiospermum: changing clinical spectrum of a therapy-refractory opportunist". Med. Mycol. 44 (4): 295–327. doi:10.1080/13693780600752507. PMID 16772225.
^ Wiederhold, N. P.; Lewis, R. E.; Wiederhold, N. P.; Lewis, R. E. (2009). "Antifungal activity againstScedosporiumspecies and novel assays to assess antifungal pharmacodynamics against filamentous fungi". Medical Mycology 47 (4): 422–432. doi:10.1080/13693780802510224. PMID 19058049. edit

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UpToDate Contents

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1. Treatment of Scedosporium infection
2. Epidemiology, clinical manifestations, and diagnosis of Scedosporium infection
3. 真菌性副鼻腔炎 fungal rhinosinusitis
4. アゾールの薬理学 pharmacology of azoles
5. 免疫不全患者における肺感染症 pulmonary infections in immunocompromised patients

English Journal

Scedosporium apiospermum: An unreported cause of fungal sporotrichoid-like lymphocutaneous infection in Australia and review of the literature.

Boyce Z1, Collins N.
The Australasian journal of dermatology.Australas J Dermatol.2015 May;56(2):e39-42. doi: 10.1111/ajd.12119. Epub 2013 Nov 25.
Scedosporium apiospermum is a fungus emerging as a rare but important cause of both localised and disseminated infections in immunocompromised patients. Most cutaneous lesions present as mycetoma, however a review of the literature revealed an increasing number of cases worldwide presenting with lym
PMID 24266687

Antifungal activity of compounds targeting the Hsp90-calcineurin pathway against various mould species.

Lamoth F1, Alexander BD2, Juvvadi PR3, Steinbach WJ4.
The Journal of antimicrobial chemotherapy.J Antimicrob Chemother.2015 May;70(5):1408-11. doi: 10.1093/jac/dku549. Epub 2015 Jan 3.
OBJECTIVES: Invasive mould infections are associated with a high mortality rate and the emergence of MDR moulds is of particular concern. Calcineurin and its chaperone, the heat shock protein 90 (Hsp90), represent an important pathway for fungal virulence that can be targeted at different levels. We
PMID 25558076

Japanese Journal

Scedosporium apiospermumによる肺感染症の1手術例

徳永義昌,奥田昌也,池田敏裕,伊藤公一,加藤歩,横見瀬裕保
日本呼吸器外科学会雑誌 29(1), 42-45, 2015
… ，部分切除での診断は困難であったため，右肺上葉切除術を施行した．悪性所見は認めず，細菌培養ではScedosporium apiospermumを検出し，スケドスポリウムによる肺真菌症と診断した．術後療法として2ヵ月間ボリコナゾールを内服し，術後18ヵ月現在再発は認めず，外来経過観察中である．Scedosporium apiospermumによる稀な肺感染症の1例を経験したので，報告する． …
NAID 130004839532

落葉状天疱瘡に対する免疫抑制療法中に生じたScedosporium apiospermumによる深在性皮膚真菌症の1例

竹内明子,濱口儒人,藤本学 [他]
日本皮膚科学会雑誌 = The Japanese journal of dermatology 124(6), 1135-1140, 2014-05
NAID 40020065439

「シュードアレシェリア症」

Pseudallescheria boydii
Scientific classification
Kingdom:	Fungi
Division:	Ascomycota
Class:	Sordariomycetes
Order:	Microascales
Family:	Microascaceae
Genus:	Pseudallescheria
Species:	P. boydii
Binomial name
	Pseudallescheria boydii; (Shear) McGinnis, A.A. Padhye & Ajello

　　[★]

英: pseudallescheriasis
関: 糸状真菌感染症、シュードアレシェリア属、スケドスポリウム症、(無性世代)Scedosporium apiospermum、(有性世代)Pseudallescheria boydii

「Scedosporium」

　　[★] セドス・リウム属

(真菌の一属)ドス・リウム属、Scedosporium属

[1] Pseudallescheria at the US National Library of Medicine Medical Subject Headings (MeSH)

[urlFilamentous_Fungi-2] "Filamentous Fungi".

[pmid18581978-3] Janda-Ulfig K, Ulfig K, Cano J, Guarro J (June 2008). "A study of the growth of Pseudallescheria boydii isolates from sewage sludge and clinical sources on tributyrin, rapeseed oil, biodiesel oil and diesel oil". Ann Agric Environ Med 15 (1): 45–9. PMID 18581978.

[pmid16772225-4] Guarro J, Kantarcioglu AS, Horré R, et al. (June 2006). "Scedosporium apiospermum: changing clinical spectrum of a therapy-refractory opportunist". Med. Mycol. 44 (4): 295–327. doi:10.1080/13693780600752507. PMID 16772225.

[5] Wiederhold, N. P.; Lewis, R. E.; Wiederhold, N. P.; Lewis, R. E. (2009). "Antifungal activity againstScedosporiumspecies and novel assays to assess antifungal pharmacodynamics against filamentous fungi". Medical Mycology 47 (4): 422–432. doi:10.1080/13693780802510224. PMID 19058049. edit

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案内

Scedosporium apiospermum