San Miguel sea lion virus

サンミゲルアシカウイルス、San Miguelアシカウイルス

関

vesicular exanthema of swine virus、VESV

WordNet

1. a harmful or corrupting agency; "bigotry is a virus that must not be allowed to spread"; "the virus of jealousy is latent in everyone"
2. (virology) ultramicroscopic infectious agent that replicates itself only within cells of living hosts; many are pathogenic; a piece of nucleic acid (DNA or RNA) wrapped in a thin coat of protein
3. a software program capable of reproducing itself and usually capable of causing great harm to files or other programs on the same computer; "a true virus cannot spread to another computer without human assistance" (同)computer virus
4. turbulent water with swells of considerable size; "heavy seas"
5. a division of an ocean or a large body of salt water partially enclosed by land
6. large gregarious predatory feline of Africa and India having a tawny coat with a shaggy mane in the male (同)king of beasts, Panthera_leo
7. a celebrity who is lionized (much sought after) (同)social lion
8. the 19th letter of the Roman alphabet (同)s
9. French writer known for works concerning womens rights and independence (1804-1876) (同)George Sand, Amandine Aurore Lucie Dupin, Baroness Dudevant

PrepTutorEJDIC

1. ビールス,ろ過性病原体
2. 《通例the~》《しばしば複数形で単数扱い》『海』,海洋 / 〈C〉《固有名詞につけるときはS-》(部分的に陸地に囲まれた)海,…海 / (波の状態から見た)海面,湖面,水面;(海・湖などの)波;大波,高波 / 〈U〉《the ~》船乗り(水兵)の仕事,海上生活 / 《a ~》大量(の…),たくさん(の…)《+『of』+『名』》
3. 『ライオン』,しし / (ライオンのように)勇猛な人 / 名士,人気者,花形 / (英国の象徴としての)ライオン;しし紋
4. sulfurの化学記号 / {略}South[ern]

UpToDate Contents

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• 1. ウイルスが誘発する喘鳴および喘息：概要role of viruses in wheezing and asthma an overview [show details]
  …Wheezing with viral infections, particularly respiratory syncytial virus (RSV) and human rhinovirus (RV), may predispose infants and young children to develop asthma later in life . Viruses, including coronaviruses …
• 2. ウイルス性関節炎：評価法およびマネージメントviral arthritis approach to evaluation and management [show details]
  … accompaniments to viral infections. The viral infections that most commonly have arthritis and/or arthralgias as a manifestation include parvovirus, hepatitis B, hepatitis C, rubella, Epstein-Barr virus (EBV), the …
• 3. ウイルス性筋炎の概要overview of viral myositis [show details]
  … immunodeficiency virus (HIV) Dengue virus ; The mechanism of muscle necrosis in acute viral myositis is unknown. The following possibilities have been proposed: Direct invasion of muscle tissue by the viral agent …
• 4. 慢性C型肝炎ウイルス感染のマネージメントの概要overview of the management of chronic hepatitis c virus infection [show details]
  …of patients with chronic hepatitis C virus (HCV) infection involves assessing the extent of liver disease, assessing other viral and host factors (including viral genotype, liver fibrosis stage, history …
• 5. 小児におけるA型肝炎ウイルス感染の概要overview of hepatitis a virus infection in children [show details]
  …nonenveloped RNA virus that belongs to the Heparnavirus genus of the Picornaviridae. Four well-defined genotypes of HAV have been described in humans, yet they belong to a single serotype . The virus is stable …

English Journal

• Development and evaluation of multiplex RT-LAMP assays for rapid and sensitive detection of foot-and-mouth disease virus.

• Yamazaki W, Mioulet V, Murray L, Madi M, Haga T, Misawa N, Horii Y, King DP.Author information Institute for Animal Health, Pirbright Laboratory, Ash Road, Pirbright, Surrey GU24 0NF, United Kingdom. yamazakiw@cc.miyazaki-u.ac.jpAbstractThis paper describes the evaluation of four novel real-time multiplex reverse transcription loop-mediated isothermal amplification (RT-LAMP) assays for rapid and sensitive diagnosis of foot-and-mouth disease (FMD). In order to overcome the genetic diversity of FMD viruses (FMDV), these multiplex RT-LAMP assay pairs were established by combining four newly designed primer sets with two primer sets that had been previously published. Using a real-time turbidimeter to detect amplification products and a panel of 300 samples collected throughout the world over a 78-year period, the performance of the multiplex RT-LAMP assays was compared with a FMDV-specific real-time RT-PCR assay. The most successful of the four multiplex RT-LAMP assays achieved a diagnostic sensitivity and specificity of 98.0% and 98.1%, and did not falsely detect FMDV in known negatives or samples containing swine vesicular disease virus, vesicular stomatitis virus or vesicular exanthema of swine virus. Furthermore, the analytical sensitivity of this multiplex RT-LAMP assay was at least as good as the individual component RT-LAMP tests. This is the first report of the development of a multiplex RT-LAMP to accommodate the high sequence variability encountered in RNA virus genomes and these results support the use of RT-LAMP as a cost-effective tool for simple diagnosis of FMD.
• Journal of virological methods.J Virol Methods.2013 Sep;192(1-2):18-24. doi: 10.1016/j.jviromet.2013.03.018. Epub 2013 Apr 12.
• This paper describes the evaluation of four novel real-time multiplex reverse transcription loop-mediated isothermal amplification (RT-LAMP) assays for rapid and sensitive diagnosis of foot-and-mouth disease (FMD). In order to overcome the genetic diversity of FMD viruses (FMDV), these multiplex RT-
• PMID 23583488

• Epitope insertion at the N-terminal molecular switch of the rabbit hemorrhagic disease virus T = 3 capsid protein leads to larger T = 4 capsids.

• Luque D, González JM, Gómez-Blanco J, Marabini R, Chichón J, Mena I, Angulo I, Carrascosa JL, Verdaguer N, Trus BL, Bárcena J, Castón JR.Author information Department of Structure of Macromolecules, Centro Nacional de Biotecnología/CSIC, Cantoblanco, Madrid, Spain.AbstractViruses need only one or a few structural capsid proteins to build an infectious particle. This is possible through the extensive use of symmetry and the conformational polymorphism of the structural proteins. Using virus-like particles (VLP) from rabbit hemorrhagic disease virus (RHDV) as a model, we addressed the basis of calicivirus capsid assembly and their application in vaccine design. The RHDV capsid is based on a T=3 lattice containing 180 identical subunits (VP1). We determined the structure of RHDV VLP to 8.0-Å resolution by three-dimensional cryoelectron microscopy; in addition, we used San Miguel sea lion virus (SMSV) and feline calicivirus (FCV) capsid subunit structures to establish the backbone structure of VP1 by homology modeling and flexible docking analysis. Based on the three-domain VP1 model, several insertion mutants were designed to validate the VP1 pseudoatomic model, and foreign epitopes were placed at the N- or C-terminal end, as well as in an exposed loop on the capsid surface. We selected a set of T and B cell epitopes of various lengths derived from viral and eukaryotic origins. Structural analysis of these chimeric capsids further validates the VP1 model to design new chimeras. Whereas most insertions are well tolerated, VP1 with an FCV capsid protein-neutralizing epitope at the N terminus assembled into mixtures of T=3 and larger T=4 capsids. The calicivirus capsid protein, and perhaps that of many other viruses, thus can encode polymorphism modulators that are not anticipated from the plane sequence, with important implications for understanding virus assembly and evolution.
• Journal of virology.J Virol.2012 Jun;86(12):6470-80. doi: 10.1128/JVI.07050-11. Epub 2012 Apr 4.
• Viruses need only one or a few structural capsid proteins to build an infectious particle. This is possible through the extensive use of symmetry and the conformational polymorphism of the structural proteins. Using virus-like particles (VLP) from rabbit hemorrhagic disease virus (RHDV) as a model,
• PMID 22491457

• Multiplex RT-PCR detection and microarray typing of vesicular disease viruses.

• Lung O, Fisher M, Beeston A, Hughes KB, Clavijo A, Goolia M, Pasick J, Mauro W, Deregt D.Author information Lethbridge Laboratory, National Centres for Animal Disease, Canadian Food Inspection Agency, Township Road 9-1, Lethbridge, Alberta T1J 3Z4, Canada. oliver.lung@inspection.gc.caAbstractA vesicular disease multiplex reverse transcription (RT)-PCR with an accompanying microarray assay was developed for simultaneous detection and typing of foot-and-mouth disease virus (FMDV) and vesicular stomatitis virus (VSV), and for the detection of swine vesicular disease virus (SVDV) and vesicular exanthema of swine virus (VESV). The multiplex RT-PCR successfully detected viral RNA from a collection of 49 strains of vesicular viruses, including multiple strains from all seven serotypes of FMDV and both serotypes of VSV. The multiplex RT-PCR was also able to produce amplified products from the RNA genome of all four viruses simultaneously in mixed samples. An indirect (post-PCR labelling) amplicon labelling method and a direct (concurrent labelling with PCR) amplicon labelling method were compared for the purpose of microarray detection and typing. Accurate detection and typing was achieved with all strains tested in the microarray assay which utilized 163 virus- and serotype-specific probes. It was observed that microarray increased detection for some samples compared to using multiplex RT-PCR alone. This was most likely due to signal amplification resulting from fluorescent labelling. The limit of detection of the microarray assay was as low as 4.6TCID(50)/mL for FMDV. No amplification products or microarray reactivity was observed with non-target livestock pathogens tested or with samples collected from healthy cattle, sheep and pigs. All FMDV and VSV serotypes were detected as early as 2 days post-inoculation from oral swabs obtained from cattle infected experimentally.
• Journal of virological methods.J Virol Methods.2011 Aug;175(2):236-45. doi: 10.1016/j.jviromet.2011.05.023. Epub 2011 May 19.
• A vesicular disease multiplex reverse transcription (RT)-PCR with an accompanying microarray assay was developed for simultaneous detection and typing of foot-and-mouth disease virus (FMDV) and vesicular stomatitis virus (VSV), and for the detection of swine vesicular disease virus (SVDV) and vesicu
• PMID 21620898

Japanese Journal

• イヌとネコに由来する各種カリシウイルスのRNAポリメラーゼ遺伝子の比較解析

• 橋本 美知留,Roerink Frank,遠矢 幸伸 [他],望月 雅美
• The journal of veterinary medical science 61(6), 603-608, 1999-06-25
• カリシウイルスは人や多くの動物種に感染し,それぞれの宿主において特徴的な症状を起こす.ネコカリシウイルス(FCV)は主にネコの呼吸器病の病原体であり,人カリシウイルスは下痢症因子である.さらに,FCVや新たに検出されたイヌカリシウイルス(CaCV)においても,これらの動物種の下痢症病原体としての可能性が示唆されてきた.本研究では,下痢症のイヌに由来するカリシウイルスであるCaCv No.48株とF …
• NAID 110003920096

• Genetic Analysis of the RNA Polymerase Gene of Caliciviruses from Dogs and Cats.

• HASHIMOTO Michiru,ROERINK Frank,TOHYA Yukinobu,MOCHIZUKI Masami
• Journal of Veterinary Medical Science 61(6), 603-608, 1999
• … In phylogenetic analysis, CaCV No. 48 strain grouped as a distinct branch sharing ancestral roots with San Miguel sea lion virus, and FCVs formed one compact group in which Sapporo/283 strain was included. …
• NAID 130000437284

• Relationship of San Miguel sea lion virus to other members of the calicivirus group

• BURROUGHS N
• Intervirology 10, 51-59, 1978
• NAID 30038895601

Related Links

• San Miguel sea lion virus fed to mink and pigs.

Abstract Mink became infected with San Miguel sea lion virus when fed ground meat from seal carcasses showing vesicular-like lesions in the skin. The mink also contracted the infection when they were fed San Miguel sea lion virus ...

• San Miguel sea lion virus | definition of San Miguel sea lion ...

San Mi·guel sea li·on vi·rus a calicivirus, family Caliciviridae, first isolated from sea lions on San Miguel island off the California coast; the virus is indistinguishable from the vesicular exanthema of swine virus both biophysically and ...

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★リンクテーブル★

リンク元	「サンミゲルアシカウイルス」「VESV」「San Miguelアシカウイルス」「vesicular exanthema of swine virus」
関連記事	「S」「lion」「sea」「virus」

「サンミゲルアシカウイルス」

　　[★]

英

San Miguel sea lion virus

関

ブタ水疱疹ウイルス、San Miguelアシカウイルス

「VESV」

　　[★]

• ブタ水疱疹ウイルス

関

San Miguel sea lion virus、vesicular exanthema of swine virus

「San Miguelアシカウイルス」

　　[★]

英

San Miguel sea lion virus

関

サンミゲルアシカウイルス

「vesicular exanthema of swine virus」

　　[★]

• ブタ水疱疹ウイルス

関

San Miguel sea lion virus、VESV

「S」

　　[★]

• セリン serine
• 胸骨上縁

　 　

「lion」

　　[★]

ライオン

関

Panthera leo

　 　 　

「sea」

　　[★]

• 海

関

marine、ocean

　 　 　

「virus」

　　[★] ウイルス