shRNA-mediated Bmi-1 silencing sensitizes multiple myeloma cells to bortezomib.
Wu SQ, Xu ZZ, Niu WY, Huang HB, Zhan R.
International journal of molecular medicine.Int J Mol Med.2014 Aug;34(2):616-23. doi: 10.3892/ijmm.2014.1798. Epub 2014 Jun 6.
The introduction of bortezomib has resulted in a paradigm shift in the treatment of multiple myeloma (MM) and has contributed to the improved survival of patients with MM. Inevitably, resistance to therapy develops, and thus the clinical efficacy of bortezomib is hampered by drug resistance. The onc
Argonaute (Ago) proteins function in RNA silencing as components of the RNA-induced silencing complex (RISC). In lower organisms, the small interfering RNA and miRNA pathways diverge due in part to sorting mechanisms that direct distinct small RNA (sRNA) duplexes onto specific Ago-RISCs. However, su
The Journal of urology.J Urol.2014 Jan;191(1):186-92. doi: 10.1016/j.juro.2013.08.007. Epub 2013 Aug 13.
PURPOSE: We retrospectively analyzed our institutional incidence of hemorrhagic cystitis, identified risk factors, and examined associations of risk factors with disease severity and genitourinary complication rates.MATERIALS AND METHODS: We reviewed charts of all consecutive pediatric patients trea
2 meanings of RADLV acronym and RADLV abbreviation. Get the definition of RADLV by All Acronyms dictionary. Top Definition: Radiation Leukemia Virus. ... Most Popular APA All Acronyms. 2015. RadLV. Retrieved February 16 ...
Radiation Leukemia Virus; RadLV. On-line free medical diagnosis assistant. Ranked list of possible diseases from either several symptoms or a full patient history. A similarity measure between symptoms and diseases is provided.