WordNet

any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
ancient Egyptian sun god with the head of a hawk; a universal creator; he merged with the god Amen as Amen-Ra to become the king of the gods (同)Re

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1. プロテインS欠乏症：臨床症状および診断 protein s deficiency clinical manifestations and diagnosis
2. 幼児の食物蛋白誘発性直腸炎/大腸炎および腸疾患 food protein induced proctitis colitis and enteropathy of infancy
3. プロテインC欠乏症：臨床症状および診断 protein c deficiency clinical manifestations and diagnosis
4. 第V因子ライデンおよび活性化プロテインC抵抗性：臨床症状および診断 factor v leiden and activated protein c resistance clinical manifestations and diagnosis
5. 肥大型心筋症の遺伝学 genetics of hypertrophic cardiomyopathy

Rich1 negatively regulates the epithelial cell cycle, proliferation and adhesion by CDC42/RAC1-PAK1-Erk1/2 pathway.

Zhang J1, Wang J2, Zhou YF2, Ren XY3, Lin MM2, Zhang QQ2, Wang YH2, Li X2.
Cellular signalling.Cell Signal.2015 Sep;27(9):1703-12. doi: 10.1016/j.cellsig.2015.05.009. Epub 2015 May 22.
Rich1, a previously identified Rho GTPase-activating protein (RhoGAP), was found to have close relationship with Rho GTPase family members in multiple cellular processes in nervous cells and platelets. But the exact role of Rich1 in epithelial cells remains obscure. The present investigation demonst
PMID 26004135

Zhang G1, Zhao L2, Wang Y1, Shao J1, Cui J1, Lou Y1, Geng M1, Zhang N1, Chen YH3, Liu S4.
Biochimica et biophysica acta.Biochim Biophys Acta.2015 Aug;1852(8):1574-84. doi: 10.1016/j.bbadis.2015.04.018. Epub 2015 Apr 22.
Proliferation of vascular smooth muscle cells (VSMCs) plays an important role in restenosis, a disease characterized by smooth muscle cell hyperplasia and neointimal formation. How proliferation signals are controlled to avoid restenosis is not fully understood. Here we report that TIPE2, the tumor
PMID 25912734

A Rac1 GTPase is a critical factor in the immune response of shrimp (Litopenaeus vannamei) to Vibrio alginolyticus infection.

Cha GH1, Wang WN2, Peng T1, Huang MZ1, Liu Y1.
Developmental and comparative immunology.Dev Comp Immunol.2015 Aug;51(2):226-37. doi: 10.1016/j.dci.2015.04.004. Epub 2015 Apr 16.
The small GTPase Rac1 acts as a molecular switch for signal transduction that regulates various cellular functions. However, its functions in crustaceans remain unclear. In this study, a cDNA encoding a RAS GTPase (LvRac1) in the Pacific white shrimp (L. vannamei) was identified and characterized.
PMID 25892021

GDNF and endothelin 3 regulate migration of enteric neural crest-derived cells via protein kinase A and Rac1.

Goto Akihiro,Sumiyama Kenta,Kamioka Yuji,Nakasyo Eiji,Ito Keisuke,Iwasaki Mitsuhiro,Enomoto Hideki,Matsuda Michiyuki
The Journal of neuroscience : the official journal of the Society for Neuroscience 33(11), 4901-4912, 2013-03-13
… The faster-migrating cells at the wavefront exhibited lower protein kinase A (PKA) activity than did the slower-migrating trailing cells. … The activities of Rac1 and Cdc42 exhibited an inverse correlation with the PKA activity, and PKA activation decreased the Rac1 activity and migration velocity. …
NAID 120005323883

Toda Satoshi,Hanayama Rikinari,Nagata Shigekazu
Molecular and cellular biology 32(1), 118-125, 2012-01-00
… Ba/F3 transformants expressing T cell immunoglobulin- and mucin-domain-containing molecule 4 (Tim4), a type I membrane protein that specifically binds phosphatidylserine, efficiently bound apoptotic cells in a phosphatidylserine-dependent manner but did not engulf them. …
NAID 120005300448

Overexpression of CRKII increases migration and invasive potential in oral squamous cell carcinoma.

Yamada Shin-Ichi,Yanamoto Souichi,Kawasaki Goro,Rokutanda Satoshi,Yonezawa Hisanobu,Kawakita Akiko,Nemoto Takayuki K
Cancer Letters 303(2), 84-91, 2011-04-28
… Downregulation of CRKII expression also reduced the expression of Dock180, p130Cas, and Rac1, and the actin-associated scaffolding protein cortactin. …
NAID 120003001161