- ュードモナス科
WordNet
- type genus of the family Pseudomonodaceae (同)genus Pseudomonas
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/02/27 07:41:21」(JST)
wiki en
English Journal
- Serum-dependent enhancement of coxsackievirus B4-induced production of IFNα, IL-6 and TNFα by peripheral blood mononuclear cells.
- Alidjinou EK, Sané F, Engelmann I, Hober D.Author information Université Lille 2, Faculté de Médecine, CHRU, Laboratoire de Virologie EA3610, Loos-lez-Lille 59120, France.AbstractOnly a few reports have been published on the interactions between Coxsackievirus B4 (CVB4) and human peripheral blood mononuclear cells (PBMC) but have not been extensively documented. Human serum containing non-neutralizing anti-CVB4 antibodies increased CVB4-induced synthesis of IFNα by PBMC. In this study, we determined if CVB4 and human serum have the ability to activate inflammatory cytokines in addition to IFNα in PBMC cultures. PBMC from healthy donors were inoculated with infectious, inactivated CVB4 or with CVB4 incubated with dilutions of human serum or polyvalent IgG with anti-CVB4 activity. Levels of IFNα, TNFα, IL-6, IL-12, IFNγ and IL-10 in the cell-free supernatants of PBMC cultures were measured using ELISA. Infection was assessed by real-time PCR. PBMC inoculated with CVB4 produced inflammatory cytokines but not IFNα. When CVB4 was incubated with serum or IgG, IFNα was detected in the culture supernatants, and high concentrations of TNFα and IL-6 were measured. The concentrations of TNFα and IL-6 were not reduced in cultures inoculated with inactivated CVB4, whereas the IgG-dependent enhancement of IFNα, IL-6 and TNFα production with inactivated virus was suppressed. The potentiation of IFNα production was associated with a high intracellular viral load. Infectious and non-infectious CVB4 can induce the production of inflammatory cytokines but not IFNα by PBMC. High levels of IFNα, in addition to TNFα and IL-6, in culture supernatants were obtained when infectious CVB4 was combined with immune serum or IgG, and they were associated with high amounts of intracellular viral RNA.
- Journal of molecular biology.J Mol Biol.2013 Dec 13;425(24):5020-31. doi: 10.1016/j.jmb.2013.10.008. Epub 2013 Oct 11.
- Only a few reports have been published on the interactions between Coxsackievirus B4 (CVB4) and human peripheral blood mononuclear cells (PBMC) but have not been extensively documented. Human serum containing non-neutralizing anti-CVB4 antibodies increased CVB4-induced synthesis of IFNα by PBMC. In
- PMID 24120940
- Production of nano zinc, zinc sulphide and nanocomplex of magnetite zinc oxide by Brevundimonas diminuta and Pseudomonas stutzeri.
- Mirhendi M, Emtiazi G, Roghanian R.AbstractZnO (Zincite) nanoparticle has many industrial applications and is mostly produced by chemical reactions, usually prepared by decomposition of zinc acetate or hot-injection and heating-up method. Synthesis of semi-conductor nanoparticles such as ZnS (Sphalerite) by ultrasonic was previously reported. In this work, high-zinc tolerant bacteria were isolated and used for nano zinc production. Among all isolated microorganisms, a gram negative bacterium which was identified as Brevundimonas diminuta could construct nano magnetite zinc oxide on bacterial surface with 22 nm in size and nano zinc with 48.29 nm in size. A piece of zinc metal was immersed in medium containing of pure culture of B. diminuta. Subsequently, a yellow-white biofilm was formed which was collected from the surface of zinc. It was dried at room temperature. The isolated biofilm was analysed by X-ray diffractometer. Interestingly, the yield of these particles was higher in the light, with pH 7 at 23°C. To the best of the authors knowledge, this is the first report about the production of nano zinc metal and nano zinc oxide that are stable and have anti-bacterial activities with magnetite property. Also ZnS (sized 12 nm) produced by Pseudomonas stutzeri, was studied by photoluminescence and fluorescent microscope.
- IET nanobiotechnology / IET.IET Nanobiotechnol.2013 Dec;7(4):135-9. doi: 10.1049/iet-nbt.2012.0032.
- ZnO (Zincite) nanoparticle has many industrial applications and is mostly produced by chemical reactions, usually prepared by decomposition of zinc acetate or hot-injection and heating-up method. Synthesis of semi-conductor nanoparticles such as ZnS (Sphalerite) by ultrasonic was previously reported
- PMID 24206770
- Pseudomonas aeruginosa outer membrane vesicles modulate host immune responses by targeting the Toll-like receptor 4 signaling pathway.
- Zhao K, Deng X, He C, Yue B, Wu M.Author information Department of Biochemistry and Molecular Biology, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, North Dakota, USA.AbstractBacteria can naturally secrete outer membrane vesicles (OMVs) as pathogenic factors, while these vesicles may also serve as immunologic regulators if appropriately prepared. However, it is largely unknown whether Pseudomonas aeruginosa OMVs can activate inflammatory responses and whether immunization with OMVs can provide immune protection against subsequent infection. We purified and identified OMVs, which were then used to infect lung epithelial cells in vitro as well as C57BL/6J mice to investigate the immune response and the underlying signaling pathway. The results showed that OMVs generated from P. aeruginosa wild-type strain PAO1 were more cytotoxic to alveolar epithelial cells than those from quorum-sensing (QS)-deficient strain PAO1-ΔlasR. The levels of Toll-like receptor 4 (TLR4) and proinflammatory cytokines, including interleukin-1β (IL-1β) and IL-6, increased following OMV infection. Compared with lipopolysaccharide (LPS), lysed OMVs in which the membrane structures were broken induced a weak immune response. Furthermore, expression levels of TLR4-mediated responders (i.e., cytokines) were markedly downregulated by the TLR4 inhibitor E5564. Active immunization with OMVs or passive transfer of sera with a high cytokine quantity acquired from OMV-immunized mice could protect healthy mice against subsequent lethal PAO1 challenges (1.5 × 10(11) CFU). Collectively, these findings indicate that naturally secreted P. aeruginosa OMVs may trigger significant inflammatory responses via the TLR4 signaling pathway and protect mice against pseudomonal lung infection.
- Infection and immunity.Infect Immun.2013 Dec;81(12):4509-18. doi: 10.1128/IAI.01008-13. Epub 2013 Sep 30.
- Bacteria can naturally secrete outer membrane vesicles (OMVs) as pathogenic factors, while these vesicles may also serve as immunologic regulators if appropriately prepared. However, it is largely unknown whether Pseudomonas aeruginosa OMVs can activate inflammatory responses and whether immunizatio
- PMID 24082079
Japanese Journal
- Bacterial propagation in reusable water reservoirs in a humidified oxygen supply system
- KOBAYASHI Nobuharu,YAMAZAKI Tsutomu,OKA Yohko,YAMAGUCHI Toshiyuki,MAESAKI Shigefumi
- Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 12(3), 160-162, 2006-06-01
- NAID 10017608182
- Purification and Characterization of Inducible Cephalexin Synthesizing Enzyme in Gluconobacter oxydans
- Shiau Chia-Yang,Pai Shun-Chung,Lin Wen-Po [他],JI Dar-Der,LIU Yu-Tien
- Bioscience, biotechnology, and biochemistry 69(3), 463-469, 2005-03-23
- … Interestingly, the purified enzyme did not catalyze hydrolysis of its products, <I>e.g.</I>, cephalexin, cephradine, and ampicillin, in contrast to enzymes from other strains of <I>Pseudomonadaceae</I>. …
- NAID 130000030382
- Family I. Pseudomonadaceae
- PALLERONI N. J.
- BERGEY's Manual Systemic Bacteriology 1, 141-218, 1989
- NAID 10008465958
Related Links
- The Pseudomonadaceae is a family of bacteria that includes the genera Azomonas, Azomonotrichon, Azorhizophilus, Azotobacter, Cellvibrio, Mesophilobacter, Pseudomonas (the type genus), Rhizobacter, Rugamonas, and Serpens. ...
Related Pictures
★リンクテーブル★
| リンク元 | 「シュードモナス科」「Azotobacteraceae」 |