Peyton Rous

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1. an artificial language for international use that rejects all existing words and is based instead on an abstract analysis of ideas
2. United States pathologist who discovered viruses that cause tumors (1879-1970) (同)Peyton_Rous, Francis Peyton Rous

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/08/14 13:45:20」(JST)

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(Francis) Peyton Rous
Francis Peyton Rous
Born	October 5, 1879 Baltimore, Maryland
Died	February 16, 1970(1970-02-16) (aged 90) New York City
Nationality	United States
Fields	virology
Known for	oncoviruses
Notable awards	Nobel Prize in Physiology or Medicine (1966)

(Francis) Peyton Rous ForMemRS (October 5, 1879 – February 16, 1970) born in Baltimore, Maryland in 1879 and received his B.A. and M.D. from Johns Hopkins University. He was involved in the discovery of the role of viruses in the transmission of certain types of cancer. In 1966 he was awarded a Nobel Prize in Physiology or Medicine for his work.

As a pathologist he made his seminal observation, that a malignant tumor (specifically, a sarcoma) growing on a domestic chicken could be transferred to another fowl simply by exposing the healthy bird to a cell-free filtrate, in 1911. This finding, that cancer could be transmitted by a virus (now known as the Rous sarcoma virus, a retrovirus), was widely discredited by most of the field's experts at that time. Since he was a relative newcomer, it was several years before anyone even tried to replicate his prescient results. Although clearly some influential researchers were impressed enough to nominate him to the Nobel Committee as early as 1926 (and in many subsequent years, until he finally received the award, 40 years later—this may be a record for the time between a discovery and a Nobel Prize).

In his later life he wrote biographies of Simon Flexner, and Karl Landsteiner.

References

Further reading

• Raju, T. N. (1999). "The Nobel Chronicles". The Lancet 354 (9177): 520–527. doi:10.1016/S0140-6736(05)75563-X. PMID 10465213. 
• Dulbecco, R. (1976). "Francis Peyton Rous". Biographical memoirs. National Academy of Sciences (U.S.) 48: 275–306. PMID 11615657. 
• "Francis Peyton Rous, M.D. Johns Hopkins". Lancet 1 (7644): 477. 1970. PMID 4189793. 
• Sulek, K. (1969). "Nobel prize for Francis Peyton Rous in 1966 for the discovery of carcinogenic viruses and for Charles Huggins for the introduction of hormones for treatment of neoplasms". Wiadomosci lekarskie (Warsaw, Poland : 1960) 22 (12): 1161–1162. PMID 4896432. 
• Datta, R. K.; Datta, B. (1967). "Nobel prize winners in medicine". Journal of the Indian Medical Association 48 (1): 41–42. PMID 5342283. 
• Graffi, A. (1966). "Francis Peyton Rous". Deutsche medizinische Wochenschrift (1946) 91 (51): 2309–2310. PMID 5333372. 
• Kreyberg, L. (1966). "Nobel prize in physiology and medicine 1966 (Rous FP)". Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 86 (22): 1565. PMID 4859882. 
• "Nobel Prize". BMJ 2 (5520): 964–961. 1966. doi:10.1136/bmj.2.5520.964. 
• Rhoads, C. P. (1959). "Citation and presentation of the Academy Medal to F. Peyton Rous". Bulletin of the New York Academy of Medicine 35 (4): 216–219. PMC 1806149. PMID 13629203. 

External links

• Nobel Lectures, Physiology or Medicine 1963–1970, Elsevier Publishing Company, Amsterdam, 1972

English Journal

• The fascinating germ theories on cancer pathogenesis.

• Tsoucalas G1, Laios K, Karamanou M, Gennimata V, Androutsos G.
• Journal of B.U.ON. : official journal of the Balkan Union of Oncology.J BUON.2014 Jan-Mar;19(1):319-23.
• For more than 100 years, the germ theory of cancer, proposing that microorganisms were at the origin of the disease, dominated medicine. Several eminent scientists like Etienne Burnet, Mikhail Stepanovich Voronin, Charles-Louis Malassez, and Francis-Peyton Rous argued on the pathogenesis presenting
• PMID 24659685

• Who is this man? Francis Peyton Rous.

• Kumar P1, Murphy FA.
• Emerging infectious diseases.Emerg Infect Dis.2013 Apr;19(4):661-3. doi: 10.3201/eid1904.130049.
• PMID 23751005

• SRC points the way to biomarkers and chemotherapeutic targets.

• Krishnan H1, Miller WT, Goldberg GS.
• Genes & cancer.Genes Cancer.2012 May;3(5-6):426-35. doi: 10.1177/1947601912458583.
• The role of Src in tumorigenesis has been extensively studied since the work of Peyton Rous over a hundred years ago. Src is a non-receptor tyrosine kinase that plays key roles in signaling pathways controlling tumor cell growth and migration. Src regulates the activities of numerous molecules to in
• PMID 23226580

Japanese Journal

• Dr.Peyton Rous(世界の研究者-16-)

• 伊藤 洋平
• 日本臨床 26(4), 965-967, 1968-04
• NAID 40018376269

• 生理学および医学賞Peyton ROUS,Charles HUGGINS (1966年度NOBEL賞)

• 桑田 次男
• 科学 36(12), 687-688, 1966-12
• NAID 40017543159