関: sodium stibogluconate

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1. 皮膚リーシュマニア症の治療 treatment of cutaneous leishmaniasis
2. 抗原虫治療 antiprotozoal therapies
3. 内臓リーシュマニア症の治療 treatment of visceral leishmaniasis
4. 消化管間質腫瘍に対する補助化学療法および術前補助化学療法としてのイマチニブ adjuvant and neoadjuvant imatinib for gastrointestinal stromal tumors
5. 内臓リーシュマニア症の臨床症状および診断 clinical manifestations and diagnosis of visceral leishmaniasis

English Journal

Characterization of the Proliferating Cell Nuclear Antigen of Leishmania donovani Clinical Isolates and Its Association with Antimony Resistance.

Tandon R1, Chandra S2, Baharia RK1, Das S1, Misra P1, Kumar A1, Siddiqi MI2, Sundar S3, Dube A4.
Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2014 Jun;58(6):2997-3007. Epub 2014 Mar 10.
Previously, through a proteomic analysis, proliferating cell nuclear antigen (PCNA) was found to be overexpressed in the sodium antimony gluconate (SAG)-resistant clinical isolate compared to that in the SAG-sensitive clinical isolate of Leishmania donovani. The present study was designed to explore
PMID 24614385

Elucidation of cellular mechanisms involved in experimental paromomycin resistance in Leishmania donovani.

Bhandari V1, Sundar S, Dujardin JC, Salotra P.
Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2014 May;58(5):2580-5. doi: 10.1128/AAC.01574-13. Epub 2014 Feb 18.
Leishmania donovani is the causative agent of the potentially fatal disease visceral leishmaniasis (VL). Chemotherapeutic options available to treat VL are limited and often face parasite resistance, inconsistent efficacy, and toxic side effects. Paromomycin (PMM) was recently introduced to treat VL
PMID 24550335

Diagnosis and management of oral leishmaniasis--case series and literature review.

Nadler C1, Enk CD2, Leon GT3, Samuni Y4, Maly A5, Czerninski R6.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.J Oral Maxillofac Surg.2014 May;72(5):927-34. doi: 10.1016/j.joms.2013.10.021. Epub 2013 Nov 5.
The worldwide prevalence of leishmaniasis is increasing because of ecologic changes and increased medical profession awareness. Furthermore, solitary cases have been recently reported in Western countries. The authors describe the epidemiology, mode of transmission, and diagnosis of leishmaniasis an
PMID 24480757

Japanese Journal

27 薬用植物における抗リーシュマニア活性化合物の探索研究(口頭発表の部)

天然有機化合物討論会講演要旨集 (52), 157-162, 2010-09-01
NAID 110009757751

Proanthocyanidins and Related Compounds:Antileishmanial Activity and Modulatory Effects on Nitric Oxide and Tumor Necrosis Factor-α-Release in the Murine Macrophage-Like Cell Line RAW 264.7

Biological & pharmaceutical bulletin 24(9), 1016-1021, 2001-09-01
NAID 110003638611

Pentostam induces resistance to antimony and the preservative chlorocresol in Leishmania donovani promastigotes and axenically grown amastigotes

Antimicrob Agents Chemother 41, 1064-1068, 1997
NAID 80009594320

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