NNNS

English Journal

A randomized-controlled trial pilot study examining the neurodevelopmental effects of a 5-week m technique intervention on very preterm infants.

Smith JR1, McGrath J, Brotto M, Inder T.
Advances in neonatal care : official journal of the National Association of Neonatal Nurses.Adv Neonatal Care.2014 Jun;14(3):187-200. doi: 10.1097/ANC.0000000000000093.
PURPOSE: To systematically test the cumulative effect of the M Technique on infant neurodevelopment in hospitalized very preterm infants.DESIGN: A pilot randomized controlled trial (RCT).SUBJECTS: Twenty very preterm infants (<30 weeks gestation with average birth weights <1000 g) were randoml
PMID 24858669

Sex-specific associations between placental leptin promoter DNA methylation and infant neurobehavior.

Lesseur C1, Armstrong DA2, Murphy MA3, Appleton AA3, Koestler DC3, Paquette AG2, Lester BM4, Marsit CJ5.
Psychoneuroendocrinology.Psychoneuroendocrinology.2014 Feb;40:1-9. doi: 10.1016/j.psyneuen.2013.10.012. Epub 2013 Oct 30.
BACKGROUND: Leptin (LEP) is a hormone central for energy homeostasis and has been implicated in neurodevelopment. This adipokine is produced by the placenta and is epigenetically regulated by promoter DNA methylation. Recent evidence has suggested a role for LEP in behavioral development. In this st
PMID 24485470

Alterations in brain structure and neurodevelopmental outcome in preterm infants hospitalized in different neonatal intensive care unit environments.

Pineda RG1, Neil J2, Dierker D3, Smyser CD4, Wallendorf M5, Kidokoro H6, Reynolds LC7, Walker S7, Rogers C8, Mathur AM6, Van Essen DC3, Inder T2.
The Journal of pediatrics.J Pediatr.2014 Jan;164(1):52-60.e2. doi: 10.1016/j.jpeds.2013.08.047. Epub 2013 Oct 17.
OBJECTIVE: To evaluate associations between neonatal intensive care unit (NICU) room type (open ward and private room) and medical outcomes; neurobehavior, electrophysiology, and brain structure at hospital discharge; and developmental outcomes at 2 years of age.STUDY DESIGN: In this prospective lon
PMID 24139564