マイコプラズマ・ハイオシノビエ、マイコプラズマ・ヒオシノビエ
WordNet
- any of a group of small parasitic bacteria that lack cell walls and can survive without oxygen; can cause pneumonia and urinary tract infection
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English Journal
- Optimization of an antibiotic sensitivity assay for Mycoplasma hyosynoviae and susceptibility profiles of field isolates from 1997 to 2011.
- Schultz KK, Strait EL, Erickson BZ, Levy N.Author information Veterinary Diagnostic & Production Animal Medicine, Iowa State University, College of Veterinary Medicine, 1600 South 16th St., Ames, IA 50011, USA. kschultz@iastate.eduAbstractMycoplasma hyosynoviae is a common agent responsible for polyarthritis leading to decreased production in swine herds worldwide. Antimicrobial agents are used to combat infections; however breakpoints for M. hyosynoviae have not yet been established. A number of methods have previously been utilized to analyze minimum inhibitory concentrations (MICs) for antibiotics against M. hyosynoviae; however these techniques as currently described are not easily standardized between laboratories. A dry microbroth dilution method was conducted to compare the minimum inhibitory concentrations (MICs) for 18 antibiotics, representative of different classes, against 24 recent isolates (23 field isolates and the type strain) of M. hyosynoviae. The MICs were determined using standard, commercially available 96-well Sensititre(®) plates containing various freeze-dried antibiotics at a range of concentrations appropriate to their potency. Clindamycin (CLI), a lincosamide antibiotic, showed the highest activity and most consistent inhibition for all isolates with an MIC(50) of ≤ 0.12 μg/ml. Tiamulin (TIA), a pleuromutilin derivative, exhibited an MIC(50) of ≤ 0.25 μg/ml. The isolates had similar levels of susceptibility to the quinolones, enrofloxacin (ENRO) and danofloxacin (DANO), exhibiting an MIC(50) of 0.25 μg/ml and 0.5 μg/ml, respectively. For the macrolides, the MIC(50) for tylosin (TYLT) and tilmicosin (TIL) was ≤ 0.25 μg/ml and ≤ 2 μg/ml respectively, but was ≤ 16 μg/ml for tulathromycin (TUL). For the aminoglycosides, the MIC(50) for gentamicin (GEN) was ≤ 0.5 μg/ml, while spectinomycin (SPE) and neomycin (NEO) had an MIC(50) of ≤ 4 μg/ml. The tetracyclines, oxytetracycline (OXY) and chlortetracycline (CTET) both had an MIC(50) of ≤ 2 μg/ml. Florfenicol (FFN) exhibited a MIC(50) of ≤ 1 μg/ml. All isolates were resistant to penicillin (PEN), ampicillin (AMP), ceftiofur (TIO), trimethoprim/sulfamethoxazole (SXT), and sulphadimethoxine (SDM) at all concentrations. Within the isolates tested, there was a range of sensitivity detected, with some isolates being overall more resistant while others appeared more susceptible. Further research is required to demonstrate how this MIC data correlates to clinical efficacy of the various antibiotics in the field.
- Veterinary microbiology.Vet Microbiol.2012 Jul 6;158(1-2):104-8. doi: 10.1016/j.vetmic.2012.02.002. Epub 2012 Feb 11.
- Mycoplasma hyosynoviae is a common agent responsible for polyarthritis leading to decreased production in swine herds worldwide. Antimicrobial agents are used to combat infections; however breakpoints for M. hyosynoviae have not yet been established. A number of methods have previously been utilized
- PMID 22397937
- Comparison of detection procedures of Mycoplasma hyopneumoniae, Mycoplasma hyosynoviae, and Mycoplasma hyorhinis in lungs, tonsils, and synovial fluid of slaughtered pigs and their distributions in Thailand.
- Makhanon M, Tummaruk P, Thongkamkoon P, Thanawongnuwech R, Prapasarakul N.Author information Department of Veterinary Microbiology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand. metta.makhanon@novartis.comAbstractThe aim of this study was to investigate whether direct PCR (DP) gave similar results to culture prior to PCR (CPP) for detecting mycoplasmas in different types of pig tissues. A total of 724 samples obtained from lungs, tonsils, or synovial fluids from 270 slaughtered pigs were used. The history of clinical signs, lung score, and the presence of joint lesions were recorded during sample collection. The rates of detection of Mycoplasma hyopneumoniae, Mycoplasma hyosynoviae, and Mycoplasma hyorhinis using both procedures were evaluated. The overall prevalences of M. hyopneumoniae, M. hyosynoviae, and M. hyorhinis were 40.3%, 12.3%, and 64.6%, respectively, and the detection rate depended on the sample type and the procedure used. With lung tissue, DP gave a higher detection rate for M. hyopneumoniae (77.4%) than CPP (38.5%). M. hyorhinis was detected by CPP at 15.6% and 18.1% and by DP at 31.5% and 5.2%, respectively. The positive rate derived from tonsil from CPP was closed to that of DP. Using synovial fluid could not yield any positive M. hyorhinis from CPP whereas 37.2% was positive from DP. In contrast, using sample tissue from lung and tonsil by CPP could show much higher positive number than that of DP. There was a significant relationship between joint lesion and M. hyorhinis detection by DP (P < 0.05) but not for M. hyosynoviae and M. hyorhinis detected by CPP. We speculated that lung was a proper sample for M. hyopneumoniae and M. hyorhinis detection by DP and CPP, respectively. Tonsil was likely the community of persistent M. hyosynoviae and M. hyorhinis with highly detection by CPP. Synovial fluid was apparently unsuitable for mycoplasmal culture. The accuracy of mycoplasmal detection may depend upon the type of sample relevant to the detection procedure used.
- Tropical animal health and production.Trop Anim Health Prod.2012 Feb;44(2):313-8. doi: 10.1007/s11250-011-0022-z. Epub 2011 Nov 25.
- The aim of this study was to investigate whether direct PCR (DP) gave similar results to culture prior to PCR (CPP) for detecting mycoplasmas in different types of pig tissues. A total of 724 samples obtained from lungs, tonsils, or synovial fluids from 270 slaughtered pigs were used. The history of
- PMID 22116666
- Optimal combinations of acute phase proteins for detecting infectious disease in pigs.
- Heegaard PM, Stockmarr A, Piñeiro M, Carpintero R, Lampreave F, Campbell FM, Eckersall PD, Toussaint MJ, Gruys E, Sorensen NS.Author information Innate Immunology Group, National Veterinary Institute, Technical University of Denmark, 1790 Copenhagen V, Denmark. pmhh@vet.dtu.dk.AbstractThe acute phase protein (APP) response is an early systemic sign of disease, detected as substantial changes in APP serum concentrations and most disease states involving inflammatory reactions give rise to APP responses. To obtain a detailed picture of the general utility of porcine APPs to detect any disease with an inflammatory component seven porcine APPs were analysed in serum sampled at regular intervals in six different experimental challenge groups of pigs, including three bacterial (Actinobacillus pleuropneumoniae, Streptococcus suis, Mycoplasma hyosynoviae), one parasitic (Toxoplasma gondii) and one viral (porcine respiratory and reproductive syndrome virus) infection and one aseptic inflammation. Immunochemical analyses of seven APPs, four positive (C-reactive protein (CRP), haptoglobin (Hp), pig major acute phase protein (pigMAP) and serum amyloid A (SAA)) and three negative (albumin, transthyretin, and apolipoprotein A1 (apoA1)) were performed in the more than 400 serum samples constituting the serum panel. This was followed by advanced statistical treatment of the data using a multi-step procedure which included defining cut-off values and calculating detection probabilities for single APPs and for APP combinations. Combinations of APPs allowed the detection of disease more sensitively than any individual APP and the best three-protein combinations were CRP, apoA1, pigMAP and CRP, apoA1, Hp, respectively, closely followed by the two-protein combinations CRP, pigMAP and apoA1, pigMAP, respectively. For the practical use of such combinations, methodology is described for establishing individual APP threshold values, above which, for any APP in the combination, ongoing infection/inflammation is indicated.
- Veterinary research.Vet Res.2011 Mar 17;42:50. doi: 10.1186/1297-9716-42-50.
- The acute phase protein (APP) response is an early systemic sign of disease, detected as substantial changes in APP serum concentrations and most disease states involving inflammatory reactions give rise to APP responses. To obtain a detailed picture of the general utility of porcine APPs to detect
- PMID 21414190
Japanese Journal
- 2008～2011年にタイで分離されたMycoplasma hyosynoviaeの抗菌剤感受性
- THONGKAMKOON Pacharee,NARONGSAK Watcharachai,小林 秀樹 [他]
- 家畜衛生学雑誌 = The Japanese journal of animal hygiene 40(1), 1-6, 2014-04
- NAID 40020063649
- Mycoplasma hyosynoviaeおよびM. hyorhinisの薬剤感受性試験
- 小林 秀樹,Sonmez Nejdet,両角 徹雄 [他],三谷 賢治,伊東 伸宜,塩野 浩紀,山本 孝史
- The journal of veterinary medical science 58(11), 1107-1111, 1996-11-25
- … 日本国内において1980〜1995年にかけて出荷豚から分離したMycoplasma hyosynoviae 54株および1991〜1994年にかけて呼吸器症状を呈した子豚から分離したM. … 最も高い活性を示したのはチアムリンであり, その最小発育阻止濃度(MIC)はそれぞれ, M.hyosynoviaeで0.013〜0.1μg/ml(MIC_<90> … hyosynoviaeのうち2株と11株のM. …
- NAID 110003916655
- 生殖器・呼吸器症候群(PRRS)に罹患した仔豚の肺におけるMycoplasma hyorhinisの感染状況
- 小林 秀樹,両角 徹雄,宮本 千加子 [他],清水 実嗣,山田 俊冶,大橋 誠一,久保 正法,木村 久美子,三谷 賢冶,伊東 伸宣,山本 孝史
- The journal of veterinary medical science 58(2), 109-113, 1996-02-25
- … 生殖器・呼吸器症候群(PRRS)に罹患した仔豚の肺におけるマイコプラズマ(M.hyorhinis, M.hyosynoviae, M.hyopneumoniae)の感染状況を調べた. … 一方, 全供試豚のうち, M.hyopneumoniaeが分離されたのはわずか4頭にすぎず, M.hyosynoviaeは全く分離されなかった. …
- NAID 110003916467
Related Links
- Some herds never see clinical signs and some are plagued with it, especially in early finisher or when introducing new breeding stock. ... Infection of the pig by the tiny bacteria, Mycoplasma hyosynoviae, can be a real ...
- Mycoplasma Arthritis (Mycoplasma hyosynoviae infection) (277) This is caused by the tiny organism Mycoplasma hyosynoviae which is ubiquitous and most, if not all herds are infected with it. It is a respiratory spread ...
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