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a usually malignant tumor arising from connective tissue (bone or muscle etc.); one of the four major types of cancer

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1. 放射線関連肉腫 radiation associated sarcomas
2. 乳房肉腫：治療 breast sarcoma treatment
3. 転移性軟部組織肉腫の全身治療 systemic treatment of metastatic soft tissue sarcoma
4. 子宮肉腫：分類、臨床症状、および診断 uterine sarcoma classification clinical manifestations and diagnosis
5. 四肢および胸壁の原発性軟部組織肉腫の局所治療 local treatment for primary soft tissue sarcoma of the extremities and chest wall

Design, Synthesis, and Biological Evaluation of Unconventional Aminopyrimidine, Aminopurine, and Amino-1,3,5-triazine Methyloxynucleosides.

Fernández-Cureses G1, de Castro S, Jimeno ML, Balzarini J, Camarasa MJ.
ChemMedChem.ChemMedChem.2014 Nov 24. doi: 10.1002/cmdc.201402465. [Epub ahead of print]
Herein we describe a class of unconventional nucleosides (methyloxynucleosides) that combine unconventional nucleobases such as substituted aminopyrimidines, aminopurines, or aminotriazines with unusual sugars in their structures. The allitollyl or altritollyl derivatives were pursued as ribonucleos
PMID 25420933

MRNA and miRNA expression patterns associated to pathways linked to metal mixture health effects.

Martínez-Pacheco M1, Hidalgo-Miranda A, Romero-Córdoba S, Valverde M, Rojas E.
Gene.Gene.2014 Jan 10;533(2):508-14. doi: 10.1016/j.gene.2013.09.049. Epub 2013 Sep 27.
Metals are a threat to human health by increasing disease risk. Experimental data have linked altered miRNA expression with exposure to some metals. MiRNAs comprise a large family of non-coding single-stranded molecules that primarily function to negatively regulate gene expression post-transcriptio
PMID 24080485

Genetic Modeling of PIM Proteins in Cancer: Proviral Tagging and Cooperation with Oncogenes, Tumor Suppressor Genes, and Carcinogens.

Aguirre E1, Renner O1, Narlik-Grassow M1, Blanco-Aparicio C1.
Frontiers in oncology.Front Oncol.2014 May 15;4:109. doi: 10.3389/fonc.2014.00109. eCollection 2014.
The PIM proteins, which were initially discovered as proviral insertion sites in Moloney-murine leukemia virus infection, are a family of highly homologous serine/threonine kinases that have been reported to be overexpressed in hematological malignancies and solid tumors. The PIM proteins have also
PMID 24860787

Establishment of Modified Retroviral Vector Targeting X-Linked Severe Combined Immunodeficiency

Studies of Human Immunodeficiency Virus Type 1 (HIV-1) Protease Inhibitors. III. Structure-Activity Relationship of HIV-1 Protease Inhibitors Containing Cyclohexylalanylalanine Hydroxyethylene Dipeptide lsostere.

Studies of Human Immunodeficiency Virus Type 1 (HIV-1) Protease Inhibitors. III. Structure-Activity Relationship of HIV-1 Protease Inhibitors Containing Cyclohexylalanylalanine Hydroxyethylene Dipeptide Isostere