睡眠潜時反復検査, multiple sleep latency test
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/05/08 00:18:51」(JST)
[Wiki en表示]
| Multiple Sleep Latency Test |
| Intervention |
| ICD-9-CM |
89.18 |
| OPS-301 code |
1-795 |
|
[edit on Wikidata]
|
MSLT Scores
| Minutes |
Sleepiness |
| 0–5 |
Severe |
| 5–10 |
Troublesome |
| 10–15 |
Manageable |
| 15–20 |
Excellent |
The Multiple Sleep Latency Test (MSLT) is a sleep disorder diagnostic tool. It is used to measure the time elapsed from the start of a daytime nap period to the first signs of sleep, called sleep latency. The test is based on the idea that the sleepier people are, the faster they will fall asleep.
The MSLT is used extensively to test for narcolepsy, to distinguish between physical tiredness and true excessive daytime sleepiness, or to assess whether treatments for breathing disorders are working. Its main purpose is to discover how readily a person will fall asleep in a conducive setting, how consistent or variable this is, and the way they fall asleep in terms of REM sleep and other brain patterns. This can be used to identify and differentiate between various sleep problems.
The test consists of four or five 20-minute nap opportunities set two hours apart, often following an overnight sleep study. During the test, data such as the patient's brain waves, EEG, muscle activity, and eye movements are monitored and recorded. The entire test normally takes about 7 hours during the course of a day.
Contents
- 1 History
- 2 Typical procedure
- 3 References
- 4 External links
History
The Multiple Sleep Latency Test was created in 1977 by sleep pioneers William C. Dement and Mary Carskadon.[1][2][3][4] It developed out of repeating a project done in 1970 by Dr. Dement called the 90-minute day.[5] They informally called the 0–5 minute range the twilight zone due to its indication of extreme physical and mental impairment.
Typical procedure
Preparation: On the day of the test the patient is asked not to consume any stimulants, such as tea, coffee, colas, and chocolate.
- Often a formal sleep study has been performed the night before.
- Sometimes urine screening is done to make sure no substances exist in the subject's body that might interfere with sleep.
- The patient may be asked to fill out a pre-test questionnaire.
- Electrodes are attached to the patient's head to record brain waves.
- Electrodes are attached by the eyes to record eye movement.
- Electrodes are attached to the chin to detect muscle tone.
- Heart beat may also be monitored.
- The patient is asked to perform simple tasks to test that the equipment is working properly.
- The patient is asked to nap for 20 minutes, and then is awakened.
- The nap process is repeated every 2 hours for a total of four or five times.
- The patient may be asked to fill out a post-test questionnaire.
- A sleep technologist will gently place sensors on patient's head, face and chin. These sensors are connected to a computer. The sensors show when patient is asleep and awake, and transmit data used to determine when patient is in REM sleep. The nap trial begins when the lights are turned off.[6]
A clinical neurophysiologist, neurologist or sleep specialist will review the results and inform the patient or the patient's primary care physician of the interpretation of the test result in the context of the clinical problem.
References
- ^ Carskadon, M.A.; Dement, W.C. Sleep tendency: an objective measure of sleep loss. Sleep Research 6: 200, 1977.
- ^ Richardson, G.S.; Carskadon, M.A.; Flagg, W.; Van den Hoed, J.; Dement, W.C.; Mitler, M.M. Excessive daytime sleepiness in man: multiple sleep latency measurement in narcoleptic and control subjects. Electroencephalogr Clin Neurophysiol. 1978 Nov;45(5):621–627.
- ^ Carskadon, M.A.; Dement, W.C.; Mitler, M.M.; Roth, T.; Westbrook, P.R.; Keenan, S. Guidelines for the Multiple Sleep Latency Test (MSLT): a standard measure of sleepiness. Sleep 1986; 9:519–524
- ^ Thorpy, M.J.; Westbrook, P.; Ferber, R.; Fredrickson, P.; Mahowald, M.; Perez-Guerra, F.; Reite, M.; Smith, P. The clinical use of the Multiple Sleep Latency Test. Sleep 1992; 15:268–276.
- ^ Carskadon, M.A.; Dement, W.C. Sleep studies on a 90-minute day. Electroencephalogr. Clin. Neurophysiol. 39: 145–155, 1975.
- ^ "Multiple Sleep Latency Test (MSLT) - Testing Process & Results". American Academy of Sleep Medicine. Retrieved 8 September 2014.
External links
- Mary Carskadon's page on the MSLT [1]
UpToDate Contents
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English Journal
- Non-random temporal distribution of sleep onset REM periods in the MSLT in narcolepsy.
- Sansa G1, Falup-Pecurariu C2, Salamero M3, Iranzo A2, Santamaria J2.
- Journal of the neurological sciences.J Neurol Sci.2014 Jun 15;341(1-2):136-8. doi: 10.1016/j.jns.2014.03.039. Epub 2014 Mar 26.
- STUDY OBJECTIVES: The diagnosis of narcolepsy is supported by the presence of two or more sleep onset REM periods (SOREMPs) in the multiple latency sleep test (MSLT). The distribution of SOREMPs throughout the MSLT has not been systematically studied in narcolepsy. We studied the temporal distributi
- PMID 24735736
- The effects of armodafinil on objective sleepiness and performance in a shift work disorder sample unselected for objective sleepiness.
- Howard R1, Roth T, Drake CL.
- Journal of clinical psychopharmacology.J Clin Psychopharmacol.2014 Jun;34(3):369-73. doi: 10.1097/JCP.0000000000000136.
- BACKGROUND: Armodafinil is a medication used to treat excessive sleepiness in individuals with shift work disorder (SWD). In the present study, we investigate whether armodafinil can normalize nocturnal sleepiness in a group of typical SWD patients.METHODS: Participants were 12 night workers (aged 3
- PMID 24717254
- Narcolepsy and Predictors of Positive MSLTs in the Wisconsin Sleep Cohort.
- Goldbart A1, Peppard P2, Finn L2, Ruoff CM3, Barnet J4, Young T2, Mignot E3.
- Sleep.Sleep.2014 Jun 1;37(6):1043-51. doi: 10.5665/sleep.3758.
- STUDY OBJECTIVES: To study whether positive multiple sleep latency tests (MSLTs, mean sleep latency [MSL] ≤ 8 minutes, ≥ 2 sleep onset REM sleep periods [SOREMPs]) and/or nocturnal SOREMP (REM sleep latency ≤ 15 minutes during nocturnal polysomonography [NPSG]) are stable traits and can reflec
- PMID 24882899
Japanese Journal
- 中枢性過眠症と運転 (特集 運転パフォーマンスと睡眠問題)
- Brain Science(125)睡眠不足症候群,ナルコレプシーのPOMS,MSLTおよび睡眠不足症候群の前頭皮質機能
- PSG判定のより詳細な合意を求めて(第5回)過眠症の客観的評価法である睡眠潜時反復検査(MSLT)の精度を高めるための手法
Related Links
- MSLT(睡眠潜時反復検査)は、過度の日中の眠気を引き起こすような疾患（ナルコレプシーなど）及び日中の眠気を ... PSG（終夜睡眠ポリグラフ）検査：睡眠の状態を評価し、過眠の原因となる睡眠障害を調べます。 MSLT（睡眠潜 ...
- 昼間の睡眠評価 ～ MSLT ～ 昼間の眠気を計測するのはそれほど難しくはありません。脳波、特にα波の鑑別ができれば簡単に実施できます。 昼間の睡眠評価ではMSLT(Multiple Sleep Latency Test)という手法を利用します。
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