WordNet

the physiological state produced by a poison or other toxic substance (同)toxic condition, intoxication
the act of giving poison to a person or animal with the intent to kill

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Selective VIP Receptor Agonists Facilitate Immune Transformation for Dopaminergic Neuroprotection in MPTP-Intoxicated Mice.

Olson KE1, Kosloski-Bilek LM1, Anderson KM1, Diggs BJ2, Clark BE2, Gledhill JM Jr2, Shandler SJ2, Mosley RL1, Gendelman HE3.
The Journal of neuroscience : the official journal of the Society for Neuroscience.J Neurosci.2015 Dec 16;35(50):16463-78. doi: 10.1523/JNEUROSCI.2131-15.2015.
Vasoactive intestinal peptide (VIP) mediates a broad range of biological responses by activating two related receptors, VIP receptor 1 and 2 (VIPR1 and VIPR2). Although the use of native VIP facilitates neuroprotection, clinical application of the hormone is limited due to VIP's rapid metabolism and
PMID 26674871

Bee Venom Phospholipase A2, a Novel Foxp3+ Regulatory T Cell Inducer, Protects Dopaminergic Neurons by Modulating Neuroinflammatory Responses in a Mouse Model of Parkinson's Disease.

Chung ES1, Lee G1, Lee C1, Ye M1, Chung HS1, Kim H1, Bae SJ2, Hwang DS3, Bae H4.
Journal of immunology (Baltimore, Md. : 1950).J Immunol.2015 Nov 15;195(10):4853-60. doi: 10.4049/jimmunol.1500386. Epub 2015 Oct 9.
Foxp3-expressing CD4(+) regulatory T cells (Tregs) are vital for maintaining immune tolerance in animal models of various immune diseases. In the present study, we demonstrated that bee venom phospholipase A2 (bvPLA2) is the major BV compound capable of inducing Treg expansion and promotes the survi
PMID 26453752

[Early Stages of Parkinson's Disease: Comparative Characteristics of Sleep-Wakefulness Cycle in Patients and Model Animals].

Kovalzon VM, Ugrumov MV, Pronina TS, Dorokhov VB, Manolov AI, Dolgikh VV, Ukraintseva YV, Moiseenko LS, Poluektov MG, Kalinkin AL.
Fiziologiia cheloveka.Fiziol Cheloveka.2015 Nov-Dec;41(6):114-8.
The results of study of sleep-wakefulness cycle in experimental models of pre-clinical and early clinical stages of Parkinson's disease present and compared to some clinical examples. The conclusion is, the increase in activity level and decrease in total amount of slow wave and paradoxical sleep in
PMID 26859995