ルイス肺癌、(細胞株)イス肺癌細胞、Lewis肺癌細胞
- 関
- LLC
WordNet
- English critic and novelist; author of theological works and of books for children (1898-1963) (同)C. S. Lewis, Clive Staples Lewis
- United States athlete who won gold medals at the Olympics for his skill in sprinting and jumping (born in 1961) (同)Carl Lewis, Frederick Carleton Lewis
- United States rock star singer and pianist (born in 1935) (同)Jerry Lee Lewis
- United States labor leader who was president of the United Mine Workers of America from 1920 to 1960 and president of the Congress of Industrial Organizations from 1935 to 1940 (1880-1969) (同)John L. Lewis, John Llewelly Lewis
- United States explorer and soldier who lead led an expedition from St. Louis to the mouth of the Columbia River (1774-1809) (同)Meriwether Lewis
- United States novelist who satirized middle-class America in his novel Main Street (1885-1951) (同)Sinclair Lewis, Harry Sinclair Lewis
- either of two saclike respiratory organs in the chest of vertebrates; serves to remove carbon dioxide and provide oxygen to the blood
- any malignant tumor derived from epithelial tissue; one of the four major types of cancer
PrepTutorEJDIC
- 《しばしば複数形で》『肺』,肺臓
- がん,がん腫
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/08/25 03:41:23」(JST)
[Wiki en表示]
Lewis lung carcinoma is a tumor discovered by Dr. Margaret R. Lewis of the Wistar Institute in 1951. This tumor originated spontaneously as a carcinoma of the lung of a C57BL mouse. The tumor does not appear to be grossly hemorrhagic and the majority of the tumor tissue is a semifirm homogeneous mass.[1] It is also called 3LL and LLC and is used as a transplantable malignancy. It has been used in many studies.[2]
In 1975, Munson discovered that cannabinoids suppress Lewis lung carcinoma cell growth. The mechanism of this action was shown to be inhibition of DNA synthesis[3]Cannabinoids increase the life span of mice carrying Lewis lung tumors and decrease primary tumor size.[4] There are multiple modes of action.[5]
References
- ^ Cancer Chemother Rep 2 1972 Nov;(3)1:325
- ^ Teicher, Beverly A.; Andrews, Paul A. (2004). Anticancer drug development guide: preclinical screening, clinical trials, and approval. Humana Press. pp. 197–. ISBN 978-1-58829-228-5. Retrieved 31 July 2011.
- ^ Friedman MA (1977). "In vivo effects of cannabinoids on macromolecular biosynthesis in Lewis lung carcinomas.". Cancer Biochem Biophys. 2 (2): 51–4. PMID 616322.
- ^ Kogan NM (2005). "Cannabinoids and cancer.". Mini Rev Med Chem. 5 (10): 941–52. doi:10.2174/138955705774329555. PMID 16250836.
- ^ Portella G, Laezza C, Laccetti P, De Petrocellis L, Di Marzo V, Bifulco M (2003). "Inhibitory effects of cannabinoid CB1 receptor stimulation on tumor growth and metastatic spreading: actions on signals involved in angiogenesis and metastasis.". FASEB J 17 (12): 1771–3. doi:10.1096/fj.02-1129fje. PMID 12958205.
UpToDate Contents
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English Journal
- Fucoidan from Sargassum sp. and Fucus vesiculosus reduces cell viability of lung carcinoma and melanoma cells in vitro and activates natural killer cells in mice in vivo.
- Ale MT, Maruyama H, Tamauchi H, Mikkelsen JD, Meyer AS.SourceCenter for Bioprocess Engineering, Department of Chemical and Biochemical Engineering, Technical University of Denmark (DTU), Soltofts Plads Building 229, 2800 Kgs. Lyngby, Denmark.
- International journal of biological macromolecules.Int J Biol Macromol.2011 Oct 1;49(3):331-6. Epub 2011 May 23.
- Fucoidan is known to exhibit crucial biological activities, including anti-tumor activity. In this study, we examined the influence of crude fucoidan extracted from Sargassum sp. (MTA) and Fucus vesiculosus (SIG) on Lewis lung carcinoma cells (LCC) and melanoma B16 cells (MC). In vitro studies were
- PMID 21624396
- Inhibition of tumor angiogenesis in lung cancer by T4 phage surface displaying mVEGFR2 vaccine.
- Ren S, Fengyu, Zuo S, Zhao M, Wang X, Wang X, Chen Y, Wu Z, Ren Z.SourceDepartment of Clinical Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
- Vaccine.Vaccine.2011 Aug 5;29(34):5802-11. Epub 2011 Apr 9.
- Vascular endothelial growth factor (VEGF) has been known as a potential vasculogenic and angiogenic factor and its receptor (VEGFR2) is a major receptor to response to the angiogenic activity of VEGF. The technique that to break the immune tolerance of "self-antigens" associated with angiogenesis is
- PMID 21482223
Japanese Journal
- ビタミンDおよびビタミンKを分子基盤とするがんおよび骨粗鬆症治療薬の開発研究
- 中川 公恵
- ビタミン 85(1), 9-17, 2011-01-25
- … We used metastatic Lewis lung carcinoma cells expressing green fluorescent protein (LLC-GFP cells) and examined the metastatic activity in vitamin D receptor (VDR) null mutant (VDR-/-) mice and their wild-type counterparts (VDR+/+mice). … We showed that 1α,25(OH)_2D_3 inhibited the metastatic growth of lung cancer cells in a defined animal model. …
- NAID 110008440791
- Effect of Sunitinib Combined with Ionizing Radiation on Endothelial Cells
- ZHANG Hai-Ping,TAKAYAMA Koichi,SU Bo,JIAO Xiao-dong,LI Rui,WANG Jie-Jun
- Journal of radiation research 52(1), 1-8, 2011-01-16
- … Lewis lung carcinoma mouse model was built to examine the effect of combination therapy on endothelial cells in vivo. …
- NAID 10027418060
Related Links
- In 1975, Munson discovered that cannabinoids suppress Lewis lung carcinoma cell growth. The mechanism of this action was shown to be inhibition of DNA synthesisCannabinoids increase the life span of mice carrying Lewis lung tumors ...
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- 英
- Lewis lung carcinoma、LLC
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- ルイス肺癌、Lewis肺癌細胞
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- 英
- Lewis lung carcinoma
- 関
- ルイス肺癌細胞、Lewis肺癌細胞
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- 英
- Lewis lung carcinoma
- 関
- ルイス肺癌細胞、ルイス肺癌
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- 関
- Lewis lung carcinoma
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ルイス