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1. Skeletal dysplasias: Specific disorders
2. Skeletal dysplasias: Approach to evaluation
3. 性染色体異常 sex chromosome abnormalities
4. 小児および思春期における慢性の手首の疼痛の原因 causes of chronic wrist pain in children and adolescents
5. Clinical manifestations and diagnosis of Turner syndrome

English Journal

Diabetes gets on the nerves of the bone marrow niche.

Leri A1, Rota M.
Diabetes.Diabetes.2014 Apr;63(4):1185-7. doi: 10.2337/db13-1931.
PMID 24651801

Langer mesomelic dysplasia in early fetuses: two cases and a literature review.

Ambrosetti F1, Palicelli A, Bulfamante G, Rivasi F.Author information 1Anatomia Patologica, Oncologia, Reggio Emilia, Italy.AbstractIn the article, we report the autoptic, histological and radiographic phenotype of two fetuses (22 and 12 weeks) with Langer mesomelic dysplasia, a homozygous deletion of the 3' enhancer of the SHOX gene, and consanguineous parents affected by Léri-Weill dyschondrosteosis, performing a literature review of the primary forms of mesomelic dysplasia. A proper identification of the type of mesomelic dysplasia is important for genetic and reproductive counseling, estimation of child growth and prevention and/or treatment of complications. A competent pathologist could provide important diagnostic information, orienting or confirming the echographic or genetic suspect, sometimes suggesting diagnostic hypothesis concerning parental unidentified congenital syndromes.
Fetal and pediatric pathology.Fetal Pediatr Pathol.2014 Apr;33(2):71-83. doi: 10.3109/15513815.2013.807322. Epub 2013 Jul 24.
In the article, we report the autoptic, histological and radiographic phenotype of two fetuses (22 and 12 weeks) with Langer mesomelic dysplasia, a homozygous deletion of the 3' enhancer of the SHOX gene, and consanguineous parents affected by Léri-Weill dyschondrosteosis, performing a literature r
PMID 23883335

Cue-induced renewal of heroin place preference: involvement of the basolateral amygdala.

Cummins E1, Boughner E, Leri F.Author information 1Department of Psychology, University of Guelph, Guelph, Ontario, Canada.AbstractIt is well established that re-exposure to a context paired with the effects of drugs of abuse can renew extinguished drug seeking behavior. A context, however, typically includes several stimuli, which may differ in their ability to control drug-oriented behaviors. Hence, the primary objective of this study was to assess whether a heroin-induced place preference could be recovered by re-exposure to a contextual stimulus that was part of the conditioning context before extinction. The second objective was to explore the role of the basolateral nucleus of the amygdala (BLA) in this conditioned effect. Male Sprague-Dawley rats were injected with 3 mg/kg heroin and confined in a compartment that was distinguished by a variety of contextual stimuli, including a ceramic floor tile. During extinction, the floor stimulus was removed, and it was reintroduced for a drug-free test of preference. A control experiment evaluated the unconditioned preference for the floor stimulus. It was found that reintroduction of the floor stimulus caused the recovery of heroin place preference. This effect was not observed in rats infused in the BLA with muscimol (0.03 nmol) and baclofen (0.3 nmol) just prior to the test. These data suggest that an extinguished heroin place preference can be renewed by a contextual tactual stimulus that was part of the conditioning context, and that this process requires an intact BLA.
Neuroreport.Neuroreport.2014 Mar 26;25(5):297-302. doi: 10.1097/WNR.0000000000000084.
It is well established that re-exposure to a context paired with the effects of drugs of abuse can renew extinguished drug seeking behavior. A context, however, typically includes several stimuli, which may differ in their ability to control drug-oriented behaviors. Hence, the primary objective of t
PMID 24201450

Japanese Journal

Skeletal Deformity Associated with SHOX Deficiency

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Clinical Pediatric Endocrinology 23(3), 65-72, 2014
… SHOX haploinsufficiency due to mutations in the coding exons or microdeletions involving the coding exons and/or the enhancer regions accounts for approximately 80% and 2–16% of genetic causes of Leri-Weill dyschondrosteosis and idiopathic short stature, respectively. …
NAID 130004677667

Mechanisms of Myocardial Regeneration

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Circulation journal : official journal of the Japanese Circulation Society 74(1), 13-17, 2009-12-20
The plasticity of bone marrow-derived progenitor cells (BMPCs) and their ability to acquire the myocyte lineage and regenerate dead myocardium after infarction has been challenged. Similarly, although …
NAID 10025940855