KFERQタンパク
WordNet
- any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
PrepTutorEJDIC
- 蛋白(たんばく)質
UpToDate Contents
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English Journal
- Selective endosomal microautophagy is starvation-inducible in Drosophila.
- Mukherjee A1, Patel B1, Koga H1, Cuervo AM1,2,3, Jenny A1,2,3,4.
- Autophagy.Autophagy.2016 Aug 3:1-16. [Epub ahead of print]
- Autophagy delivers cytosolic components to lysosomes for degradation and is thus essential for cellular homeostasis and to cope with different stressors. As such, autophagy counteracts various human diseases and its reduction leads to aging-like phenotypes. Macroautophagy (MA) can selectively degrad
- PMID 27487474
- Regulation of amyloid precursor protein processing by its KFERQ motif.
- Park JS1, Kim DH1, Yoon SY1.
- BMB reports.BMB Rep.2016 Jun;49(6):337-42.
- Understanding of trafficking, processing, and degradation mechanisms of amyloid precursor protein (APP) is important because APP can be processed to produce β-amyloid (Aβ), a key pathogenic molecule in Alzheimer's disease (AD). Here, we found that APP contains KFERQ motif at its C-terminus, a cons
- PMID 26779997
- Translocation of interleukin-1β into a vesicle intermediate in autophagy-mediated secretion.
- Zhang M1, Kenny SJ2, Ge L1, Xu K2, Schekman R1.
- eLife.Elife.2015 Nov 2;4. pii: e11205. doi: 10.7554/eLife.11205.
- Recent evidence suggests that autophagy facilitates the unconventional secretion of the pro-inflammatory cytokine interleukin 1β (IL-1β). Here, we reconstituted an autophagy-regulated secretion of mature IL-1β (m-IL-1β) in non-macrophage cells. We found that cytoplasmic IL-1β associates with th
- PMID 26523392
Japanese Journal
- KFERQ配列は飢餓時における蛋白質分解のシグナル
Related Pictures
![IGF-1Rβ has KFERQ-like pentapeptide sequences. IGF-1R amino acidic | Download](https://1mg.info/0/u/a/1520.jpg)
![| Chaperone-mediated degradation of misfolded proteins. CMA is a | Download](https://1mg.info/0/u/a/1521.jpg)
![Hsc70-4 Deforms Membranes to Promote Synaptic Protein Turnover by Endosomal](https://1mg.info/0/u/a/1522.jpg)
![Protein QC systems. The chaperone, ubiquitin-proteasome, and autophagy | Download](https://1mg.info/0/u/a/1523.jpg)
![Chaperone-mediated autophagy. The KFERQ sequence of the substrate | Download](https://1mg.info/0/u/a/1524.jpg)
![シャペロン介在性オートファジー(CMA)と神経変性疾患](https://1mg.info/0/u/a/1525.jpg)
![Proteins are recognized for CMA by a CMA-targeting motif (i) The CMA | Download](https://1mg.info/0/u/a/1526.jpg)
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- 英
- KFERQ protein
- 関
- KFERQ様モチーフ、KFERQ配列