English Journal

Environmental estrogens in a drinking water reservoir area in Shanghai: Occurrence, colloidal contribution and risk assessment.

Nie M1, Yang Y2, Liu M3, Yan C4, Shi H3, Dong W5, Zhou JL4.Author information 1Key Laboratory of Geographic Information Science of the Ministry of Education, School of Resource and Environmental Sciences, East China Normal University, 3663 Zhongshan North Road, Shanghai 200062, China; Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention, Department of Environmental Science and Engineering, Fudan University, 220 Handan Road, Shanghai 200433, China.2Key Laboratory of Geographic Information Science of the Ministry of Education, School of Resource and Environmental Sciences, East China Normal University, 3663 Zhongshan North Road, Shanghai 200062, China; State Key Laboratory of Estuarine and Coastal Research, East China Normal University, 3663 Zhongshan North Road, Shanghai 200062, China. Electronic address: yyang@geo.ecnu.edu.cn.3Key Laboratory of Geographic Information Science of the Ministry of Education, School of Resource and Environmental Sciences, East China Normal University, 3663 Zhongshan North Road, Shanghai 200062, China.4State Key Laboratory of Estuarine and Coastal Research, East China Normal University, 3663 Zhongshan North Road, Shanghai 200062, China.5Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention, Department of Environmental Science and Engineering, Fudan University, 220 Handan Road, Shanghai 200433, China.AbstractThe occurrence and multi-phase distribution of six environmental estrogen compounds were investigated in a drinking water reservoir area by analyzing estrogens in suspended particulate matter (SPM), filtrate (conventional dissolved phase, <1μm), permeate (truly soluble phase, <1kDa) and retentate (colloidal phase, 1kDa to 1μm). The estrogen concentrations at different sites occurred in the following order: animal feed operation (AFO) wastewater-affected streams>tributaries>main stream channel. Correlation analysis showed that organic carbon (OC) contents had significantly positive correlations with environmental estrogens in filtrate, SPM and colloidal phases, respectively, indicating the important role played by OC. Aquatic colloids, often neglected, showed a much higher sorption capability of environmental estrogens compared to SPM. Similar Kcoc values in three types of sampling sites showed that colloids could be transported from AFO wastewater to tributaries and further into the main river channel. Mass balance calculations showed that 14.5-68.4% of OP, 4.5-32.1% of BPA, 2.0-58.4% of E1, 8.36-72.0% of E2, 0-20.6% of EE2, 3.4-62.7% of E3 and 8.3-36.1% of total estrogens were associated with colloidal fractions, suggesting that the colloids could act as a significant sink for environmental estrogens. Risk assessment demonstrated that the occurrence of environmental estrogens might pose a risk to aquatic organisms in the study area.
The Science of the total environment.Sci Total Environ.2013 Dec 20. pii: S0048-9697(13)01464-2. doi: 10.1016/j.scitotenv.2013.12.010. [Epub ahead of print]
The occurrence and multi-phase distribution of six environmental estrogen compounds were investigated in a drinking water reservoir area by analyzing estrogens in suspended particulate matter (SPM), filtrate (conventional dissolved phase, <1μm), permeate (truly soluble phase, <1kDa) and reten
PMID 24364991

An improved model for predicting radiation pneumonitis incorporating clinical and dosimetric variables.

Jenkins P1, Watts J.Author information 1Gloucestershire Oncology Centre, Cheltenham General Hospital, Cheltenham, UK. peter.jenkins@glos.nhs.ukAbstractPURPOSE: Single dose-volume metrics are of limited value for the prediction of radiation pneumonitis (RP) in day-to-day clinical practice. We investigated whether multiparametric models that incorporate clinical and physiologic factors might have improved accuracy.
International journal of radiation oncology, biology, physics.Int J Radiat Oncol Biol Phys.2011 Jul 15;80(4):1023-9. doi: 10.1016/j.ijrobp.2010.03.058. Epub 2011 May 3.
PURPOSE: Single dose-volume metrics are of limited value for the prediction of radiation pneumonitis (RP) in day-to-day clinical practice. We investigated whether multiparametric models that incorporate clinical and physiologic factors might have improved accuracy.METHODS AND MATERIALS: The records
PMID 21543165

Colloids as a sink for certain pharmaceuticals in the aquatic environment.

Maskaoui K1, Zhou JL.Author information 1School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QG, UK.AbstractBACKGROUND, AIM, AND SCOPE: The occurrence and fate of pharmaceuticals in the aquatic environment is recognized as one of the emerging issues in environmental chemistry and as a matter of public concern. Existing data tend to focus on the concentrations of pharmaceuticals in the aqueous phase, with limited studies on their concentrations in particulate phase such as sediments. Furthermore, current water quality monitoring does not differentiate between soluble and colloidal phases in water samples, hindering our understanding of the bioavailability and bioaccumulation of pharmaceuticals in aquatic organisms. In this study, an investigation was conducted into the concentrations and phase association (soluble, colloidal, suspended particulate matter or SPM) of selected pharmaceuticals (propranolol, sulfamethoxazole, meberverine, thioridazine, carbamazepine, tamoxifen, indomethacine, diclofenac, and meclofenamic acid) in river water, effluents from sewage treatment works (STW), and groundwater in the UK.
Environmental science and pollution research international.Environ Sci Pollut Res Int.2010 May;17(4):898-907. doi: 10.1007/s11356-009-0279-1. Epub 2009 Dec 19.
BACKGROUND, AIM, AND SCOPE: The occurrence and fate of pharmaceuticals in the aquatic environment is recognized as one of the emerging issues in environmental chemistry and as a matter of public concern. Existing data tend to focus on the concentrations of pharmaceuticals in the aqueous phase, with
PMID 20024675

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