KCNQ2カリウムチャネル
WordNet
- direct the flow of; "channel information towards a broad audience" (同)canalize, canalise
- a television station and its programs; "a satellite TV channel"; "surfing through the channels"; "they offer more than one hundred channels" (同)television channel, TV channel
- a passage for water (or other fluids) to flow through; "the fields were crossed with irrigation channels"; "gutters carried off the rainwater into a series of channels under the street"
- (often plural) a means of communication or access; "it must go through official channels"; "lines of communication were set up between the two firms" (同)communication channel, line
- a path over which electrical signals can pass; "a channel is typically what you rent from a telephone company" (同)transmission channel
- a deep and relatively narrow body of water (as in a river or a harbor or a strait linking two larger bodies) that allows the best passage for vessels; "the ship went aground in the channel"
- a light soft silver-white metallic element of the alkali metal group; oxidizes rapidly in air and reacts violently with water; is abundant in nature in combined forms occurring in sea water and in carnallite and kainite and sylvite (同)K, atomic number 19
- official routes of communication; "you have to go through channels"
PrepTutorEJDIC
- 〈C〉『水路』(川・湾・運河の船の通行ができる深い部分) / 〈U〉河床・川底 / 〈C〉『海峡』 / 〈C〉みぞ(groove),(道路の)水渠(すいきょ) / 《複数形で》(運搬・伝達の)正式の経路(手続き);(一般に)経路 / 〈C〉(テレビ・ラジオの)チャンネル / …‘に'水路を開く / …‘に'みぞを堀る / …'を'伝える,流す
- ポタシウム,カリウム(金属元素;化学記号はK)
UpToDate Contents
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English Journal
- Synthesis and Evaluation of Potent KCNQ2/3-Specific Channel Activators.
- Kumar M1, Reed N1, Liu R1, Aizenman E1, Wipf P2, Tzounopoulos T2.
- Molecular pharmacology.Mol Pharmacol.2016 Jun;89(6):667-77. doi: 10.1124/mol.115.103200. Epub 2016 Mar 22.
- KQT-like subfamily (KCNQ) channels are voltage-gated, noninactivating potassium ion channels, and their down-regulation has been implicated in several hyperexcitability-related disorders, including epilepsy, neuropathic pain, and tinnitus. Activators of these channels reduce the excitability of cent
- PMID 27005699
- A Kv7.2 mutation associated with early onset epileptic encephalopathy with suppression-burst enhances Kv7/M channel activity.
- Devaux J1, Abidi A2,3, Roubertie A4,5, Molinari F6,7, Becq H6,7, Lacoste C2,3,8, Villard L2,3, Milh M2,3,8, Aniksztejn L6,7.
- Epilepsia.Epilepsia.2016 May;57(5):e87-93. doi: 10.1111/epi.13366. Epub 2016 Mar 31.
- Mutations in the KCNQ2 gene encoding the voltage-gated potassium channel subunit Kv7.2 cause early onset epileptic encephalopathy (EOEE). Most mutations have been shown to induce a loss of function or to affect the subcellular distribution of Kv7 channels in neurons. Herein, we investigated function
- PMID 27030113
- KCNQ Potassium Channels Modulate Sensitivity of Skin Down-hair (D-hair) Mechanoreceptors.
- Schütze S1, Orozco IJ1, Jentsch TJ2.
- The Journal of biological chemistry.J Biol Chem.2016 Mar 11;291(11):5566-75. doi: 10.1074/jbc.M115.681098. Epub 2016 Jan 5.
- M-current-mediating KCNQ (Kv7) channels play an important role in regulating the excitability of neuronal cells, as highlighted by mutations in Kcnq2 and Kcnq3 that underlie certain forms of epilepsy. In addition to their expression in brain, KCNQ2 and -3 are also found in the somatosensory system.
- PMID 26733196
Japanese Journal
- Sodium and potassium channel dysfunctions in rare and common idiopathic epilepsy syndromes
- A de novo KCNQ2 mutation detected in non-familial benign neonatal convulsions
- Does metabolism of (S)-N-〔1-(3-morpholin-4-ylphenyl)ethyl〕-3-phenylacrylamide occur at the morpholine ring? Quantum mechanical and molecular dynamics studies (Special issue on ACCMS working group meeting on clusters and nanomaterials)
★リンクテーブル★
[★]
- 英
- KCNQ2 potassium channel
[★]
- 川床、川底。水路、河道
- 海峡
- 水管、導管
- 溝
- 経路、ルート。道筋、方向
- 関
- ion channel、ionic channel
[★]
シアン化カリウム
- 関
- potassium cyanide