Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/09/05 23:06:40」(JST)

English Journal

Far upstream element binding protein 1 activates translation of p27(Kip1) mRNA through its internal ribosomal entry site.

Zheng Y, Miskimins WK.SourceCancer Biology Research Center, Sanford Research/USD, Sioux Falls, SD 57001, USA; Division of Basic Biomedical Sciences, Sanford School of Medicine of the University of South Dakota, Vermillion, SD 57069, USA; Department of Lymphoma and Myeloma, University of Texas, MD Anderson Cancer Center, Houston, TX 77054, USA.
The international journal of biochemistry & cell biology.Int J Biochem Cell Biol.2011 Nov;43(11):1641-8. Epub 2011 Aug 9.
The cyclin dependent kinase inhibitor p27 plays an important role in controlling the eukaryotic cell cycle by regulating progression through G1 and entry into S phase. It is often elevated during differentiation and under conditions of cellular stress. In contrast, it is commonly downregulated in ca
PMID 21855647

In silico analysis of IRES RNAs of foot-and-mouth disease virus and related picornaviruses.

Burks JM, Zwieb C, Muller F, Wower IK, Wower J.SourceDepartment of Animal Sciences, Auburn University, 210 Upchurch Hall, Auburn, AL, 36849-5415, USA.
Archives of virology.Arch Virol.2011 Oct;156(10):1737-47. Epub 2011 Jun 17.
Foot-and-mouth disease virus (FMDV) uses an internal ribosome entry site (IRES), a highly structured segment of its genomic RNA, to hijack the translational apparatus of an infected host. Computational analysis of 162 type II picornavirus IRES RNA sequences yielded secondary structures that included
PMID 21681504

Expression of Recombinant Human Interferon-γ with Antiviral Activity in the Bi-Cistronic Baculovirus-Insect/Larval System

CHEN Wen-Shuo,VILLAFLORES Oliver B.,JINN Tzyy-Rong,CHAN Ming-Tsair,CHANG Yen-Chung,WU Tzong-Yuan
Bioscience, Biotechnology, and Biochemistry 75(7), 1342-1348, 2011
… A bi-cistronic baculovirus-insect/larval system containing a polyhedron promoter, an internal ribosome entry site (IRES), and an egfp gene was developed as a cost-effective platform for the production of recombinant human interferon gamma (rhIFN-γ). … These findings suggest that this IRES-based expression system is a simple and inexpensive alternative for large-scale protein production in anti-viral research. …
NAID 130000940521

Generation of Adeno-Associated Virus Vector Enabling Functional Expression of Oxytocin Receptor and Fluorescence Marker Genes Using the Human eIF4G Internal Ribosome Entry Site Element

SATO Keisuke,DATE Shiori,AOYAGI Yumi,KASAHARA Yoshiyuki,NAWA Akihiko,MIZUKAMI Hiroaki,HIDEMA Shizu,OZAWA Keiya,NISHIMORI Katsuhiko
Bioscience, biotechnology, and biochemistry 73(9), 2145-2148, 2009-09-23
… We developed the AAV-Oxtr-IRES-Venus vector to rescue the oxytocin receptor (Oxtr) gene functionally at restricted regions in the brains of Oxtr knockout mice. … First we chose human eIF4G gene-derived IRES to co-express Venus, a fluorescent marker gene, with Oxtr. …
NAID 10027546295

リンク元	「配列内リボソーム進入部位」「internal ribosomal entry site」
拡張検索	「IRES依存的翻訳」
関連記事	「IR」

配列内リボソーム進入部位 : 40 件
内部リボソーム進入シグナル : 5 件