関: Inhibitory postsynaptic currents

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1. 幹細胞の概要 overview of stem cells
2. Genetics: glossary of terms
3. 造血および幹細胞の機能の概要 overview of hematopoiesis and stem cell function
4. 肝細胞移植 hepatocyte transplantation
5. 小児における赤血球産生低下による貧血 anemia in children due to decreased red blood cell production

English Journal

Gene Expression Studies on Human Trisomy 21 iPSCs and Neurons: Towards Mechanisms Underlying Down's Syndrome and Early Alzheimer's Disease-Like Pathologies.

Weick JP1, Kang H, Bonadurer GF 3rd, Bhattacharyya A.
Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2016;1303:247-65. doi: 10.1007/978-1-4939-2627-5_15.
The cause of Alzheimer disease (AD) is not well understood and there is no cure. Our ability to understand the early events in the course of AD is severely limited by the difficulty of identifying individuals who are in the early, preclinical stage of this disease. Most individuals with Down's syndr
PMID 26235072

Generating induced pluripotent stem cell derived endothelial cells and induced endothelial cells for cardiovascular disease modelling and therapeutic angiogenesis.

Clayton ZE1, Sadeghipour S2, Patel S3.
International journal of cardiology.Int J Cardiol.2015 Oct 15;197:116-22. doi: 10.1016/j.ijcard.2015.06.038. Epub 2015 Jun 18.
Standard therapy for atherosclerotic coronary and peripheral arterial disease is insufficient in a significant number of patients because extensive disease often precludes effective revascularization. Stem cell therapy holds promise as a supplementary treatment for these patients, as pre-clinical an
PMID 26123569

A novel human model of the neurodegenerative disease GM1 gangliosidosis using induced pluripotent stem cells demonstrates inflammasome activation.

Son MY1,2, Kwak JE1, Seol B1, Lee da Y1, Jeon H1, Cho YS1,2.
The Journal of pathology.J Pathol.2015 Sep;237(1):98-110. doi: 10.1002/path.4551. Epub 2015 May 26.
GM1 gangliosidosis (GM1) is an inherited neurodegenerative disorder caused by mutations in the lysosomal β-galactosidase (β-gal) gene. Insufficient β-gal activity leads to abnormal accumulation of GM1 gangliosides in tissues, particularly in the central nervous system, resulting in progressive ne
PMID 25925601

Japanese Journal

Early pathogenesis of Duchenne muscular dystrophy modelled in patient-derived human induced pluripotent stem cells.

Shoji Emi,Sakurai Hidetoshi,Nishino Tokiko,Nakahata Tatsutoshi,Heike Toshio,Awaya Tomonari,Fujii Nobuharu,Manabe Yasuko,Matsuo Masafumi,Sehara-Fujisawa Atsuko
Scientific reports 5, 2015-08-20
… These results suggest that the early pathogenesis of DMD can be effectively modelled in skeletal myotubes induced from patient-derived iPSCs, thereby enabling the development and evaluation of novel drugs. …
NAID 120005649326

iPS細胞研究最前線 : 疾患モデルから臓器再生まで(Vol.14)患者由来iPS細胞を用いた神経疾患研究

津下到,鈴木茂彦,内藤素子 [他]
医学のあゆみ 252(7), 824-828, 2015-02-14
NAID 40020358078

iPS細胞研究最前線 : 疾患モデルから臓器再生まで(Vol.13)iPS細胞を用いた三次元臓器の作製

宮本竜之,中内啓光
医学のあゆみ 252(4), 315-320, 2015-01-24
NAID 40020333027

Related Pictures

Figure 1: Generating iPSCs. Gene delivery To create iPSCs, scientist expose normal (iPSCs).Del artículo Wu&Hochedlinger iPSCs can then be differentiated via Revolutionary Human Stem Cell Trial for generating, analyzing and using iPSCs Eat Drink Live Science: Disease in a plate ipscs can be used for disease modeling and