- 関
- isosorbide-5-mononitrate
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English Journal
- Organic Nitrate Therapy, Nitrate Tolerance, and Nitrate-Induced Endothelial Dysfunction: Emphasis on Redox Biology and Oxidative Stress.
- Daiber A1, Münzel T1.
- Antioxidants & redox signaling.Antioxid Redox Signal.2015 Oct 10;23(11):899-942. doi: 10.1089/ars.2015.6376. Epub 2015 Sep 24.
- Organic nitrates, such as nitroglycerin (GTN), isosorbide-5-mononitrate and isosorbide dinitrate, and pentaerithrityl tetranitrate (PETN), when given acutely, have potent vasodilator effects improving symptoms in patients with acute and chronic congestive heart failure, stable coronary artery diseas
- PMID 26261901
- Synthesis of 2-[(18) F]Fluoro-2-deoxyisosorbide 5-mononitrate and Assessment of Its in vivo Biodistribution as Determined by Dynamic Positron Emission Tomography (PET).
- Santschi N1,2, Wagner S3, Daniliuc C1, Hermann S2,4, Schäfers M5,6,7, Gilmour R8,9.
- ChemMedChem.ChemMedChem.2015 Oct;10(10):1724-32. doi: 10.1002/cmdc.201500275. Epub 2015 Aug 12.
- Herein we disclose the synthesis of 2-fluoro-2-deoxyisosorbide 5-mononitrate (2F-IS-5MN), a fluorinated analogue of the commonly prescribed vasodilator isosorbide 5-mononitrate (IS-5MN). X-ray structural data for IS-5MN and its C2-epimeric congener IM-5MN are presented together with structural data
- PMID 26267858
- Prevention of Rebleeding From Esophageal Varices in Patients With Cirrhosis Receiving Small-Diameter Stents Versus Hemodynamically Controlled Medical Therapy.
- Sauerbruch T1, Mengel M2, Dollinger M3, Zipprich A4, Rössle M5, Panther E5, Wiest R6, Caca K7, Hoffmeister A8, Lutz H9, Schoo R10, Lorenzen H11, Trebicka J12, Appenrodt B13, Schepke M14, Fimmers R11; German Study Group for Prophylaxis of Variceal Rebleeding.
- Gastroenterology.Gastroenterology.2015 Sep;149(3):660-8.e1. doi: 10.1053/j.gastro.2015.05.011. Epub 2015 May 16.
- BACKGROUND & AIMS: Patients with cirrhosis and variceal hemorrhage have a high risk of rebleeding. We performed a prospective randomized trial to compare the prevention of rebleeding in patients given a small-diameter covered stent vs those given hepatic venous pressure gradient (HVPG)-based med
- PMID 25989386
Japanese Journal
- Sustained reduction of exercise perfusion defect extent and severity with isosorbide mononitrate (Imdur) as demonstrated by means of technetium 99m sestamibi
Related Links
- Imdur (isosorbide mononitrate) is a nitrate used to prevent angina attacks. Includes Imdur side effects, interactions and indications.
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