English Journal

Dextrans produced by lactic acid bacteria exhibit antiviral and immunomodulatory activity against salmonid viruses.

Nácher-Vázquez M1, Ballesteros N1, Canales Á1, Rodríguez Saint-Jean S1, Pérez-Prieto SI1, Prieto A1, Aznar R2, López P3.
Carbohydrate polymers.Carbohydr Polym.2015 Jun 25;124:292-301. doi: 10.1016/j.carbpol.2015.02.020. Epub 2015 Feb 21.
Viral infections in the aquaculture of salmonids can lead to high mortality and substantial economic losses. Thus, there is industrial interest in new molecules active against these viruses. Here we describe the production, purification, and the physicochemical and structural characterization of hig
PMID 25839823

An oral DNA vaccine against infectious haematopoietic necrosis virus (IHNV) encapsulated in alginate microspheres induces dose-dependent immune responses and significant protection in rainbow trout (Oncorrhynchus mykiss).

Ballesteros NA1, Alonso M2, Saint-Jean SR1, Perez-Prieto SI3.
Fish & shellfish immunology.Fish Shellfish Immunol.2015 Jun 5. pii: S1050-4648(15)30028-0. doi: 10.1016/j.fsi.2015.05.045. [Epub ahead of print]
Administered by intramuscular injection, a DNA vaccine (pIRF1A-G) containing the promoter regions upstream of the rainbow trout interferon regulatory factor 1A gene (IRF1A) driven the expression of the infectious hematopoietic necrosis virus (IHNV) glycoprotein (G) elicited protective immune respons
PMID 26054788

Masson L1, Passmore JA2, Liebenberg LJ3, Werner L3, Baxter C3, Arnold KB4, Williamson C1, Little F5, Mansoor LE3, Naranbhai V3, Lauffenburger DA4, Ronacher K6, Walzl G6, Garrett NJ3, Williams BL7, Couto-Rodriguez M7, Hornig M7, Lipkin WI7, Grobler A3, Abdool Karim Q8, Abdool Karim SS8.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.Clin Infect Dis.2015 Apr 21. pii: civ298. [Epub ahead of print]
BACKGROUND: Women in Africa, especially young women, have very high human immunodeficiency virus (HIV) incidence rates that cannot be fully explained by behavioral risks. We investigated whether genital inflammation influenced HIV acquisition in this group.METHODS: Twelve selected cytokines, i
PMID 25900168

Japanese Journal

吉水守,笠井久会,渡邉研一
腸内細菌学雑誌 28(1), 7-14, 2014
… し，ペレットに10％の割合で菌体培養液を混ぜ経口投与すると，腸内容物も強い抗IHNV活性を示した．分離菌添加ペレットを3週間ニジマスおよびサクラマスに投与後，100TCID50/mlのIHNVで浸漬攻撃を行ったところ有意な差が認められた．マツカワやヒラメの腸内細菌であるVibrio属細菌を対象に，抗IHNV，サケ科魚ヘルペスウイルス（OMV）およびウイルス性神経壊死症（VNN）原因ノダウ …
NAID 130003392112

小原昌和,小川滋,笠井久会,吉水守
水産増殖 58(1), 37-43, 2010-03-20
… 冷水病菌，せっそう病菌，IHNVおよびOMVで汚染したニジマス卵を供試して，等調液洗卵の除菌効果を定量的に明らかにするとともに，ニジマス卵を使用した感染試験を行い，卵内感染の防止効果について検証した。 …
NAID 120005317007

小原昌和,小川滋,笠井久会 [他],吉水守
水産増殖 = The aquiculture 58(1), 37-43, 2010-03-20
… 冷水病菌、せっそう病菌、IHNVおよびOMVで汚染したニジマス卵を供試して、等調液洗卵の除菌効果を定量的に明らかにするとともに、ニジマス卵を使用した感染試験を行い、卵内感染の防止効果について検証した。 …
NAID 10029845708