- リグモソモイデス上科
English Journal
- Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis.
- Wu D, Molofsky AB, Liang HE, Ricardo-Gonzalez RR, Jouihan HA, Bando JK, Chawla A, Locksley RM.SourceHoward Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94143-0795, USA.
- Science (New York, N.Y.).Science.2011 Apr 8;332(6026):243-7. Epub 2011 Mar 24.
- Eosinophils are associated with helminth immunity and allergy, often in conjunction with alternatively activated macrophages (AAMs). Adipose tissue AAMs are necessary to maintain glucose homeostasis and are induced by the cytokine interleukin-4 (IL-4). Here, we show that eosinophils are the major IL
- PMID 21436399
- Basophils are the major producers of IL-4 during primary helminth infection.
- van Panhuys N, Prout M, Forbes E, Min B, Paul WE, Le Gros G.SourceMalaghan Institute of Medical Research, Wellington 6012, New Zealand. vanpanhuysn@niaid.nih.gov
- Journal of immunology (Baltimore, Md. : 1950).J Immunol.2011 Mar 1;186(5):2719-28. Epub 2011 Jan 26.
- IL-4 production by leukocytes is a key regulatory event that occurs early in the type 2 immune response, which induces allergic reactions and mediates expulsion of parasites. CD4(+) T cells and basophils are thought to be the key cell types that produce IL-4 during a type 2 response. In this study,
- PMID 21270410
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