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English Journal

Time course Haemophilus parasuis infection reveals pathological differences between virulent and non-virulent strains in the respiratory tract.

Bello-Orti B1, Costa-Hurtado M1, Martinez-Moliner V1, Segalés J2, Aragon V3.
Veterinary microbiology.Vet Microbiol.2014 Jun 4;170(3-4):430-7. doi: 10.1016/j.vetmic.2014.01.011. Epub 2014 Feb 3.
Haemophilus parasuis is a common inhabitant of the upper respiratory tract of pigs and the etiological agent of Glässer's disease. However, the host-pathogen interaction remains to be well understood. In this work, 33 colostrum-deprived pigs were divided in 4 groups and each group was inoculated in
PMID 24613292

Wang C1, Chen F, Hu H, Li W, Wang Y, Chen P, Liu Y, Ku X, He Q, Chen H, Xue F.
Journal of molecular microbiology and biotechnology.J Mol Microbiol Biotechnol.2014 May 22;24(2):120-129. [Epub ahead of print]
Synthetically designed antimicrobial peptides (AMPs) present the potential of replacing antibiotics in the treatment of bacterial infections. However, microbial resistance to AMPs has been reported and little is known regarding the underlying mechanism of such resistance. The naturally occurring AMP
PMID 24862339

Development of a neutralizing mouse-pig chimeric antibody with therapeutic potential against Haemophilus parasuis in Pichia pastoris.

Chai Z1, Fu F, Jiang F, Tian H, Wang Z, Zheng N, Zhang X, Wang X, Li X.
FEMS microbiology letters.FEMS Microbiol Lett.2014 May;354(2):85-91. doi: 10.1111/1574-6968.12437. Epub 2014 Apr 16.
Haemophilus parasuis is one of the most important bacterial diseases of pigs worldwide. The lack of a vaccine against a broad spectrum of strains and the limitation of antimicrobial susceptibility hamper the control of disease. In this study, we cloned the constant regions of gamma heavy chains and
PMID 24698098

Immunological Identification and Characterization of Extracellular Serine Protease-Like Protein Encoded in a Putative espP2 Gene of Haemophilus parasuis

ZHANG Nian-Zhang,CHU Yue-Feng,GAO Peng-Cheng,ZHAO Ping,HE Ying,LU Zhong-Xin
Journal of Veterinary Medical Science 74(8), 983-987, 2012
… Haemophilus parasuis is known to produce a group of virulence-associated autotransporter (AT) proteins, VtaAs; … parasuis, this putative AT gene was successfully amplified from H. … parasuis serotype 5 field strain HPS0819, cloned and sequenced. … parasuis by using antiserum to the purified ESP-like protein, and antibodies against the recombinant ESP-like protein were detected in a selected serum from pigs with experimental H. …
NAID 130001879789