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any living or extinct member of the family Hominidae characterized by superior intelligence, articulate speech, and erect carriage (同)man, human_being, human

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/09/27 12:12:03」(JST)

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1. 悪性高熱症の易罹患性 susceptibility to malignant hyperthermia
2. 乳癌におけるホルモン受容体：臨床的有用性および検査精度向上のためのガイドラインの
推奨 hormone receptors in breast cancer clinical utility and guideline recommendations to improve test accuracy
3. 小児および思春期における性の分化および性同一性障害の臨床症状の概要 overview of gender development and clinical presentation of gender nonconformity in children and adolescents
4. トラスツズマブおよびその他の抗HER2薬の心毒性 cardiotoxicity of trastuzumab and other her2 targeted agents
5. ALA脱水酵素欠損性ポルフィリン症 ala dehydratase porphyria

English Journal

Tailoring and histochemical application of fluorescent homo-dimeric styryl dyes using frozen sections: From peroxidase substrates to new cytochemical probes for mast cells, keratin, cartilage and nucleic acids.

Krieg R, Eitner A, Halbhuber KJ.SourceInstitute of Anatomy/Anatomy II, Friedrich-Schiller-University Jena, Teichgraben 7, D-07743 Jena, Germany.
Acta histochemica.Acta Histochem.2011 Nov;113(7):682-702. Epub 2011 Apr 8.
Homo-dimers of styryl dyes were chemically tailored in order to become specific cytochemical probes for use in the life sciences. Histochemical applications using fixed cryotome sections are discussed. It is concluded, that homo-dimerization of specific styryl substrates of peroxidase (PO) by way of
PMID 21477847

Dependence on different Rab GTPases for the trafficking of CXCR4 and CCR5 homo or heterodimers between the endoplasmic reticulum and plasma membrane in Jurkat cells.

Charette N, Holland P, Frazer J, Allen H, Dupre DJ.AbstractMuch is known about G protein coupled receptor trafficking and internalization following agonist stimulation. However, much less is known about outward trafficking of receptors from synthesis in the endoplasmic reticulum to the plasma membrane, or the role that trafficking might play in the assembly of receptor signaling complexes, important for targeting, specificity, and rapidity of subsequent signaling events. Up to now, very little is understood about receptor hetero-oligomers other than the fact that their assembly is done rapidly after biosynthesis. In our study we use bimolecular fluorescence complementation to selectively follow receptor dimers when expressed in Jurkat cells in order to clarify the trafficking itinerary those receptors follow to reach the plasma membrane and the resulting effect on signal transduction. CXCR4 and CCR5, previously shown to form both homo and hetero-oligomers, were used as our model to understand the specificities of trafficking along the anterograde pathway. The CXCR4 homodimer relies on Rabs2, 6 and 8 for anterograde transport regardless of the presence of endogenous CD4. The CCR5 homodimer relies on Rabs1 and 11 when CD4 is absent, but Rabs1 and 8 when CD4 was present. Interestingly, similar to the CCR5 homodimer, the CXCR4-CCR5 heterodimer relied on Rabs1 and 11 but also required Rab2 when CD4 was absent, and only Rab 1 when CD4 was present. Our results demonstrate that, although the receptors composing the heterodimeric complex are the same as in the homodimeric ones, the heterodimer traffics and signals differently than each homodimer. Our study demonstrates the importance of considering the receptor heterodimers as distinct signaling entities that should be carefully and individually characterized.
Cellular signalling.Cell Signal.2011 Nov;23(11):1738-49. Epub 2011 Jun 24.
Much is known about G protein coupled receptor trafficking and internalization following agonist stimulation. However, much less is known about outward trafficking of receptors from synthesis in the endoplasmic reticulum to the plasma membrane, or the role that trafficking might play in the assembly
PMID 21723943

Japanese Journal

Power Efficiency Improvement of White Phosphorescent Organic Light-Emitting Diode with Thin Double-Emitting Layers and Hole-Trapping Mechanism

Juang Fuh-Shyang,Hong Lin-Ann,Wang Shun-Hsi [他],Tsai Yu-Sheng,Gao Ming-Hong,Chi Yun,Shieh Han-Ping,Hsu Jen-Sung
Jpn J Appl Phys 50(4), 04DK04-04DK04-4, 2011-04-25
… An Os complex with a high-lying highest occupied molecular orbital (HOMO) energy level (trapping holes) is codoped at the interface between emitting layers and an exciton-formation zone is expanded to obtain a white PHOLED with high efficiency. …
NAID 150000055637

Flexible Command : A Solution to the Symmetry Problem of Adjunction, Scrambling, and Dislocation

Arikawa Koji
桃山学院大学人間科学 (40), 65-200, 2011-03-30
… Human language (CHL) has evolved from the mutated brain of Homo Habilis about two million years ago, and what the system does is aimlessly multiply a binary-branching structure (two-membered-set building). … Human language has not evolved for the purpose of communication as demonstrated by the fact that Homo Sapiens (us) as a species have disclosed the worst quality of communicative competence: the key words for understanding our species are lie (fraud) and war (murder). …
NAID 110008425529